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naturepoker
@binomicalabs.org
Binomica Labs independent researcher by day, warehouse worker by night

Small thoughtful science

#phylogenetics #archaea #evolution #bioinformatics

@[email protected]
http://naturepoker.wordpress.com
https://orcid.org/0000-0002-6977-5440
This. Granted I might take deep, deep discount on more nvme drives.
November 23, 2025 at 5:56 PM
On a different note, here's another street side used books stall pickup. $2 for the two books! Looking forward to going through them.
November 21, 2025 at 4:19 PM
More images from the new Haloarchaea that needs a taxonomic assignment & name. Learning how to automate nd2 microscopy images analysis had been interesting.

Also managed to hunt down its closest relative, it looks similar except 2x larger. Significantly different genomes though.

🦠🧫🧪
November 21, 2025 at 12:40 PM
Cool crisp #nyc dawn this morning
November 17, 2025 at 12:21 PM
I'm pretty sure emoji type symbols go back to the very beginning of printing technologies if we know where to look.

Here's a fun early example, from 1909 Strand magazine
November 15, 2025 at 10:22 PM
Please tell me this is just a wild guess. Democrats decided to cave in because successfully defending ACA coverage will get rid of a talking point in the midterms?

newrepublic.com/post/202948/...
November 10, 2025 at 9:37 PM
Picked up a #Polaroid Sun660 from a curve sale for pocket change. Very happy to see it's working properly with fresh film!

Doubly glad to capture the last of the autumn leaves - I was afraid I wouldn't be able to take them before the rains washed them away.

#analogphotography
November 8, 2025 at 9:58 PM
Ok I think I'm set for the winter.
November 7, 2025 at 10:50 PM
Check this out - first image of a new Halococcus species I discovered with collaborators. Still figuring out the scheme to name the darn thing.

Independent research & amateur biology FTW.

🧫🦠🧪
November 6, 2025 at 4:52 PM
Going through @samuelhorsfield.bsky.social presentation on pangenome graphs in comparative genomics, courtesy of @training.ebi.embl.org.

Fascinating tidbit on history of alignment based sequence graph - it goes all the way back to 1989 (Hein), era of Apple IIs and IBM PS/2s. Great talk!

💻🧬🦠🧫
November 5, 2025 at 3:19 PM
#nyc marathon day. Ran straight into this crowd coming back from work!
November 2, 2025 at 3:59 PM
오랜만에 눈마새를 정독중에 이 부분을 다시 읽었다.

자기완성을 위한 인생을 조심하라. 나중에 라수가 독자를 위해 풀이해 줄때 까지 정말 알쏭달쏭한 문장이었는데.

젠장. 한국밖의 사람들이 이 소설을 읽지 못하고 살아가야 한다는 사실은 굉장한 불의가 아닐 수 없다.

그럼, 내가 모르는 언어와 문화들의 시와 이야기들도 이처럼 재미있고 인생들을 흔들어 놓는 존재들 이라는 것이겠지.

인생이 어둡고 갑갑해질때 이런 생각을 하면 좀 가슴이 시원해지는 느낌이 든다.
October 26, 2025 at 12:09 AM
This makes surprising amount of sense.
October 25, 2025 at 2:22 AM
Another fun #archaeasky paper to ponder about. HGT driven copy number expansion led to structural diversification, collection of which ended up being the eukaryotic replisome - seems to be the gist, as demonstrated by the author's very handy illustration.

🦠🧫
October 21, 2025 at 6:58 PM
Ah @theonion.com , never change.
October 21, 2025 at 1:14 AM
Depravity pervading through our generation in one image.

Found during random browsing.
October 21, 2025 at 1:05 AM
This sits at the highest place in my lab lol
October 17, 2025 at 1:17 PM
This particular figure was quite striking - physical microscopy of the E. coli genome. Somehow we run these tangles mess through pores (often not breaking them over significant distances) and render them into reliable representation of whole genomic compartments.

🧫🦠
October 15, 2025 at 2:25 PM
There's another artists collective building right across the street from our lab with fascinating murals wrapping around the walls. Alas, the owners got rid of the whole thing yesterday - it's just a gray block now 😞

These photos turned out to be the paintings in their final few days

#nyc
October 6, 2025 at 12:09 AM
Taking a breather from a long exhausting day. Reminds me I need to go back to the lab and build some heatmaps.
October 2, 2025 at 10:58 PM
Man this one's a trip down the memory lane. One of more surreal experiences in my life was sorting through mislabeled mummies in the old Cairo museum of antiquities, surrounded by burning smoke of their ministry of information building - right after the Tahrir square incident.
September 25, 2025 at 8:40 PM
Catching the morning moon on the way back from work. Wow, it almost feels like there's a spotlight in the sky. #nyc
September 8, 2025 at 9:35 AM
Your last saved picture is your moral philosophy

I'm confused.
September 7, 2025 at 4:07 PM
I think I finally untangled this darn Archaeal genome. About three full days of work building some middleware. Good grief, I had an easier time assembling rabbit neuron rna-seq reads and running PCA on it. Before and after graph for the Archaea, final product's fully circularized.
September 5, 2025 at 7:19 PM
August 26, 2025 at 2:55 AM