Cindy Yeh
@ccindyyeh.bsky.social
Computational biologist at GigaGen | PhD from UW Genome Sciences | desert rat from New Mexico | views my own
First industry publication! Our team developed a high-throughput pooled assay for specificity profiling of antibodies. I’m super grateful to have had the opportunity to contribute to this project www.cell.com/cell-reports...
High-throughput specificity profiling of antibody libraries using ribosome display and microfluidics
Wagner et al. develop PolyMap, a platform that uses ribosome display and single-cell RNA sequencing to screen antibody binding to a library of cell-surface-expressed antigens. Using this system, they map the binding of diverse human donor-derived antibodies to SARS-CoV-2 spike protein variants and further characterize unique clones.
www.cell.com
December 18, 2024 at 1:37 AM
First industry publication! Our team developed a high-throughput pooled assay for specificity profiling of antibodies. I’m super grateful to have had the opportunity to contribute to this project www.cell.com/cell-reports...