Ran Blekhman
@blekhman.bsky.social
Professor of Medicine at the University of Chicago. Decoding the human microbiome. http://BlekhmanLab.org
Seriously someone should write about the scientific evidence supporting the alleged health benefits of each of these items - I bet it's 99% nonsense
November 21, 2025 at 11:21 PM
Seriously someone should write about the scientific evidence supporting the alleged health benefits of each of these items - I bet it's 99% nonsense
Yes -- this is actually the same parallel the authors use in the review!
November 20, 2025 at 5:18 PM
Yes -- this is actually the same parallel the authors use in the review!
Our contribution to this special issue: a review on data analysis of human gut microbiome data from global populations
www.cell.com/trends/micro...
www.cell.com/trends/micro...
Analyzing human gut microbiome data from global populations: challenges and resources
Research on the human gut microbiome is expanding rapidly; yet, most published studies
focus on populations from high-income regions such as North America and Europe. Underrepresentation
of population...
www.cell.com
November 12, 2025 at 2:13 AM
Our contribution to this special issue: a review on data analysis of human gut microbiome data from global populations
www.cell.com/trends/micro...
www.cell.com/trends/micro...
This project was brilliantly led by Sabrina Arif, and is a close collaboration with @fluca2406.bsky.social's lab, and the Global Microbiome Conservancy (Mathieu Groussin and Mathilde Poyet)
November 5, 2025 at 2:04 AM
This project was brilliantly led by Sabrina Arif, and is a close collaboration with @fluca2406.bsky.social's lab, and the Global Microbiome Conservancy (Mathieu Groussin and Mathilde Poyet)
3. Specific microbes like Bifidobacterium adolescentis (influenced by dairy intake) directly affected metabolic gene expression.
November 5, 2025 at 2:04 AM
3. Specific microbes like Bifidobacterium adolescentis (influenced by dairy intake) directly affected metabolic gene expression.
2. High-diversity microbiomes elicited a stronger host transcriptional response, while low-diversity microbiomes triggered epithelial restructuring & glycolysis – a stress response that characterizes several chronic inflammatory diseases.
November 5, 2025 at 2:04 AM
2. High-diversity microbiomes elicited a stronger host transcriptional response, while low-diversity microbiomes triggered epithelial restructuring & glycolysis – a stress response that characterizes several chronic inflammatory diseases.
1. Urban microbiomes triggered stronger host immune responses, including TNF signaling and bacterial antigen recognition.
November 5, 2025 at 2:04 AM
1. Urban microbiomes triggered stronger host immune responses, including TNF signaling and bacterial antigen recognition.
We used a cell culture-based experimental system, treating colonic epithelial cells with live gut microbiomes from rural and urban individuals from different populations (Ghana, Nigeria, Rwanda, Malaysia, US). We found super interesting results👇
November 5, 2025 at 2:04 AM
We used a cell culture-based experimental system, treating colonic epithelial cells with live gut microbiomes from rural and urban individuals from different populations (Ghana, Nigeria, Rwanda, Malaysia, US). We found super interesting results👇