Christophe Wirth
chriswir.bsky.social
Christophe Wirth
@chriswir.bsky.social
X-ray diffraction data were collected at @esrf.fr on various MX beamlines.

Thanks to
@dfg.de
@uni-freiburg.de
@uniklinik-fr.bsky.social
@cibss.bsky.social
for the funding
January 19, 2026 at 9:05 AM
Happy to share our paper in the frame of the @sfb1453.bsky.social project that got published in @jmolbiol.bsky.social
Tremendous work from @emymrikov.bsky.social and others, on how the scaffold protein PDZK1 interacts with the urate transporter URAT1.
⬇️
www.sciencedirect.com/science/arti...
Molecular Determinants of Selective and High-affinity Binding of the Scaffold Protein PDZK1 to the Urate Transporter URAT1
The renal solute carrier URAT1 (SLC22A12) is essential for urate homeostasis, with loss-of-function linked to renal hypouricemia, nephrolithiasis and …
www.sciencedirect.com
January 16, 2026 at 9:51 AM