Carlos G. Ardanaz
@cgardanaz.bsky.social
Postdoc at @sophiesteculorum.bsky.social lab • @mpi-metabolism.bsky.social | Dazzled by sensory cues.
Reposted by Carlos G. Ardanaz
You are what you eat! Actually, you are also what your mother smelled during pregnancy!🤰
👃smell of high fat diet during #pregnancy primes for #obesity in offspring
Want to know more? Full story here www.nature.com/articles/s42...
Congrats! 👏@sophiesteculorum.bsky.social @lcreimon.bsky.social
👃smell of high fat diet during #pregnancy primes for #obesity in offspring
Want to know more? Full story here www.nature.com/articles/s42...
Congrats! 👏@sophiesteculorum.bsky.social @lcreimon.bsky.social
Fat sensory cues in early life program central response to food and obesity - Nature Metabolism
Non-nutritive sensory components of high-fat diet, such as bacon flavour, are sufficient to impair metabolic health in offspring in mice.
www.nature.com
December 2, 2025 at 7:06 AM
You are what you eat! Actually, you are also what your mother smelled during pregnancy!🤰
👃smell of high fat diet during #pregnancy primes for #obesity in offspring
Want to know more? Full story here www.nature.com/articles/s42...
Congrats! 👏@sophiesteculorum.bsky.social @lcreimon.bsky.social
👃smell of high fat diet during #pregnancy primes for #obesity in offspring
Want to know more? Full story here www.nature.com/articles/s42...
Congrats! 👏@sophiesteculorum.bsky.social @lcreimon.bsky.social
Reposted by Carlos G. Ardanaz
🤩 I’m beyond excited to finally share our paper! 🎉 It’s been a long journey and a true team effort. Congratulations to our outstanding first authors, @lcreimon.bsky.social and Ayden Gouveia, and to all of the co-authors who made this possible 🙌!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Fat sensory cues in early life program central response to food and obesity - Nature Metabolism
Non-nutritive sensory components of high-fat diet, such as bacon flavour, are sufficient to impair metabolic health in offspring in mice.
www.nature.com
December 1, 2025 at 4:30 PM
🤩 I’m beyond excited to finally share our paper! 🎉 It’s been a long journey and a true team effort. Congratulations to our outstanding first authors, @lcreimon.bsky.social and Ayden Gouveia, and to all of the co-authors who made this possible 🙌!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Carlos G. Ardanaz
Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun.
Wonderful list of people: www.thetransmitter.org/early-career...
Wonderful list of people: www.thetransmitter.org/early-career...
November 17, 2025 at 4:46 PM
Thanks @thetransmitter.bsky.social and to my lab for brightening my week with this rising stars in neuroscience award!! Wish I could be in #sfn to celebrate in the sun.
Wonderful list of people: www.thetransmitter.org/early-career...
Wonderful list of people: www.thetransmitter.org/early-career...
Reposted by Carlos G. Ardanaz
I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me!
Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰
Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰
August 15, 2025 at 6:25 PM
I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me!
Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰
Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰
Reposted by Carlos G. Ardanaz
Go ahead and apply to the @cga-age.bsky.social ⚡⚡
We are looking for a PhD student
www.ageing-grad-school.de/phd/host-lab...
We are looking for a PhD student
www.ageing-grad-school.de/phd/host-lab...
August 18, 2025 at 3:39 PM
Go ahead and apply to the @cga-age.bsky.social ⚡⚡
We are looking for a PhD student
www.ageing-grad-school.de/phd/host-lab...
We are looking for a PhD student
www.ageing-grad-school.de/phd/host-lab...
Reposted by Carlos G. Ardanaz
New paper live!
Lots of us assumed that synaptic transmission decreases after energy shortage due to direct neuronal failure. But... Is that the case?
Spoiler: no! It's astrocytes guiding them! ⭐
Check the full study with @maitesolas.bsky.social & others:
www.aginganddisease.org/EN/10.14336/...
Lots of us assumed that synaptic transmission decreases after energy shortage due to direct neuronal failure. But... Is that the case?
Spoiler: no! It's astrocytes guiding them! ⭐
Check the full study with @maitesolas.bsky.social & others:
www.aginganddisease.org/EN/10.14336/...
June 21, 2025 at 11:34 AM
New paper live!
Lots of us assumed that synaptic transmission decreases after energy shortage due to direct neuronal failure. But... Is that the case?
Spoiler: no! It's astrocytes guiding them! ⭐
Check the full study with @maitesolas.bsky.social & others:
www.aginganddisease.org/EN/10.14336/...
Lots of us assumed that synaptic transmission decreases after energy shortage due to direct neuronal failure. But... Is that the case?
Spoiler: no! It's astrocytes guiding them! ⭐
Check the full study with @maitesolas.bsky.social & others:
www.aginganddisease.org/EN/10.14336/...
Reposted by Carlos G. Ardanaz
PAPER ALERT!📣📣
Low brain glucose?
It’s not just neuron starvation.
Astrocytes sense, respond, and regulate synapses.
GLUT1 in astrocytes is a key player in protecting the brain from metabolic stress.
Check out our full study with @cgardanaz.bsky.social
www.aginganddisease.org/EN/10.14336/...
Low brain glucose?
It’s not just neuron starvation.
Astrocytes sense, respond, and regulate synapses.
GLUT1 in astrocytes is a key player in protecting the brain from metabolic stress.
Check out our full study with @cgardanaz.bsky.social
www.aginganddisease.org/EN/10.14336/...
Astrocytic Glucose Sensing Drives Synaptic Depression under Metabolic Stress
<p>Glucose is the primary energy source for the brain, and its continuous supply is essential for neuronal function. Astrocytes play a pivotal role in brain energy metabolism by mediating glucose upta...
www.aginganddisease.org
June 21, 2025 at 10:47 AM
PAPER ALERT!📣📣
Low brain glucose?
It’s not just neuron starvation.
Astrocytes sense, respond, and regulate synapses.
GLUT1 in astrocytes is a key player in protecting the brain from metabolic stress.
Check out our full study with @cgardanaz.bsky.social
www.aginganddisease.org/EN/10.14336/...
Low brain glucose?
It’s not just neuron starvation.
Astrocytes sense, respond, and regulate synapses.
GLUT1 in astrocytes is a key player in protecting the brain from metabolic stress.
Check out our full study with @cgardanaz.bsky.social
www.aginganddisease.org/EN/10.14336/...
Reposted by Carlos G. Ardanaz
This was a really fun project: We blocked obesity in mice by making them do a tiny bit of work for their food. www.sciencedirect.com/science/arti...
A simple action reduces high-fat diet intake and obesity in mice
Diets that are high in fat cause overeating and weight gain in multiple species of animals, suggesting that high dietary fat is sufficient to cause ob…
www.sciencedirect.com
June 19, 2025 at 3:05 PM
This was a really fun project: We blocked obesity in mice by making them do a tiny bit of work for their food. www.sciencedirect.com/science/arti...
Reposted by Carlos G. Ardanaz
Our new preprint: 𝐅𝐞𝐚𝐭𝐮𝐫𝐞-𝐬𝐩𝐞𝐜𝐢𝐟𝐢𝐜 𝐭𝐡𝐫𝐞𝐚𝐭 𝐜𝐨𝐝𝐢𝐧𝐠 𝐢𝐧 𝐥𝐚𝐭𝐞𝐫𝐚𝐥 𝐬𝐞𝐩𝐭𝐮𝐦 𝐠𝐮𝐢𝐝𝐞𝐬 𝐝𝐞𝐟𝐞𝐧𝐬𝐢𝐯𝐞 𝐚𝐜𝐭𝐢𝐨𝐧.
We describe how the LS guides defensive responses by forming critical computations built from functionally and molecularly distinct cells and their afferent inputs.
www.researchsquare.com/article/rs-6...
We describe how the LS guides defensive responses by forming critical computations built from functionally and molecularly distinct cells and their afferent inputs.
www.researchsquare.com/article/rs-6...
Feature-specific threat coding in lateral septum guides defensive action
The ability to rapidly detect and evaluate potential threats is essential for survival and requires the integration of sensory information, with internal state and prior experience. The lateral septum...
www.researchsquare.com
June 16, 2025 at 12:38 PM
Our new preprint: 𝐅𝐞𝐚𝐭𝐮𝐫𝐞-𝐬𝐩𝐞𝐜𝐢𝐟𝐢𝐜 𝐭𝐡𝐫𝐞𝐚𝐭 𝐜𝐨𝐝𝐢𝐧𝐠 𝐢𝐧 𝐥𝐚𝐭𝐞𝐫𝐚𝐥 𝐬𝐞𝐩𝐭𝐮𝐦 𝐠𝐮𝐢𝐝𝐞𝐬 𝐝𝐞𝐟𝐞𝐧𝐬𝐢𝐯𝐞 𝐚𝐜𝐭𝐢𝐨𝐧.
We describe how the LS guides defensive responses by forming critical computations built from functionally and molecularly distinct cells and their afferent inputs.
www.researchsquare.com/article/rs-6...
We describe how the LS guides defensive responses by forming critical computations built from functionally and molecularly distinct cells and their afferent inputs.
www.researchsquare.com/article/rs-6...
Reposted by Carlos G. Ardanaz
📢 🤩Excited to share our latest paper👃🧠! Huge thanks to the amazing first author @janice-bulk.bsky.social and all co-authors, especially @andreas-t-schaefer.bsky.social and @tobiasackels.bsky.social 🙌!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism
The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.
www.nature.com
June 11, 2025 at 11:16 AM
📢 🤩Excited to share our latest paper👃🧠! Huge thanks to the amazing first author @janice-bulk.bsky.social and all co-authors, especially @andreas-t-schaefer.bsky.social and @tobiasackels.bsky.social 🙌!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Carlos G. Ardanaz
My first first-author paper is live - this is amazing!! 🤩
Check it out in Nature Metabolism: www.nature.com/articles/s42...
I can't thank my co-authors and everyone who helped make this happen enough!
@sophiesteculorum.bsky.social @mpi-metabolism.bsky.social
Check it out in Nature Metabolism: www.nature.com/articles/s42...
I can't thank my co-authors and everyone who helped make this happen enough!
@sophiesteculorum.bsky.social @mpi-metabolism.bsky.social
A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism
The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.
www.nature.com
June 11, 2025 at 1:54 PM
My first first-author paper is live - this is amazing!! 🤩
Check it out in Nature Metabolism: www.nature.com/articles/s42...
I can't thank my co-authors and everyone who helped make this happen enough!
@sophiesteculorum.bsky.social @mpi-metabolism.bsky.social
Check it out in Nature Metabolism: www.nature.com/articles/s42...
I can't thank my co-authors and everyone who helped make this happen enough!
@sophiesteculorum.bsky.social @mpi-metabolism.bsky.social
Reposted by Carlos G. Ardanaz
Exciting news from @sophiesteculorum.bsky.social Lab!🤓
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
A food-sensitive olfactory circuit drives anticipatory satiety - Nature Metabolism
The authors describe a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake.
www.nature.com
June 11, 2025 at 3:06 PM
Exciting news from @sophiesteculorum.bsky.social Lab!🤓
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
👃🧠 Smelling food primes your brain for satiety.
Find out more in 🧵 or under 🔗 www.nature.com/articles/s42...
Congrats to @sophiesteculorum.bsky.social , first author @janice-bulk.bsky.social and all contributing authors!
Reposted by Carlos G. Ardanaz
🚨 Paper alert!
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
Obesity dysregulates feeding-evoked response dynamics in hypothalamic satiety neurons
Melanocortin-4 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus (PVHMC4R) integrate hunger-promoting and hunger-suppressing signals to regulate satiety. Food consumption-...
www.biorxiv.org
May 28, 2025 at 8:28 PM
🚨 Paper alert!
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
📣 We found abnormal feeding-related neural responses in satiety-promoting, MC4R-expressing neurons in the mouse paraventricular hypothalamus (PVH-MC4R) following diet-induced obesity. www.biorxiv.org/cgi/content/... #obesity #feedingbehaviour #obesityresearch #neuroscience
Last week I had the pleasure to attend and present a poster at the GRC Modulation of Neural Circuits and Behavior. Unbeatable sharing of science, companionship... and breathtaking venue catalyzing all of it!
May 26, 2025 at 9:01 PM
Last week I had the pleasure to attend and present a poster at the GRC Modulation of Neural Circuits and Behavior. Unbeatable sharing of science, companionship... and breathtaking venue catalyzing all of it!
Reposted by Carlos G. Ardanaz
🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
May 18, 2025 at 8:41 AM
🚨 Preprint alert! 🚨
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
Can mice estimate the distance to an odour source?
New work led by Cristina Marin and colleagues, jointly supervised by @andreas-t-schaefer.bsky.social at the @crick.ac.uk and myself.
Spoiler alert: Yes, they can!
Read the paper here: bit.ly/43A9tF9
Short 🧵 below
First post has to be this:
May 14, 2025 at 10:59 PM
First post has to be this: