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celtliverpool.bsky.social
Centre of Excellence for Long-acting Therapeutics
@celtliverpool.bsky.social
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The Centre of Excellence for Long-acting Therapeutics (CELT) at #livuni is accelerating understanding of #longacting medicines, by combining world leading expertise in pharmacology and materials chemistry to create new interventions.
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celtliverpool.bsky.social
This week's long-acting news from other teams includes:

🫁 Generate:Biomedicines - phase 3 trials of a 6 month asthma treatment
💉@who.int call for rapid expansion of access to new WHO-approved tools to drive down infections on World AIDS Day

Read the full stories
www.liverpool.ac.uk/centre-of-ex...
A person is holding a red AIDS awareness ribbon to the camera.
December 5, 2025 at 2:17 PM
celtliverpool.bsky.social
📣 SPEAKER ANNOUNCEMENT
We're excited to announce the speakers for the first of our new workshop series; LA-LINK
Professor Robert Bies - @ubuffalo.bsky.social
Dr. Harshal Hattyangdi - @liverpooluni.bsky.social
Dr. Catia Marzolini - @unil.bsky.social & @unibas.ch
Dr. @fwojara - Gulu University, Uganda
A picture of each speaker surround the workshop title and information
December 4, 2025 at 12:42 PM
celtliverpool.bsky.social
Our next Community of Practice for long-acting therapeutics for maternal and paediatric health webinar

⭐Designing for the long haul: Lessons for safety studies of long-acting therapeutics from pregnancy through childhood
📆4 February 2026
🗣️Dr Adeniyi Olagunju

www.liverpool.ac.uk/centre-of-ex...
November 26, 2025 at 12:14 PM
celtliverpool.bsky.social
Are you signed up to the quarterly #LONGEVITYproject newsletter?

The international consortium aim to bring long-acting preventatives/treatments to HCV, malaria and TB patients in LMICs, where these diseases have the biggest impact.

Sign up: www.liverpool.ac.uk/centre-of-ex...
@unitaid.bsky.social
A woman looks over the land at the sunrise. Text reads "Subscribe to our mailing list"
November 25, 2025 at 1:02 PM
celtliverpool.bsky.social
20 November is United Nations' #WorldChildrensDay.

How do we advocate for children and keep them safe?

We are actively working on child safety; to prevent malaria, and to create better pathways for children within long-acting clinical research.

Read how:
www.liverpool.ac.uk/centre-of-ex...
An image from the Paediatric Health panel at the first in-person meeting of CELT's Community of Practice. The text reads "How long-acting therapeutics promise to keep children safe"
November 20, 2025 at 12:58 PM
celtliverpool.bsky.social
17-23 November is @worldhepalliance.bsky.social #WorldHepatitisTestingWeek.
We wrote a blog on hepatitis testing as a global issue
The #LONGEVITYproject, is working on a one-shot-cure for HCV to provide patients in LMICs treatment at diagnosis
www.liverpool.ac.uk/centre-of-ex...
@unitaid.bsky.social
An illustration of a hepatitis C virus with the title "Hepatitis Testing Day 2025: Not just a US issue"
November 19, 2025 at 12:19 PM
celtliverpool.bsky.social
📣 We're launching LA-LINK!

A new quarterly online workshop series from researchers, regulators, manufacturers, patient advocates, funders and more.

⭐Application of pharmacokinetic modelling and simulation for long-acting medicines
📆29 January
✅Registration soon

www.liverpool.ac.uk/centre-of-ex...
a chain hangs down with an image of a glowing lightbulb over a global heat map. Text reads "LA-LINK. Application of pharmacokinetic modelling and simulation for long-acting medicines. 29 January 2026, online, the first LA-LINK workshop"
November 18, 2025 at 12:39 PM
celtliverpool.bsky.social
🌟Securing the Future: Shaping the UK Strategy on Long-acting Therapeutics🌟

We were proud to host a collaborative event at the Liver Building, bringing together leaders from industry, academia, NHS, and regulatory bodies to shape the UK’s future long-acting therapeutics strategy.
An upwards shot of the Liver Building in the sunshine Professor Steve Rannard is welcoming the delegates. The slide has the event title written on it. During the conference as delegates sit in their chairs engaging with the presentation. All the delegates are standing outside smiling at the camera. The River Mersey and Wirral are behind them.
November 17, 2025 at 1:23 PM
celtliverpool.bsky.social
This #WorldDiabetesDay, our global long-acting therapeutics news:

💉 ADOCIA: once a month diabetes injection
🔬 SanegeneBio and Innovent: six-monthly hypertension injection
🫀 Rona Therapeutics: reduce ApoC3 and triglycerides

Read more:
www.liverpool.ac.uk/centre-of-ex...
insulin pen, diabetic measurement tools and pills on orange background
November 14, 2025 at 12:39 PM
celtliverpool.bsky.social
A video of our October Community of Practice session is live.

Laxman Cherkupally from @mmv.org delivered the session titled 'Considerations for long-acting injectable microsuspension development - Lessons from an anti-malarial therapy'

Watch here: youtu.be/3PTuh4sfA4g
A flyer with a circle of hands that reads "22/10/25. Community of Practice for long-acting therapeutics in maternal and paediatric health. Webinar: Considerations for long-acting injectable microsuspensions development - Lessons from an anti-malarial therapy."
November 13, 2025 at 12:17 PM
celtliverpool.bsky.social
Calling Clinical Pharmacologists!
Are you keen to make data from published studies count beyond the paper?

PKRxiv is a managed open-access repository and visualization platform for collaborative sharing of anonymised, PK data and associated covariates.
www.liverpool.ac.uk/centre-of-ex...
November 11, 2025 at 12:27 PM
celtliverpool.bsky.social
Managed by @medicinespatentpool.org, LAPaL is a public database providing data on long-acting therapeutics and drug delivery technologies
This month's updates:
Long-acting semaglutide - updated global reg status and clinical trials
Lenacapavir - updated reg status
www.liverpool.ac.uk/centre-of-ex...
The LAPaL logo is the word LAPaL with 'the long-acting therapeutics patents and licences database' underneath.
October 30, 2025 at 3:03 PM
celtliverpool.bsky.social
29 October is @unesco.org's #WorldCodingDay.

It might not be clear how programming helps our goals to save patient lives through long-acting therapeutics, but it's actually a key part of our work.

Find out how in our blog piece:
www.liverpool.ac.uk/centre-of-ex...
Dr Rajith Rajoli is working on some CELT modelling. The blog title is written over the top "Lost on your coding journey? Our pharmacology researchers can help".
October 29, 2025 at 12:31 PM
celtliverpool.bsky.social
'Securing the future: Shaping the UK strategy on long-acting therapeutics' is the first event of the UK Hub for Advanced Long-acting Therapeutics (HALo).

📆 Thursday 6 November 2025
⏰ 10am-4pm
🌍 Liverpool, UK

Find the agenda and how to register: www.liverpool.ac.uk/centre-of-ex...
@ukri.org
An image showing the speakers for the HALo launch. They are: Professor Steve Rannard (HALo), Susan Cole (MHRA), Dr Inti Qurashi (NHS / M-RIC), Dr Christian Seiler (Viiv), Ian Lafferty (Upperton), Henry Dunne (MNS)
October 28, 2025 at 2:13 PM
celtliverpool.bsky.social
Exciting recent long-acting news from other teams includes:

@nhsengland.bsky.social roll out cabotegravir, two monthly HIV PrEP
ViiV show cabotegravir is more acceptable than lenacapavir
FDA approved @tevapharm.bsky.social UZEDY for bipolar I disorder

www.liverpool.ac.uk/centre-of-ex...
A person is reading the news on their tablet
October 24, 2025 at 2:31 PM
celtliverpool.bsky.social
Are you subscribed to our quarterly #LONGEVITYproject newsletter?

We update LONGEVITY news, opportunities and global events.
LONGEVITY, funded by @unitaid.bsky.social, is working to create long-acting malaria, TB and HCV medicines for patients in LMICs.

Sign up: www.liverpool.ac.uk/centre-of-ex...
An illustration of a globe with items leading away from it, they read "materials chemistry + pharmacology + regulatory expertise + community engagement = new long-acting medicines"
October 23, 2025 at 11:53 AM
celtliverpool.bsky.social
Have you used Teoreler for any research that has since been published?

If so, we'd like to add you to the list of publications Teoreler was used for: www.liverpool.ac.uk/centre-of-ex...

Email us on [email protected]
Dr Rajith Rajoli is using modelling software on their computer. Over the image reads "Teoreler: A web-based physiologically based pharmacokinetic (PBPK) modelling application for the simulation and extrapolation of drug use scenarios. This application simulates drug pharmacokinetics of small molecules using complex mathematical equations to predict the efficacy of drugs in the human body in a variety of species and populations."
October 22, 2025 at 11:50 AM
celtliverpool.bsky.social
Dr Cameron Hogarth leads our Manufacturing Capability project, aiming to create an open-access resource of manufacturers' long-acting capabilities in LMICs.

Connecting to organisations is a powerful way to find necessary data.

Read more: www.liverpool.ac.uk/centre-of-ex...
@unitaid.bsky.social
Dr Hogarth is standing outside the conference entrance under a banner that reads "Welcome to AHMTEC 2025"
October 14, 2025 at 11:53 AM
celtliverpool.bsky.social
This #ChildHealthDay we're highlighting our upcoming Community of Practice webinar, hosted by Laxman Cherkupally from @mmv.org on 22 October.

The majority of malaria deaths are children under 5 years old. All malaria work is to protect children health.
events.teams.microsoft.com/event/8ad398...
October 7, 2025 at 11:33 AM
celtliverpool.bsky.social
#ManufacturingDay is the last Thursday of September (UK - @makeuk.bsky.social) and the first Friday of October (US)

We're leading the Manufacturing Capability project to create an open resource to show manufacturing capabilities in LMICs:
www.liverpool.ac.uk/centre-of-ex...
@unitaid.bsky.social
a global heat map with pins has the blog title written over the top: We're a preclinical team with a focus on manufacturing capability - Here's why.
October 3, 2025 at 11:17 AM
celtliverpool.bsky.social
9 October, CELT's Prajith Venkatasubramanian is delivering a webinar with Dr Leena Zino.

They'll discuss long acting drug delivery systems and the patents / regulatory process.

Find out more about this and other events CELT are at via our event page:
www.liverpool.ac.uk/centre-of-ex...
The event title is at the top with pictures of Prajith Venkatasubramanian and Leena Zino with event times underneath them.
October 2, 2025 at 2:35 PM
celtliverpool.bsky.social
The Systems Medicine team have published: Physiologically based pharmacokinetic modelling of serum 25-hydroxyvitamin D concentrations in schoolchildren receiving weekly oral vitamin D3 supplementation

Find a link to the full article and other CELT publications: www.liverpool.ac.uk/centre-of-ex...
A close up image of a vitamin d capsule on a yellow background
October 1, 2025 at 11:35 AM
celtliverpool.bsky.social
Teoreler is a free online PBPK modelling application. With support from @unitaid.bsky.social, our team work really hard to continually update Teoreler and add new models.

Find out more if you're new to Teoreler, or leave us feedback if you're not, via the link: www.liverpool.ac.uk/centre-of-ex...
Dr Rajith Rajoli is using modelling software on their computer. Over the image reads "Teoreler: A web-based physiologically based pharmacokinetic (PBPK) modelling application for the simulation and extrapolation of drug use scenarios. This application simulates drug pharmacokinetics of small molecules using complex mathematical equations to predict the efficacy of drugs in the human body in a variety of species and populations."
September 30, 2025 at 11:02 AM
celtliverpool.bsky.social
28 September was @unesco.org's International Day for Universal Access to Information.

We've told you why we think patients accessing research that represents them is important. Now we can show you how we're doing it.

www.liverpool.ac.uk/centre-of-ex...
#AccessToInfo #AccessToInfoDay #RightToKnow
a group of people are sat in a circle, the text is the blog title "Access to information is mission critical – here’s why and how we’re doing it"
September 29, 2025 at 2:08 PM
celtliverpool.bsky.social
News from other long-acting teams:

- @unitaid.bsky.social, Clinton Health Access Initiative and Wits RHI: agreement with Dr Reddy's Laboratories to make affordable lenacapavir
- @unaids.org respond to the announcement of making affordable HIV preventatives.

www.liverpool.ac.uk/centre-of-ex...
A person is holding a vial of lenacapavir
September 26, 2025 at 11:26 AM