Christian Broberger
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broberger.bsky.social
Christian Broberger
@broberger.bsky.social
Neuroscientist at Stockholm University. 🧠. Our lab studies the neural network basis of innate behaviours, and structure-function relationships in oscillating brain circuits. All views my own. ”Of physiology from top to toe I sing”/W. Whitman.
Grattis - välförtjänt! ❤️🇺🇦
November 28, 2025 at 12:33 PM
How wonderful, Catherine! What a great and appropriate honour. 🌟
October 29, 2025 at 9:22 PM
16/n. This work @stockholm-uni.bsky.social was generously funded by @kawresearch.bsky.social and @vetenskapsradet.bsky.social w/ support to the lab also from @erc.europa.eu. If you like this study: first-author Stefanos Stagkourakis has just opened his own lab at SciLifeLabs/Karolinska Institutet.
October 5, 2025 at 6:02 PM
15/n. …With the sudden appearance of an intruder, activation of these cells may serve to prioritize attack over nursing to direct attention and resources towards the most imminent threat to the pups’ survival.
October 5, 2025 at 6:02 PM
14/n. We propose a model in which PMvDAT neurons are hormonally primed into a hyperexcitable state in the dam, greatly lowering the threshold for eliciting attacks against conspecifics…
October 5, 2025 at 6:02 PM
13/n. To our surprise, this intervention dramatically disrupted pup care (without eliciting any attacks toward the pups); retrieval failed almost completely.
October 5, 2025 at 6:02 PM
12/n. Finally, we wondered if PMvDAT cells can also activate other components of the maternal behavioural repertoire, a question we addressed by opto-activating these neurons system during a pup retrieval test, i.e. in the •absence• of an adult intruder.
October 5, 2025 at 6:02 PM
11/n. So some, as yet unidentified, factor, likely operating during pregnancy, seems to be a required switch to facilitate the attack mode in dams.
October 5, 2025 at 6:02 PM
10/n. However, there’s definitely more to maternal aggression than the rise of prolactin and oxytocin post-partum. We were not able to trigger aggression in virgin females by infusing the hormones, separately or in cocktail, into the PMv.
October 5, 2025 at 6:02 PM
9/n. Patch clamp recordings from PMvDAT neurons showed that prolactin powerfully excites these cells through a multitude of mechanisms. Similarly, oxytocin had a strong depolarizing action on PMvDAT neurons.
October 5, 2025 at 6:02 PM