Matt Hall
@cispt2.bsky.social
🇦🇺 SD at NCATS, all about treatments for rare diseases, drug discovery and technologies. Views my own. Etc.
As a little boy, my grandparents gave me this book. This story of Pasteur is the one that made me want to be a scientist. And it doesn’t even mention optical activity!!
October 2, 2025 at 1:50 PM
As a little boy, my grandparents gave me this book. This story of Pasteur is the one that made me want to be a scientist. And it doesn’t even mention optical activity!!
It reminds me of this banger:
"Revised Estimates for the Number of Human and Bacteria Cells in the Body"
- We estimate the total # of bacteria in the 70 kg "reference man" to be 3.8X10^13.
- # of bacteria in the body is actually of the same order as the # of human cells, & total mass is ~0.2 kg.
"Revised Estimates for the Number of Human and Bacteria Cells in the Body"
- We estimate the total # of bacteria in the 70 kg "reference man" to be 3.8X10^13.
- # of bacteria in the body is actually of the same order as the # of human cells, & total mass is ~0.2 kg.
September 22, 2025 at 4:54 PM
It reminds me of this banger:
"Revised Estimates for the Number of Human and Bacteria Cells in the Body"
- We estimate the total # of bacteria in the 70 kg "reference man" to be 3.8X10^13.
- # of bacteria in the body is actually of the same order as the # of human cells, & total mass is ~0.2 kg.
"Revised Estimates for the Number of Human and Bacteria Cells in the Body"
- We estimate the total # of bacteria in the 70 kg "reference man" to be 3.8X10^13.
- # of bacteria in the body is actually of the same order as the # of human cells, & total mass is ~0.2 kg.
I missed this paper at the time but love this kind of study:
"The total mass, number, and distribution of immune cells in the human body"
"an average individual’s immune system consists of approximately 1.8 trillion cells, weighing around 1.2 kg"
www.pnas.org/doi/10.1073/...
"The total mass, number, and distribution of immune cells in the human body"
"an average individual’s immune system consists of approximately 1.8 trillion cells, weighing around 1.2 kg"
www.pnas.org/doi/10.1073/...
September 22, 2025 at 4:51 PM
I missed this paper at the time but love this kind of study:
"The total mass, number, and distribution of immune cells in the human body"
"an average individual’s immune system consists of approximately 1.8 trillion cells, weighing around 1.2 kg"
www.pnas.org/doi/10.1073/...
"The total mass, number, and distribution of immune cells in the human body"
"an average individual’s immune system consists of approximately 1.8 trillion cells, weighing around 1.2 kg"
www.pnas.org/doi/10.1073/...
I rarely post about work, but in writing this email today asking how to be reimbursed for the cost of hosting a scientific visitor I wrote this explainer. This is not a complaint - but shows how we have to use our own salaries to enrich our environment and the commitment that takes
September 17, 2025 at 2:04 PM
I rarely post about work, but in writing this email today asking how to be reimbursed for the cost of hosting a scientific visitor I wrote this explainer. This is not a complaint - but shows how we have to use our own salaries to enrich our environment and the commitment that takes
When the day is done
September 10, 2025 at 1:20 AM
When the day is done
One of the posters from my group was on a drug discovery strategy for inhibitors of biliverdin reductase - a target relevant for several rare diseases. Our postbac Christa did an amazing job presenting her work - it’s a collab with scientists at Einstein.
September 9, 2025 at 8:51 PM
One of the posters from my group was on a drug discovery strategy for inhibitors of biliverdin reductase - a target relevant for several rare diseases. Our postbac Christa did an amazing job presenting her work - it’s a collab with scientists at Einstein.
Meeting my trainee for coffee and project strategizing in the amazing NIH Clinical Center. Inspiring.
September 9, 2025 at 7:34 PM
Meeting my trainee for coffee and project strategizing in the amazing NIH Clinical Center. Inspiring.
But the poster sessions are buzzing - so much amazing NIH science on show! I got in trouble for standing on a ledge to take this photo….. you’re welcome
September 9, 2025 at 3:09 PM
But the poster sessions are buzzing - so much amazing NIH science on show! I got in trouble for standing on a ledge to take this photo….. you’re welcome
Sometimes you make a poster, then realize the world isn’t ready
September 9, 2025 at 3:05 PM
Sometimes you make a poster, then realize the world isn’t ready
It’s that time of year again - NIH Research Festival !
September 9, 2025 at 2:10 PM
It’s that time of year again - NIH Research Festival !
I must be doing something right - daughter raided my vinyl.
September 3, 2025 at 12:44 AM
I must be doing something right - daughter raided my vinyl.
I show this dedication in Volume 1 to 'Inorganic Syntheses' to the organic chemists whenever I can. Solid.
July 31, 2025 at 1:26 AM
I show this dedication in Volume 1 to 'Inorganic Syntheses' to the organic chemists whenever I can. Solid.
And @snailmail.bsky.social have another fan
July 21, 2025 at 4:28 PM
And @snailmail.bsky.social have another fan
They were - as always - phenomenal
July 21, 2025 at 4:27 PM
They were - as always - phenomenal
Am I the only scientist who likes to cool off in the coldroom on a hot day?
June 26, 2025 at 6:25 PM
Am I the only scientist who likes to cool off in the coldroom on a hot day?
The new NIH Director presents at his first Town Hall - and it’s a FULL HOUSE in the Clinical Center
May 19, 2025 at 5:42 PM
The new NIH Director presents at his first Town Hall - and it’s a FULL HOUSE in the Clinical Center
Farewell to Nate Hoxie, who leaves our group after an amazing period of time developing mass spec approaches for drug discovery and assay development. As is tradition for our group, Nate receives the complete Sherlock Holmes canon. Full of life lessons.
April 14, 2025 at 5:25 PM
Farewell to Nate Hoxie, who leaves our group after an amazing period of time developing mass spec approaches for drug discovery and assay development. As is tradition for our group, Nate receives the complete Sherlock Holmes canon. Full of life lessons.
We've added another success - NUMBER 60 !!! - to our intramural list of FDA drug approvals and clinical trial clearances here at NCATS.
Latest is cross-NIH partnership w/ Amy Newman at NIINDS with IND approved for VK4-116 for opioid use disorder.
See all our success: ncats.nih.gov/research/our...
Latest is cross-NIH partnership w/ Amy Newman at NIINDS with IND approved for VK4-116 for opioid use disorder.
See all our success: ncats.nih.gov/research/our...
April 5, 2025 at 8:06 PM
We've added another success - NUMBER 60 !!! - to our intramural list of FDA drug approvals and clinical trial clearances here at NCATS.
Latest is cross-NIH partnership w/ Amy Newman at NIINDS with IND approved for VK4-116 for opioid use disorder.
See all our success: ncats.nih.gov/research/our...
Latest is cross-NIH partnership w/ Amy Newman at NIINDS with IND approved for VK4-116 for opioid use disorder.
See all our success: ncats.nih.gov/research/our...
Started watching Farscape - I’m not normally a Sci Fi watcher, but liking how it starts:
March 12, 2025 at 2:38 AM
Started watching Farscape - I’m not normally a Sci Fi watcher, but liking how it starts:
So much science happening ; in our NCATS labs we've got a SciEx mass spec screening platform - and we've started HTS on a couple of new methyltransferase targets as part of a collaboration with NCI. The plates are stacking up and loading on to the mass spec as I type .
March 4, 2025 at 3:30 AM
So much science happening ; in our NCATS labs we've got a SciEx mass spec screening platform - and we've started HTS on a couple of new methyltransferase targets as part of a collaboration with NCI. The plates are stacking up and loading on to the mass spec as I type .
Picked this up from X:
Rare diseases have a home at NCATS, was proud to light up Building 1 at the center of the NIH campus in recognition of #RareDiseaseDay. NCATS Director Joni Rutter, DRDRI Director Dominique Pichard are shown. #NIH
Rare diseases have a home at NCATS, was proud to light up Building 1 at the center of the NIH campus in recognition of #RareDiseaseDay. NCATS Director Joni Rutter, DRDRI Director Dominique Pichard are shown. #NIH
February 28, 2025 at 7:02 PM
Picked this up from X:
Rare diseases have a home at NCATS, was proud to light up Building 1 at the center of the NIH campus in recognition of #RareDiseaseDay. NCATS Director Joni Rutter, DRDRI Director Dominique Pichard are shown. #NIH
Rare diseases have a home at NCATS, was proud to light up Building 1 at the center of the NIH campus in recognition of #RareDiseaseDay. NCATS Director Joni Rutter, DRDRI Director Dominique Pichard are shown. #NIH