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bushlab.bsky.social
Bush Lab
@bushlab.bsky.social
The Bush Lab is a research group at the University of Washington in Seattle. We advance mass spectrometry for biophysics and structural biology. https://biophysicalms.org/
Thanks for highlighting! I'm going to share a set of nice photos that I'll make available for teaching. My aspirational plan is to write questions for each artifact (like those for the QTOF), but I ran out of time before the workshop. I'll also post photos to bsky and crowd source ideas!
November 5, 2025 at 4:12 PM
I've only witnessed it once before, but it left an indelible mark on my soul. Required extensive cleaning of two chambers and replacement of ion guides. There are ways to avoid this outcome (backfilling with nitrogen and closing valves.) For our research, I will continue usin oil free pumps.
November 4, 2025 at 6:20 AM
Past award recipients: www.acs.org/funding/awar...
Past Recipients - American Chemical Society
American Chemical Society: Chemistry for Life.
www.acs.org
November 1, 2025 at 4:39 PM
November 1, 2025 at 4:34 PM
I will cite this paper more going forward. What happened with the original submission? @goodlettlabb.bsky.social name appears correct in the PDF from 1994 - was the incorrect spelling submitted to Chemical Abstract Services or the like?
October 21, 2025 at 6:52 PM
Calculating the COM collision energy under those conditions sounds like a great question for a problem set! Thanks for sharing.
October 3, 2025 at 2:50 AM
Congratulations to AnneClaire Wageman, Addison Roush, and Bruce Feng! SLIMPHONY is enabling exciting new research that we look forward to reporting in the months and years ahead.
September 26, 2025 at 11:59 PM
A fuse or breaker on the instrument should pop before the breaker in the panel. None of these systems are infallible, so the breaker mitigates worst case scenarios (eg, electrical fire). I have run systems as you are proposing (15A system on 20A or 30A circuit), but I try to correct that situation.
August 11, 2025 at 4:41 PM
A mass spectrometer should be on its own circuit (i.e., a dedicated breaker). Swapping to a lower amp breaker on an existing circuit is easy (say 2-5 minutes), but usually requires powering off the entire panel. If you have the electrician save the original breaker, also easy to revert.
August 11, 2025 at 4:26 PM
I think it is worth having an electrician swap out the 30 A breaker for a 15 A breaker. Should be very low cost (<$100, even at university). If something goes really wrong (bearings sieze on pump, arcing on control board), the correct breaker will help manage the severity).
August 11, 2025 at 5:59 AM
In USA, another aspect is single phase versus three phase for 208 V.
August 11, 2025 at 5:54 AM
Sadly, the NSF MRI program is not accepting proposals this year. Hopefully this is only a one-year interruption to this program, which is critical to building the infrastructure to train scientist and engineers in the United States. www.nsf.gov/funding/oppo... | www.nsf.gov/funding/oppo...
www.nsf.gov
August 5, 2025 at 4:36 PM
Track records for using and sustaining instruments are evaluated carefully during proposal review. The program seeks to support long-term, stable, and sustainable instruments for research. A major concern is the possibility of instruments falling out of operation after initial service contract.
August 5, 2025 at 4:36 PM
Interested in acquiring mass spectrometers through the NSF MRI program? @jaygforsythe.bsky.social greatly strengthened his proposal by reporting heavy use of a functionally obsolete system (RIP Voyager) that he sustained by "replac[ing] a few parts (turbo pump, ion gauges, vacuum control box)."
August 5, 2025 at 4:36 PM