Bork Group at EMBL Heidelberg
@borklab.bsky.social
Computational biology lab focusing on microbiomes in the human gut and the environment
Homepage: https://www.bork.embl.de/
Mastodon: https://mstdn.science/@BorkLab
Homepage: https://www.bork.embl.de/
Mastodon: https://mstdn.science/@BorkLab
Reposted by Bork Group at EMBL Heidelberg
We're up to 1000 studies in metalog.embl.de ! For the past year the focus was on finding inconsistencies in the data and creating the website, but now I have more time to go through the backlog of annotated issues to do QC and load them into the database.
November 6, 2025 at 2:55 PM
We're up to 1000 studies in metalog.embl.de ! For the past year the focus was on finding inconsistencies in the data and creating the website, but now I have more time to go through the backlog of annotated issues to do QC and load them into the database.
Reposted by Bork Group at EMBL Heidelberg
Great to see this finally published!
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
Abstract. Metagenomic sequencing enables the in-depth study of microbes and their functions in humans, animals, and the environment. While sequencing data
academic.oup.com
October 31, 2025 at 3:16 PM
Great to see this finally published!
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Metalog: curated and harmonised contextual data for global metagenomics samples
now out in @narjournal.bsky.social
academic.oup.com/nar/advance-...
Our newest preprint is the work of two talented PhD students: Dominic Eriksson (working in the labs of Meike Vogt, Nicolas Gruber & Shinichi Sunagawa @ethz.ch) and @jonas-bio.bsky.social from our group @embl.org, investigating latitudinal diversity gradients of the ocean microbiome (🧵 linked below)
Latitudinal diversity gradients (LDGs) are found across 🌱🐨🦠 but their underlying mechanisms remain unclear.
In this study, we highlight that LDGs are not universal in marine microbiomes but reflect lineage-specific ecological strategies and environmental responses.
doi.org/10.1101/2025...
In this study, we highlight that LDGs are not universal in marine microbiomes but reflect lineage-specific ecological strategies and environmental responses.
doi.org/10.1101/2025...
Variations in the latitudinal diversity gradients of the ocean microbiome
Latitudinal diversity gradients (LDGs), typically declining from the equator to the poles, are among the most pervasive macroecological patterns, yet their generality and underlying drivers in the oce...
doi.org
October 15, 2025 at 1:23 PM
Our newest preprint is the work of two talented PhD students: Dominic Eriksson (working in the labs of Meike Vogt, Nicolas Gruber & Shinichi Sunagawa @ethz.ch) and @jonas-bio.bsky.social from our group @embl.org, investigating latitudinal diversity gradients of the ocean microbiome (🧵 linked below)
Reposted by Bork Group at EMBL Heidelberg
Latitudinal diversity gradients (LDGs) are found across 🌱🐨🦠 but their underlying mechanisms remain unclear.
In this study, we highlight that LDGs are not universal in marine microbiomes but reflect lineage-specific ecological strategies and environmental responses.
doi.org/10.1101/2025...
In this study, we highlight that LDGs are not universal in marine microbiomes but reflect lineage-specific ecological strategies and environmental responses.
doi.org/10.1101/2025...
Variations in the latitudinal diversity gradients of the ocean microbiome
Latitudinal diversity gradients (LDGs), typically declining from the equator to the poles, are among the most pervasive macroecological patterns, yet their generality and underlying drivers in the oce...
doi.org
October 15, 2025 at 12:05 PM
Latitudinal diversity gradients (LDGs) are found across 🌱🐨🦠 but their underlying mechanisms remain unclear.
In this study, we highlight that LDGs are not universal in marine microbiomes but reflect lineage-specific ecological strategies and environmental responses.
doi.org/10.1101/2025...
In this study, we highlight that LDGs are not universal in marine microbiomes but reflect lineage-specific ecological strategies and environmental responses.
doi.org/10.1101/2025...
Reposted by Bork Group at EMBL Heidelberg
The Data Science team at EMBL is hiring for two open positions! First, for a Scientific Community Manager, focusing on community aspects and training on data science. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Scientific Community Manager
EMBL is Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation with more than 110 independent research groups and teams performing scientific research in disci...
embl.wd103.myworkdayjobs.com
October 8, 2025 at 7:08 AM
The Data Science team at EMBL is hiring for two open positions! First, for a Scientific Community Manager, focusing on community aspects and training on data science. embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
Reposted by Bork Group at EMBL Heidelberg
Had a great time yesterday presenting my efforts to use large-scale computational analyses to better understand marine microbes and their impact on carbon cycling. Thanks #SAME18 for the opportunity!
September 30, 2025 at 1:16 PM
Had a great time yesterday presenting my efforts to use large-scale computational analyses to better understand marine microbes and their impact on carbon cycling. Thanks #SAME18 for the opportunity!
Reposted by Bork Group at EMBL Heidelberg
Our scientific organisers opened ‘The human microbiome’ symposium by giving us a brief update on their most recent work 🦠 #EESMicrobiome
🔹Mani Arumugam, University of Copenhagen
🔹Ami Bhatt, Stanford University School of Medicine
🔹Peer Bork, EMBL Heidelberg
🔹Nicola Segata, University of Trento
🔹Mani Arumugam, University of Copenhagen
🔹Ami Bhatt, Stanford University School of Medicine
🔹Peer Bork, EMBL Heidelberg
🔹Nicola Segata, University of Trento
September 16, 2025 at 3:11 PM
Our scientific organisers opened ‘The human microbiome’ symposium by giving us a brief update on their most recent work 🦠 #EESMicrobiome
🔹Mani Arumugam, University of Copenhagen
🔹Ami Bhatt, Stanford University School of Medicine
🔹Peer Bork, EMBL Heidelberg
🔹Nicola Segata, University of Trento
🔹Mani Arumugam, University of Copenhagen
🔹Ami Bhatt, Stanford University School of Medicine
🔹Peer Bork, EMBL Heidelberg
🔹Nicola Segata, University of Trento
New preprint from lab: www.biorxiv.org/content/10.1... describing the Metalog database of manually annotated contextual data for >110k metagenomics samples around the globe metalog.embl.de
See the thread below from @biocs.bsky.social for more info!
See the thread below from @biocs.bsky.social for more info!
August 15, 2025 at 8:11 AM
New preprint from lab: www.biorxiv.org/content/10.1... describing the Metalog database of manually annotated contextual data for >110k metagenomics samples around the globe metalog.embl.de
See the thread below from @biocs.bsky.social for more info!
See the thread below from @biocs.bsky.social for more info!
Reposted by Bork Group at EMBL Heidelberg
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
August 7, 2025 at 8:28 AM
We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.
Take a look at these four open positions 👇
Reposted by Bork Group at EMBL Heidelberg
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Group Leader – Molecular Systems Biology Unit
Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...
embl.wd103.myworkdayjobs.com
July 30, 2025 at 3:15 PM
Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!
Reposted by Bork Group at EMBL Heidelberg
We're hiring a postdoc!🚨
Study human-associated microbial communities in health & disease.
🔬Requirements:
- PhD in bioinformatics, microbiology, or related field
- Expertise in omics data analysis
- Micro & molecular bio techniques are a plus!
Apply now!🌟
jobs.vib.be/j/119682/pos...
Study human-associated microbial communities in health & disease.
🔬Requirements:
- PhD in bioinformatics, microbiology, or related field
- Expertise in omics data analysis
- Micro & molecular bio techniques are a plus!
Apply now!🌟
jobs.vib.be/j/119682/pos...
Postdoctoral position in human gut microbiome and bioinformatics - VIB
About the Lab
Thelab of JeroenRaes(VIB, KU Leuven) is home to a vibrant, dynamic and international group of researchers in the field of gut microbial ecology and its
jobs.vib.be
July 23, 2025 at 6:43 AM
We're hiring a postdoc!🚨
Study human-associated microbial communities in health & disease.
🔬Requirements:
- PhD in bioinformatics, microbiology, or related field
- Expertise in omics data analysis
- Micro & molecular bio techniques are a plus!
Apply now!🌟
jobs.vib.be/j/119682/pos...
Study human-associated microbial communities in health & disease.
🔬Requirements:
- PhD in bioinformatics, microbiology, or related field
- Expertise in omics data analysis
- Micro & molecular bio techniques are a plus!
Apply now!🌟
jobs.vib.be/j/119682/pos...
At #ISMBECCB2025, @agrekova.bsky.social will present her recent work on detecting mobile genetic elements in both reference and metagenome-assembled genomes in the Microbiome track on Thursday at 3 pm. Come for a sneak peek of the content in promge.embl.de version 2 (to be released in ~1 month)!
proMGE
promge.embl.de
July 22, 2025 at 7:08 AM
At #ISMBECCB2025, @agrekova.bsky.social will present her recent work on detecting mobile genetic elements in both reference and metagenome-assembled genomes in the Microbiome track on Thursday at 3 pm. Come for a sneak peek of the content in promge.embl.de version 2 (to be released in ~1 month)!
Reposted by Bork Group at EMBL Heidelberg
Our new preprint is out!
www.biorxiv.org/content/10.1...
In this study, we present the largest systematic analysis of microbiome structure and function, integrating 85K uniformly processed metagenomes from diverse habitats worldwide.
@podlesny.bsky.social @jonas-bio.bsky.social @borklab.bsky.social
www.biorxiv.org/content/10.1...
In this study, we present the largest systematic analysis of microbiome structure and function, integrating 85K uniformly processed metagenomes from diverse habitats worldwide.
@podlesny.bsky.social @jonas-bio.bsky.social @borklab.bsky.social
Planetary microbiome structure and generalist-driven gene flow across disparate habitats
Microbes are ubiquitous on Earth, forming microbiomes that sustain macroscopic life and biogeochemical cycles. Microbial dispersion, driven by natural processes and human activities, interconnects mic...
www.biorxiv.org
July 21, 2025 at 11:56 AM
Our new preprint is out!
www.biorxiv.org/content/10.1...
In this study, we present the largest systematic analysis of microbiome structure and function, integrating 85K uniformly processed metagenomes from diverse habitats worldwide.
@podlesny.bsky.social @jonas-bio.bsky.social @borklab.bsky.social
www.biorxiv.org/content/10.1...
In this study, we present the largest systematic analysis of microbiome structure and function, integrating 85K uniformly processed metagenomes from diverse habitats worldwide.
@podlesny.bsky.social @jonas-bio.bsky.social @borklab.bsky.social
New preprint from the lab: "Planetary microbiome structure and generalist-driven gene flow across disparate habitats" analysing 85k metagenomes across the world, e.g. looking into generalism across habitats www.biorxiv.org/content/10.1... – see the thread below for more details!
#MicroSky 🖥️🧬🦠
#MicroSky 🖥️🧬🦠
Our new preprint is out!
www.biorxiv.org/content/10.1...
In this study, we present the largest systematic analysis of microbiome structure and function, integrating 85K uniformly processed metagenomes from diverse habitats worldwide.
@podlesny.bsky.social @jonas-bio.bsky.social @borklab.bsky.social
www.biorxiv.org/content/10.1...
In this study, we present the largest systematic analysis of microbiome structure and function, integrating 85K uniformly processed metagenomes from diverse habitats worldwide.
@podlesny.bsky.social @jonas-bio.bsky.social @borklab.bsky.social
Planetary microbiome structure and generalist-driven gene flow across disparate habitats
Microbes are ubiquitous on Earth, forming microbiomes that sustain macroscopic life and biogeochemical cycles. Microbial dispersion, driven by natural processes and human activities, interconnects mic...
www.biorxiv.org
July 21, 2025 at 1:57 PM
New preprint from the lab: "Planetary microbiome structure and generalist-driven gene flow across disparate habitats" analysing 85k metagenomes across the world, e.g. looking into generalism across habitats www.biorxiv.org/content/10.1... – see the thread below for more details!
#MicroSky 🖥️🧬🦠
#MicroSky 🖥️🧬🦠
Reposted by Bork Group at EMBL Heidelberg
TREC is hiring! @embl.org is looking for a field technician/engineer to coordinate soil sampling: plan activities, apply protocols, lead site scouting, coordinate teams & more. Join an amazing international team exploring a hidden universe beneath our feet. Please spread the word! bit.ly/4eSTPbZ
Environmental Technician or Engineer (Soil Lead)
The European Molecular Biology Laboratory (EMBL) is Europe’s flagship research institution for the life sciences, bringing together over 110 independent research groups and service teams across six si...
bit.ly
July 16, 2025 at 1:11 PM
TREC is hiring! @embl.org is looking for a field technician/engineer to coordinate soil sampling: plan activities, apply protocols, lead site scouting, coordinate teams & more. Join an amazing international team exploring a hidden universe beneath our feet. Please spread the word! bit.ly/4eSTPbZ
Reposted by Bork Group at EMBL Heidelberg
Very cool. Here, authors did pairwise co-culturing (mGAM/anaerobiosis) of 97 gut microbial species (113 strains) to infer ecological interactions (n=3233). Most negative were between distant taxa & positive were more among low-abundance taxa.
🔗 microbiomejournal.biomedcentral.com/articles/10....
🔗 microbiomejournal.biomedcentral.com/articles/10....
Systematic pairwise co-cultures uncover predominant negative interactions among human gut bacteria - Microbiome
Background Understanding pairwise bacterial interactions in the human gut is crucial for deciphering the complex networks of bacterial interactions and their contributions to host health. However, the...
microbiomejournal.biomedcentral.com
July 16, 2025 at 3:05 PM
Very cool. Here, authors did pairwise co-culturing (mGAM/anaerobiosis) of 97 gut microbial species (113 strains) to infer ecological interactions (n=3233). Most negative were between distant taxa & positive were more among low-abundance taxa.
🔗 microbiomejournal.biomedcentral.com/articles/10....
🔗 microbiomejournal.biomedcentral.com/articles/10....
Reposted by Bork Group at EMBL Heidelberg
It's finally out!🎉
We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠
So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...
We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠
So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...
www.nature.com
July 16, 2025 at 3:04 PM
It's finally out!🎉
We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠
So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...
We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠
So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...
Reposted by Bork Group at EMBL Heidelberg
The team's first preprint is out!
Led by
@vishnuprasoodanan.bsky.social & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data?
A 🧵.
Led by
@vishnuprasoodanan.bsky.social & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data?
A 🧵.
A census of hidden and discoverable microbial diversity beyond genome-centric approaches https://www.biorxiv.org/content/10.1101/2025.06.26.661807v1
June 27, 2025 at 8:10 PM
The team's first preprint is out!
Led by
@vishnuprasoodanan.bsky.social & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data?
A 🧵.
Led by
@vishnuprasoodanan.bsky.social & @omaistrenko.bsky.social , we asked a question (almost) as old as microbiology: how many prokaryotic species exist on Earth? More specifically, how much diversity is "hiding" in existing metagenomic data?
A 🧵.
Reposted by Bork Group at EMBL Heidelberg
After a long silence on X (for obvious reasons), the Zeller Lab is now on Bluesky! We’ll post updates soon on what’s been happening in the lab over the past few months. For the future, we promise to share our News in a more timely manner here on this channel.
#Microbiome #Bioinformatics #ZellerLab
#Microbiome #Bioinformatics #ZellerLab
June 26, 2025 at 11:41 AM
After a long silence on X (for obvious reasons), the Zeller Lab is now on Bluesky! We’ll post updates soon on what’s been happening in the lab over the past few months. For the future, we promise to share our News in a more timely manner here on this channel.
#Microbiome #Bioinformatics #ZellerLab
#Microbiome #Bioinformatics #ZellerLab
Reposted by Bork Group at EMBL Heidelberg
📥 You have only until 24 June to submit your abstract for 'The human microbiome'❗
🔬💊 Explore cutting-edge breakthroughs in #microbiome research, from methodological innovations to integrative approaches and personalised therapeutics. Join #EESMicrobiome 🦠🔍
➡️ https://s.embl.org/ees25-08-bl
🔬💊 Explore cutting-edge breakthroughs in #microbiome research, from methodological innovations to integrative approaches and personalised therapeutics. Join #EESMicrobiome 🦠🔍
➡️ https://s.embl.org/ees25-08-bl
June 16, 2025 at 8:20 AM
📥 You have only until 24 June to submit your abstract for 'The human microbiome'❗
🔬💊 Explore cutting-edge breakthroughs in #microbiome research, from methodological innovations to integrative approaches and personalised therapeutics. Join #EESMicrobiome 🦠🔍
➡️ https://s.embl.org/ees25-08-bl
🔬💊 Explore cutting-edge breakthroughs in #microbiome research, from methodological innovations to integrative approaches and personalised therapeutics. Join #EESMicrobiome 🦠🔍
➡️ https://s.embl.org/ees25-08-bl
Reposted by Bork Group at EMBL Heidelberg
Join us at #EESMicrobiome!
Organisers Mani Arumugam (#uni_copenhagen), Ami Bhatt (@stanfordpress.bsky.social), Peer Bork (@borklab.bsky.social) and Nicola Segata (#CIBIO_UniTrento) look forward to welcoming #microbiome scientists in September at @embl.org!
@events.embl.org
Organisers Mani Arumugam (#uni_copenhagen), Ami Bhatt (@stanfordpress.bsky.social), Peer Bork (@borklab.bsky.social) and Nicola Segata (#CIBIO_UniTrento) look forward to welcoming #microbiome scientists in September at @embl.org!
@events.embl.org
June 6, 2025 at 10:36 AM
Join us at #EESMicrobiome!
Organisers Mani Arumugam (#uni_copenhagen), Ami Bhatt (@stanfordpress.bsky.social), Peer Bork (@borklab.bsky.social) and Nicola Segata (#CIBIO_UniTrento) look forward to welcoming #microbiome scientists in September at @embl.org!
@events.embl.org
Organisers Mani Arumugam (#uni_copenhagen), Ami Bhatt (@stanfordpress.bsky.social), Peer Bork (@borklab.bsky.social) and Nicola Segata (#CIBIO_UniTrento) look forward to welcoming #microbiome scientists in September at @embl.org!
@events.embl.org
Reposted by Bork Group at EMBL Heidelberg
This is just an excellent preprint by Rasmus Jensen and colleagues from Julia Mahamid's lab @embl.org - a tour de force of Cryogenic electron tomography to do in cell structural biology in which they discover a new complex and solve its structure and function! www.biorxiv.org/content/10.1...
In-cell discovery and characterization of a non-canonical bacterial protein translocation-folding complex
Cryo-electron tomography has emerged as powerful technology for in-cell structural biology, and in combination with breakthroughs in protein structure prediction, offers a unique opportunity for illum...
www.biorxiv.org
May 22, 2025 at 7:01 PM
This is just an excellent preprint by Rasmus Jensen and colleagues from Julia Mahamid's lab @embl.org - a tour de force of Cryogenic electron tomography to do in cell structural biology in which they discover a new complex and solve its structure and function! www.biorxiv.org/content/10.1...
Reposted by Bork Group at EMBL Heidelberg
Open postdoc position in my lab @earlhaminst.bsky.social @quadraminstitute.bsky.social
We will generate large-scale soil metagenomes to research the impact of agriculture on healthy soil microbiomes, developing strategies to increase carbon retention: jobs.earlham.ac.uk/Details.asp?...
Please RT
We will generate large-scale soil metagenomes to research the impact of agriculture on healthy soil microbiomes, developing strategies to increase carbon retention: jobs.earlham.ac.uk/Details.asp?...
Please RT
May 7, 2025 at 5:23 PM
Open postdoc position in my lab @earlhaminst.bsky.social @quadraminstitute.bsky.social
We will generate large-scale soil metagenomes to research the impact of agriculture on healthy soil microbiomes, developing strategies to increase carbon retention: jobs.earlham.ac.uk/Details.asp?...
Please RT
We will generate large-scale soil metagenomes to research the impact of agriculture on healthy soil microbiomes, developing strategies to increase carbon retention: jobs.earlham.ac.uk/Details.asp?...
Please RT
Reposted by Bork Group at EMBL Heidelberg
Live in 2h: Metagenomic microbial strain tracking in the cloud! I'll be doing a quick demo showing how to use the SameStr workflow on the @nfdi4microbiota.bsky.social Cloud-based Workflow Platform (CloWM) - GUI / no-install / scalable / free for scientific use.
Join our next Coffee Talk on 28 April at 14:30 CEST!
@podlesny.bsky.social (EMBL) presents SameStr—a new tool for strain-resolved metagenomics. Track microbes with high precision.
🔗 Zoom: ID 687 6408 9023 | PW: 826218
#Microbiome #Metagenomics #OpenScience
@podlesny.bsky.social (EMBL) presents SameStr—a new tool for strain-resolved metagenomics. Track microbes with high precision.
🔗 Zoom: ID 687 6408 9023 | PW: 826218
#Microbiome #Metagenomics #OpenScience
April 28, 2025 at 10:21 AM
Live in 2h: Metagenomic microbial strain tracking in the cloud! I'll be doing a quick demo showing how to use the SameStr workflow on the @nfdi4microbiota.bsky.social Cloud-based Workflow Platform (CloWM) - GUI / no-install / scalable / free for scientific use.
Reposted by Bork Group at EMBL Heidelberg
Two years ago, TREC began in Roscoff. Sampling at 120+ sites across Europe was supported by @embl.org custom-built mobile lab and @taraoceans-science.bsky.social schooner, enabling on-site processing across land and sea. Now this work continues, with 100s of projects initiated 📸 Kinga Lubowiecka
April 10, 2025 at 7:12 AM
Two years ago, TREC began in Roscoff. Sampling at 120+ sites across Europe was supported by @embl.org custom-built mobile lab and @taraoceans-science.bsky.social schooner, enabling on-site processing across land and sea. Now this work continues, with 100s of projects initiated 📸 Kinga Lubowiecka