Britta Velten
@brittavelten.bsky.social
Tenure-Track-Professor for Multifactorial Data Analysis and Machine Learning in the Life Sciences @UniHeidelberg
https://velten-group.org/
https://velten-group.org/
Take a look at the data yourself in our interactive browser www.sanger.ac.uk/tool/crispri... and read our paper for lessons learnt on the design of population- and genome scale CRISPR screens
CRISPRi + scRNA-seq + HIPSCI
Large-scale CRISPRi screens with scRNA-seq read-out in iPSCs
www.sanger.ac.uk
December 3, 2025 at 9:17 AM
Take a look at the data yourself in our interactive browser www.sanger.ac.uk/tool/crispri... and read our paper for lessons learnt on the design of population- and genome scale CRISPR screens
With @leopoldparts.bsky.social and @oliverstegle.bsky.social we comprehensively mapped CRISPRi responses in iPSCs identifying protein complexes as nexus for transcriptional changes and made a first step towards population-scale CRISPR screens to dissect genetic modulation of perturbation responses
December 3, 2025 at 9:17 AM
With @leopoldparts.bsky.social and @oliverstegle.bsky.social we comprehensively mapped CRISPRi responses in iPSCs identifying protein complexes as nexus for transcriptional changes and made a first step towards population-scale CRISPR screens to dissect genetic modulation of perturbation responses