bioRxiv Biochemistry
@biorxiv-biochem.bsky.social
A composition-matching algorithm, MatchIDR, identifies prion-like domains that localize to stress granules https://www.biorxiv.org/content/10.1101/2025.11.24.690216v1
November 28, 2025 at 3:45 AM
A composition-matching algorithm, MatchIDR, identifies prion-like domains that localize to stress granules https://www.biorxiv.org/content/10.1101/2025.11.24.690216v1
Topological adaptation of heliorhodopsins enables exogenous second-antenna acquisition in monoderm phototrophs https://www.biorxiv.org/content/10.1101/2025.11.27.691015v1
November 28, 2025 at 2:45 AM
Topological adaptation of heliorhodopsins enables exogenous second-antenna acquisition in monoderm phototrophs https://www.biorxiv.org/content/10.1101/2025.11.27.691015v1
Effects of cell growth and temperature on mitochondrial physiology of Drosophila melanogaster embryonic cell line https://www.biorxiv.org/content/10.1101/2025.11.25.690158v1
November 28, 2025 at 2:45 AM
Effects of cell growth and temperature on mitochondrial physiology of Drosophila melanogaster embryonic cell line https://www.biorxiv.org/content/10.1101/2025.11.25.690158v1
Multi-stem-loop constrained library enables accelerated SELEX for aptamers with superior kinetics and affinity https://www.biorxiv.org/content/10.1101/2025.11.27.690911v1
November 28, 2025 at 2:45 AM
Multi-stem-loop constrained library enables accelerated SELEX for aptamers with superior kinetics and affinity https://www.biorxiv.org/content/10.1101/2025.11.27.690911v1
Synthesis of stable isotope labeled analogs of phytanic acid for separate and combined tracing of alpha-, beta- and omega-oxidation https://www.biorxiv.org/content/10.1101/2025.11.24.689497v1
November 27, 2025 at 11:45 PM
Synthesis of stable isotope labeled analogs of phytanic acid for separate and combined tracing of alpha-, beta- and omega-oxidation https://www.biorxiv.org/content/10.1101/2025.11.24.689497v1
Experience from an HTS campaign: Investigation of susceptibility and rescue of SARS-CoV-2 nsp3 protease assay from metal contamination https://www.biorxiv.org/content/10.1101/2025.11.27.690678v1
November 27, 2025 at 10:45 PM
Experience from an HTS campaign: Investigation of susceptibility and rescue of SARS-CoV-2 nsp3 protease assay from metal contamination https://www.biorxiv.org/content/10.1101/2025.11.27.690678v1
TDP-43 controls RNA structure through high affinity lattice interactions https://www.biorxiv.org/content/10.1101/2025.11.26.690829v1
November 27, 2025 at 3:46 AM
TDP-43 controls RNA structure through high affinity lattice interactions https://www.biorxiv.org/content/10.1101/2025.11.26.690829v1
Structural basis for ATP regulation of human 5-lipoxygenase https://www.biorxiv.org/content/10.1101/2025.11.26.690380v1
November 27, 2025 at 3:45 AM
Structural basis for ATP regulation of human 5-lipoxygenase https://www.biorxiv.org/content/10.1101/2025.11.26.690380v1
GPR17 structure and agonism with small molecules and oxysterols https://www.biorxiv.org/content/10.1101/2025.11.26.690757v1
November 27, 2025 at 3:45 AM
GPR17 structure and agonism with small molecules and oxysterols https://www.biorxiv.org/content/10.1101/2025.11.26.690757v1
Structural insights into autophosphorylation-mediated heat shock response by the protein-arginine kinase McsAB https://www.biorxiv.org/content/10.1101/2025.11.26.690658v1
November 27, 2025 at 2:46 AM
Structural insights into autophosphorylation-mediated heat shock response by the protein-arginine kinase McsAB https://www.biorxiv.org/content/10.1101/2025.11.26.690658v1
Structural atlas of Pakpunavirus P7-1 reveals determinants of virion stability and genome ejection https://www.biorxiv.org/content/10.1101/2025.11.26.690771v1
November 27, 2025 at 2:46 AM
Structural atlas of Pakpunavirus P7-1 reveals determinants of virion stability and genome ejection https://www.biorxiv.org/content/10.1101/2025.11.26.690771v1
NanoBRET Tracer Development for Class I Bromodomain Target Engagement in Live Cells https://www.biorxiv.org/content/10.1101/2025.11.25.689777v1
November 26, 2025 at 9:45 PM
NanoBRET Tracer Development for Class I Bromodomain Target Engagement in Live Cells https://www.biorxiv.org/content/10.1101/2025.11.25.689777v1
A flexible Janus head: molecular determinants of a viral protein's RNAi suppressor and capsid forming activities https://www.biorxiv.org/content/10.1101/2025.11.26.690650v1
November 26, 2025 at 9:45 PM
A flexible Janus head: molecular determinants of a viral protein's RNAi suppressor and capsid forming activities https://www.biorxiv.org/content/10.1101/2025.11.26.690650v1
Mapping galectin-3 ligands in tear fluid establishes spliceoform-dependent lacritin binding https://www.biorxiv.org/content/10.1101/2025.11.24.690288v1
November 26, 2025 at 5:45 PM
Mapping galectin-3 ligands in tear fluid establishes spliceoform-dependent lacritin binding https://www.biorxiv.org/content/10.1101/2025.11.24.690288v1
Glucocorticoid-induced proteome and phosphoproteome changes in breast cancer cell lines https://www.biorxiv.org/content/10.1101/2025.11.25.690354v1
November 26, 2025 at 4:45 PM
Glucocorticoid-induced proteome and phosphoproteome changes in breast cancer cell lines https://www.biorxiv.org/content/10.1101/2025.11.25.690354v1
Structure-function studies on the serine protease domain of Factor VII activating protease (FSAP). https://www.biorxiv.org/content/10.1101/2025.11.25.690424v1
November 26, 2025 at 4:45 PM
Structure-function studies on the serine protease domain of Factor VII activating protease (FSAP). https://www.biorxiv.org/content/10.1101/2025.11.25.690424v1
Mitochondrial Respiratory Chain Function is crucial for Muscle Toxicity in Facioscapulohumeral Muscular Dystrophy https://www.biorxiv.org/content/10.1101/2025.11.25.690559v1
November 26, 2025 at 3:46 PM
Mitochondrial Respiratory Chain Function is crucial for Muscle Toxicity in Facioscapulohumeral Muscular Dystrophy https://www.biorxiv.org/content/10.1101/2025.11.25.690559v1
G-Quadruplex and i-Motif Structures in the SHMT1 5UTR Modulate Gene Expression https://www.biorxiv.org/content/10.1101/2025.11.24.690261v1
November 26, 2025 at 3:45 PM
G-Quadruplex and i-Motif Structures in the SHMT1 5UTR Modulate Gene Expression https://www.biorxiv.org/content/10.1101/2025.11.24.690261v1
Charge segregation in the C-terminal linker of FtsZ enables Z-ring scaling with prokaryotic cell width https://www.biorxiv.org/content/10.1101/2025.11.25.690400v1
November 26, 2025 at 3:45 PM
Charge segregation in the C-terminal linker of FtsZ enables Z-ring scaling with prokaryotic cell width https://www.biorxiv.org/content/10.1101/2025.11.25.690400v1
Conserved early steps of stemmadenine biosynthesis https://www.biorxiv.org/content/10.1101/2025.11.23.690000v1
November 26, 2025 at 2:45 PM
Conserved early steps of stemmadenine biosynthesis https://www.biorxiv.org/content/10.1101/2025.11.23.690000v1
Mapping Protein Occupancy on DNA with an Unnatural Cytosine Modification in Bio-orthogonal Contexts https://www.biorxiv.org/content/10.1101/2025.11.24.690163v1
November 26, 2025 at 3:45 AM
Mapping Protein Occupancy on DNA with an Unnatural Cytosine Modification in Bio-orthogonal Contexts https://www.biorxiv.org/content/10.1101/2025.11.24.690163v1
AlphaFlex: Ensembles of the human proteome representing disordered regions https://www.biorxiv.org/content/10.1101/2025.11.24.690279v1
November 26, 2025 at 2:45 AM
AlphaFlex: Ensembles of the human proteome representing disordered regions https://www.biorxiv.org/content/10.1101/2025.11.24.690279v1
A Charge-reversal Point Mutation Completely Depletes Flavin Chromophore from European Robin Cryptochrome 4a Protein https://www.biorxiv.org/content/10.1101/2025.11.24.690116v1
November 26, 2025 at 2:45 AM
A Charge-reversal Point Mutation Completely Depletes Flavin Chromophore from European Robin Cryptochrome 4a Protein https://www.biorxiv.org/content/10.1101/2025.11.24.690116v1
Anion supercharging enables structural assignment of oxidatively released O-glycans https://www.biorxiv.org/content/10.1101/2025.11.23.689986v1
November 26, 2025 at 2:45 AM
Anion supercharging enables structural assignment of oxidatively released O-glycans https://www.biorxiv.org/content/10.1101/2025.11.23.689986v1
Structural basis of stereochemical promiscuity by an umami taste receptor ortholog, Tas1r1/Tas1r3 from pufferfish https://www.biorxiv.org/content/10.1101/2025.11.24.689453v1
November 26, 2025 at 1:45 AM
Structural basis of stereochemical promiscuity by an umami taste receptor ortholog, Tas1r1/Tas1r3 from pufferfish https://www.biorxiv.org/content/10.1101/2025.11.24.689453v1