Carcinogenesis_Oxford Uni Press Journal
@carcin-oxfunipress.bsky.social
Highlighting research published in Carcinogenesis: Integrative Cancer Research - an Oxford University Press journal
https://academic.oup.com/carcin
https://academic.oup.com/carcin
Eighty years of cancer research after the atomic bombings of Hiroshima and Nagasaki
doi.org/10.1093/carc...
doi.org/10.1093/carc...
November 11, 2025 at 5:12 AM
Eighty years of cancer research after the atomic bombings of Hiroshima and Nagasaki
doi.org/10.1093/carc...
doi.org/10.1093/carc...
ONLINE NOW: Special Issue on Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima and Nagasaki
academic.oup.com/carcin/issue...
academic.oup.com/carcin/issue...
November 11, 2025 at 5:08 AM
ONLINE NOW: Special Issue on Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima and Nagasaki
academic.oup.com/carcin/issue...
academic.oup.com/carcin/issue...
Almonertinib enhances radiosensitivity in EGFR-mutant NSCLC via inhibition of EGFR signaling and DNA damage repair
doi.org/10.1093/carc...
doi.org/10.1093/carc...
October 17, 2025 at 2:46 PM
Almonertinib enhances radiosensitivity in EGFR-mutant NSCLC via inhibition of EGFR signaling and DNA damage repair
doi.org/10.1093/carc...
doi.org/10.1093/carc...
The Oncogenic Role of Aurora kinase A in Gastric Cancer: Mechanisms, Pathways and Clinical Relevance
doi.org/10.1093/carc...
doi.org/10.1093/carc...
September 11, 2025 at 10:28 AM
The Oncogenic Role of Aurora kinase A in Gastric Cancer: Mechanisms, Pathways and Clinical Relevance
doi.org/10.1093/carc...
doi.org/10.1093/carc...
Epithelial Ikkβ deletion modulates immune responses and the IFNγ/CXCL9 axis during early esophageal carcinogenesis
doi.org/10.1093/carc...
doi.org/10.1093/carc...
September 9, 2025 at 10:41 AM
Epithelial Ikkβ deletion modulates immune responses and the IFNγ/CXCL9 axis during early esophageal carcinogenesis
doi.org/10.1093/carc...
doi.org/10.1093/carc...
Nobel laureate, molecular biologist & cancer researcher, David Baltimore, died at he age of 87.
shorturl.at/2t7Ya
In 1975, he shared the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, challenging the view that genetic information was only transferred from DNA to RNA
shorturl.at/2t7Ya
In 1975, he shared the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, challenging the view that genetic information was only transferred from DNA to RNA
September 8, 2025 at 7:06 AM
Nobel laureate, molecular biologist & cancer researcher, David Baltimore, died at he age of 87.
shorturl.at/2t7Ya
In 1975, he shared the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, challenging the view that genetic information was only transferred from DNA to RNA
shorturl.at/2t7Ya
In 1975, he shared the Nobel Prize in Physiology or Medicine for discovering reverse transcriptase, challenging the view that genetic information was only transferred from DNA to RNA
Δ133-p53 isoform enhances TLR4 function to promote tumour growth
doi.org/10.1093/carc...
doi.org/10.1093/carc...
September 8, 2025 at 6:29 AM
Δ133-p53 isoform enhances TLR4 function to promote tumour growth
doi.org/10.1093/carc...
doi.org/10.1093/carc...
Mammary Adipose Dysfunction in the Dual Epidemic of Obesity and Breast Cancer
doi.org/10.1093/carc...
doi.org/10.1093/carc...
September 8, 2025 at 6:22 AM
Mammary Adipose Dysfunction in the Dual Epidemic of Obesity and Breast Cancer
doi.org/10.1093/carc...
doi.org/10.1093/carc...
Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima & Nagasaki
In September, Carcinogenesis will publish a special issue to commemorate the 80th anniversary of the atomic bombings in Japan, & our understanding of radiation & its impact on human health
academic.oup.com/carcin
In September, Carcinogenesis will publish a special issue to commemorate the 80th anniversary of the atomic bombings in Japan, & our understanding of radiation & its impact on human health
academic.oup.com/carcin
August 12, 2025 at 5:50 AM
Radiation, Humanity, and Hope: 80 Years of Cancer Research Post-Hiroshima & Nagasaki
In September, Carcinogenesis will publish a special issue to commemorate the 80th anniversary of the atomic bombings in Japan, & our understanding of radiation & its impact on human health
academic.oup.com/carcin
In September, Carcinogenesis will publish a special issue to commemorate the 80th anniversary of the atomic bombings in Japan, & our understanding of radiation & its impact on human health
academic.oup.com/carcin
Longitudinal single-cell RNA model aids prediction of EGFR-TKI resistance
doi.org/10.1093/carc...
The article finds that the molecular mechanisms driving EGFR-TKI resistance in lung cancer may also contribute to poorer prognosis, particularly in lung adenocarcinomas with high EGFR mutation rates.
doi.org/10.1093/carc...
The article finds that the molecular mechanisms driving EGFR-TKI resistance in lung cancer may also contribute to poorer prognosis, particularly in lung adenocarcinomas with high EGFR mutation rates.
August 4, 2025 at 11:23 AM
Longitudinal single-cell RNA model aids prediction of EGFR-TKI resistance
doi.org/10.1093/carc...
The article finds that the molecular mechanisms driving EGFR-TKI resistance in lung cancer may also contribute to poorer prognosis, particularly in lung adenocarcinomas with high EGFR mutation rates.
doi.org/10.1093/carc...
The article finds that the molecular mechanisms driving EGFR-TKI resistance in lung cancer may also contribute to poorer prognosis, particularly in lung adenocarcinomas with high EGFR mutation rates.
Interplay between inflammasomes and PD-1/PD-L1 and their implications in cancer
doi.org/10.1093/carc...
doi.org/10.1093/carc...
June 30, 2025 at 11:03 AM
Interplay between inflammasomes and PD-1/PD-L1 and their implications in cancer
doi.org/10.1093/carc...
doi.org/10.1093/carc...
This study investigated race-specific epigenetic differences in endometrial cancer characteristics & identified subtype-associated CpG differences in genes, including genes regulating cytokine signaling, which were associated with race. doi.org/10.1093/carc...
May 15, 2025 at 9:24 AM
This study investigated race-specific epigenetic differences in endometrial cancer characteristics & identified subtype-associated CpG differences in genes, including genes regulating cytokine signaling, which were associated with race. doi.org/10.1093/carc...
B vitamins and colorectal cancer: exploring research hotspots and frontiers - a bibliometric and visual analysis (1994-2024)
doi.org/10.1093/carc...
doi.org/10.1093/carc...
May 7, 2025 at 8:25 AM
B vitamins and colorectal cancer: exploring research hotspots and frontiers - a bibliometric and visual analysis (1994-2024)
doi.org/10.1093/carc...
doi.org/10.1093/carc...
Genetic determinants & clinical significance of circulating and tumor-specific levels of insulin-like growth factor binding protein 7 in a Swedish breast cancer cohort: doi.org/10.1093/carc... Circulating & genetically predicted IGFBP7 levels are independent prognostic biomarkers in breast cancer.
April 24, 2025 at 10:40 AM
Genetic determinants & clinical significance of circulating and tumor-specific levels of insulin-like growth factor binding protein 7 in a Swedish breast cancer cohort: doi.org/10.1093/carc... Circulating & genetically predicted IGFBP7 levels are independent prognostic biomarkers in breast cancer.
Genetic Susceptibility in Lung Squamous Cell Carcinoma: Data from 3890 LUSC cases and 13328 controls identified an association between 9q33.2 variants and increased risk of LUSC in smokers: doi.org/10.1093/carc...
#lungcancer #LUSC #cancer #genetics #smoking
#lungcancer #LUSC #cancer #genetics #smoking
April 9, 2025 at 10:20 AM
Genetic Susceptibility in Lung Squamous Cell Carcinoma: Data from 3890 LUSC cases and 13328 controls identified an association between 9q33.2 variants and increased risk of LUSC in smokers: doi.org/10.1093/carc...
#lungcancer #LUSC #cancer #genetics #smoking
#lungcancer #LUSC #cancer #genetics #smoking
Multifaceted role of transgelin isoforms in cancer hallmarks
Transgelins regulate actin filament stability & are implicated in carcinogenesis and chemoresistance. This review discusses transgelins as potential cancer biomarkers & oncogenic regulators.
doi.org/10.1093/carc...
Transgelins regulate actin filament stability & are implicated in carcinogenesis and chemoresistance. This review discusses transgelins as potential cancer biomarkers & oncogenic regulators.
doi.org/10.1093/carc...
April 1, 2025 at 9:43 AM
Multifaceted role of transgelin isoforms in cancer hallmarks
Transgelins regulate actin filament stability & are implicated in carcinogenesis and chemoresistance. This review discusses transgelins as potential cancer biomarkers & oncogenic regulators.
doi.org/10.1093/carc...
Transgelins regulate actin filament stability & are implicated in carcinogenesis and chemoresistance. This review discusses transgelins as potential cancer biomarkers & oncogenic regulators.
doi.org/10.1093/carc...
The Influence of Homologous Recombination Repair (HRR) on Temozolomide Chemosensitivity in Glioma. doi.org/10.1093/carc...
This review discusses the role of HRR in temozolomide resistance in glioma, focusing on key HRR factors, including RAD51, ATM & ATR.
This review discusses the role of HRR in temozolomide resistance in glioma, focusing on key HRR factors, including RAD51, ATM & ATR.
March 26, 2025 at 10:01 AM
The Influence of Homologous Recombination Repair (HRR) on Temozolomide Chemosensitivity in Glioma. doi.org/10.1093/carc...
This review discusses the role of HRR in temozolomide resistance in glioma, focusing on key HRR factors, including RAD51, ATM & ATR.
This review discusses the role of HRR in temozolomide resistance in glioma, focusing on key HRR factors, including RAD51, ATM & ATR.
Amlodipine, an L-type Ca2+ channel inhibitor, regulates release of extracellular vesicles from tumor cells & emerges as a potentially promising drug to enhance immunotherapy by inhibiting the production of tumour-derived immunosuppressive exosomes doi.org/10.1093/carc...
March 25, 2025 at 8:56 AM
Amlodipine, an L-type Ca2+ channel inhibitor, regulates release of extracellular vesicles from tumor cells & emerges as a potentially promising drug to enhance immunotherapy by inhibiting the production of tumour-derived immunosuppressive exosomes doi.org/10.1093/carc...
A recent Japanese genome-wide association study identified 5 loci associated with the number of cigarettes smoked per day. This study evaluated whether these loci are associated with lung cancer risk directly or indirectly, through changing smoking behavior: doi.org/10.1093/carc...
March 13, 2025 at 9:48 AM
A recent Japanese genome-wide association study identified 5 loci associated with the number of cigarettes smoked per day. This study evaluated whether these loci are associated with lung cancer risk directly or indirectly, through changing smoking behavior: doi.org/10.1093/carc...
Germline EPHB4R91H mutation as a key player in multiple primary lung tumors doi.org/10.1093/carc...
March 12, 2025 at 9:55 AM
Germline EPHB4R91H mutation as a key player in multiple primary lung tumors doi.org/10.1093/carc...
The current landscape of therapies for hepatocellular carcinoma: doi.org/10.1093/carc...
Primary liver cancer is the third leading cause of cancer-related deaths, accounting for 8.3% of deaths among all cancers. This review discusses the current treatments for early, intermediate, and advanced HCC.
Primary liver cancer is the third leading cause of cancer-related deaths, accounting for 8.3% of deaths among all cancers. This review discusses the current treatments for early, intermediate, and advanced HCC.
March 7, 2025 at 9:00 AM
The current landscape of therapies for hepatocellular carcinoma: doi.org/10.1093/carc...
Primary liver cancer is the third leading cause of cancer-related deaths, accounting for 8.3% of deaths among all cancers. This review discusses the current treatments for early, intermediate, and advanced HCC.
Primary liver cancer is the third leading cause of cancer-related deaths, accounting for 8.3% of deaths among all cancers. This review discusses the current treatments for early, intermediate, and advanced HCC.
Surgical stress induced tumor immune suppressive environment: doi.org/10.1093/carc...
March 6, 2025 at 4:38 AM
Surgical stress induced tumor immune suppressive environment: doi.org/10.1093/carc...
Antibody–drug conjugates (ADCs) in breast cancer: ADCs have made an impact on the treatment of breast cancer. This review summarizes the advances in ADCs in breast cancer patients and explores the challenges and future directions in this field.
doi.org/10.1093/carc...
doi.org/10.1093/carc...
March 6, 2025 at 1:16 AM
Antibody–drug conjugates (ADCs) in breast cancer: ADCs have made an impact on the treatment of breast cancer. This review summarizes the advances in ADCs in breast cancer patients and explores the challenges and future directions in this field.
doi.org/10.1093/carc...
doi.org/10.1093/carc...
Special issue on the latest advances and challenges in pancreatic cancer research in memory of S. Perwez Hussain
academic.oup.com/carcin/issue...
including: CAFomics: convergence to translation for precision stroma approaches
academic.oup.com/carcin/issue...
including: CAFomics: convergence to translation for precision stroma approaches
March 1, 2025 at 1:00 AM
Special issue on the latest advances and challenges in pancreatic cancer research in memory of S. Perwez Hussain
academic.oup.com/carcin/issue...
including: CAFomics: convergence to translation for precision stroma approaches
academic.oup.com/carcin/issue...
including: CAFomics: convergence to translation for precision stroma approaches
Allura Red AC is a xenobiotic. Is it also a carcinogen?
doi.org/10.1093/carc...
doi.org/10.1093/carc...
March 1, 2025 at 12:53 AM
Allura Red AC is a xenobiotic. Is it also a carcinogen?
doi.org/10.1093/carc...
doi.org/10.1093/carc...