Bin Yu
biointelligenet.bsky.social
Bin Yu
@biointelligenet.bsky.social
Ph.D. student in Komiyama lab at UCSD, study olfactory learning, neurogenesis, and neuromodulation, U-DUB (UW) alumni
I am excited to share that the main part of my PhD thesis is now published in @science.org! I am grateful for my amazing mentor’s @takakikomiyama.bsky.social guidance and the contributions of all co-authors!
Our new paper is out in Science.

We identified a subgroup of cholinergic neurons that mediate sensory modality-specific attention. They change their funcitonal properties within secs of behavioral context change.

Congrats to Bin for the great thesis, and the team!

www.science.org/doi/10.1126/...
Cholinergic feedback for modality- and context-specific modulation of sensory representations
The brain’s ability to prioritize sensory information is crucial for adaptive behavior, yet its mechanisms remain unclear. We investigated basal forebrain cholinergic neurons modulating olfactory bulb...
www.science.org
June 20, 2025 at 4:41 PM
Reposted by Bin Yu
Our new paper is out in Science.

What is the synaptic plasticity rule in the brain, we asked. It turns out there are multiple, even within individual neurons.

Congrats Jake!

www.science.org/doi/10.1126/...
Distinct synaptic plasticity rules operate across dendritic compartments in vivo during learning
Synaptic plasticity underlies learning by modifying specific synaptic inputs to reshape neural activity and behavior. However, the rules governing which synapses will undergo different forms of plasti...
www.science.org
April 17, 2025 at 11:46 PM
Reposted by Bin Yu
663 days since the senseless tragedy that took An, we present a manuscript that reports some of the discoveries that she left us.

www.biorxiv.org/content/10.1...
Targeted stimulation of motor cortex neural ensembles drives learned movements
During the execution of learned motor skills, the neural population in the layer 2/3 (L2/3) of the primary motor cortex (M1) expresses a reproducible spatiotemporal activity pattern. It is debated whe...
www.biorxiv.org
January 7, 2025 at 5:53 AM