Marco Breinig
@breinigmarco.bsky.social
*The necessity and power of random, under-sampled experiments in biology...
*🍫-🐭, PERTURB-CAST, RUBIX...
*🍫-🐭, PERTURB-CAST, RUBIX...
Reposted by Marco Breinig
By enabling exploration of a combinatorial perturbation space that approaches the diversity accessed by natural evolution, CRISPR All opens new possibilities for both biological discovery and therapeutic design.
Learn more in the preprint: www.biorxiv.org/content/10.1...
Learn more in the preprint: www.biorxiv.org/content/10.1...
A unified genetic perturbation language for human cellular programming
Evolution simultaneously and combinatorially explores complex genetic changes across perturbation classes, including gene knockouts, knockdowns, overexpression, and the creation of new genes from exis...
www.biorxiv.org
November 20, 2025 at 6:35 PM
By enabling exploration of a combinatorial perturbation space that approaches the diversity accessed by natural evolution, CRISPR All opens new possibilities for both biological discovery and therapeutic design.
Learn more in the preprint: www.biorxiv.org/content/10.1...
Learn more in the preprint: www.biorxiv.org/content/10.1...