Using this approach, the authors predict and experimentally validate a novel driver of placode development, the transcription factor FOXK2.

Congratulations to all authors!

(4/4)

Integrating this new data with previously published scRNA-seq from the lab, the paper explores dynamics of chromatin accessibility across emerging cell types and infers a gene regulatory network controlling the specification of cranial placodes.

(3/4)

This work led by Eva Hamrud presents a single cell ATAC-seq atlas of the developing chick ectoderm across stages that coincides with the emergence of major cell lineages from the neural plate border.

(2/4)

This paper, published at the Journal of Anatomy, is the third publication this year for PhD Student Ticha, which is a tremendous achievement!

@kingscollegelondon.bsky.social @kingsdentistry.bsky.social

#TMJ
#TemporomandibularJoint
#Fibrocartilage

(3/3)

In the paper authors show that the fibrocartilage of the murine glenoid fossa and condyle of the TMJ are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.

(2/3)

Looking forward the group aims to test whether MMP9 inhibition can be used as a therapeutic for improving muscle function in ageing mammals.

Congratulations to all authors!

Read the paper here: doi.org/10.1111/acel...

(3/3)

First author Dr. Julie Yue Yuan showed MMP9 inhibition acted on inflammatory cells to promote a more effective migratory response of muscle stem cells, resulting in improved muscle repair in telomerase mutants.

(2/3)

This review highlights emerging research that has located progenitor cells in and around the superficial layers of the condyle of the TMJ that can contribute to growth and homeostasis, providing potential targets for regenerative therapies.

#TMJ
#RegenerativeMedicine
#JournalDentalResearch

(3/3)

The temporomandibular joint (TMJ) is a crucial part of our daily lives, playing a role in mastication and communication. Temporomandibular disorders (TMDs) are highly prevalent ( 34%-38% of world population), but therapies are challenging due to the limited self-repair capability of the TMJ.

(2/3)

This study was led by Maricci Basa and recently published at @journalofanatomy.bsky.social
It is a collaboration between Abigail Tucker and @nanthwal.bsky.social at @ccrb27.bsky.social and @rnf.bsky.social at @ucl-c4ia.bsky.social
Congratulations to all authors!

(3/3)

Follow the link below for myth-busting snake ‘chin’ descriptions that will leave your mouth agape 🐍😮

onlinelibrary.wiley.com/doi/10.1111/...

"The wide gape of snakes: A comparison of the developing mandibular symphysis in sauropsids"

#ComparativeAnatomy #Evolution #Snakes #Jaws

(2/3)