Charles Ishak
@cishak.bsky.social
Assistant Professor at UT MD Anderson Cancer Center.
Our lab studies transposable elements and viral mimicry in (ovarian) #cancer initiation. #newPI
Lab site: https://www.mdanderson.org/research/departments-labs-institutes/labs/ishak-laboratory.html
Our lab studies transposable elements and viral mimicry in (ovarian) #cancer initiation. #newPI
Lab site: https://www.mdanderson.org/research/departments-labs-institutes/labs/ishak-laboratory.html
Reposted by Charles Ishak
This week, that idea reached patients: Viral-mimicry priming + anti-PD-1 in relapsed/refractory NK/T-cell lymphoma delivered 47.6% complete responses, 66.7% ORR, and ~50% 2-year OS, even after prior PD-1 failure (Huang, Cancer Discovery 2025).
November 7, 2025 at 9:38 PM
This week, that idea reached patients: Viral-mimicry priming + anti-PD-1 in relapsed/refractory NK/T-cell lymphoma delivered 47.6% complete responses, 66.7% ORR, and ~50% 2-year OS, even after prior PD-1 failure (Huang, Cancer Discovery 2025).
Reposted by Charles Ishak
In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers
July 24, 2025 at 3:09 PM
In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers
Congratulations Josh!
July 20, 2025 at 11:24 AM
Congratulations Josh!
Reposted by Charles Ishak
Check out Dr. Mendez-Dorantes' recent preprint for more details on his exciting research! www.biorxiv.org/content/10.1... 42/
Chromosomal rearrangements and instability caused by the LINE-1 retrotransposon
LINE-1 (L1) retrotransposition is widespread in many cancers, especially those with a high burden of chromosomal rearrangements. However, whether and to what degree L1 activity directly impacts genome...
www.biorxiv.org
May 9, 2025 at 2:41 PM
Check out Dr. Mendez-Dorantes' recent preprint for more details on his exciting research! www.biorxiv.org/content/10.1... 42/
Thank you for your support @completegenomics.bsky.social !
April 15, 2025 at 7:57 PM
Thank you for your support @completegenomics.bsky.social !