@euprojectappeal.bsky.social

Congrats @gaudinlab.bsky.social!

Absolutely stunning! 🤩 Congrats

Thank you @harmitmalik.bsky.social! There are still many aspects of the mechanism at play with the enigmatic MX1 protein that we do not yet understand. Further research needed! ☺️

and last but not least @irim-life.bsky.social @cnrs.fr @umontpellier.bsky.social

Special thanks to great collaborators @sarahgalloism.bsky.social @corentinaube.bsky.social Emiliano Ricci, Manu Labaronne, Nadia Naffakh, Bénédicte Delaval, Raph Gaudin @gaudinlab.bsky.social, our funding agencies @erc.europa.eu @frm-officiel.bsky.social,

Highly collaborative work between Joe and many former and current team members @irim-life.bsky.social: Jimmy Cadènes, Francisco Garcia de Gracia, Mary Arnould, Ana Luiza Chaves Valadão, Marine Tauziet, @arebendenne.bsky.social et @oliviermoncorge.bsky.social.

transiently associates with them, and induces their retrograde transport via dynein and the microtubule network toward a perinuclear region near the microtubule-organizing center (MTOC), where the vRNPs remain sequestered.

Contrary to previous assumptions, we show in this study that the human restriction factor MX1 most potently inhibits human influenza A viruses during the late stages of replication. MX1 appears to sense trafficking viral ribonucleoproteins (vRNPs) en route to the plasma membrane,

Thanks Nate!!!!

congrats Roy!