Please reach out if you are curious, dedicated, motivated, and interested ✨

www.findaphd.com/phds/project...

😂😂🫶🏼

Thanks Caroline!

Thanks Ciarán!

¡Gracias Carmen!

Finally, we didn’t give a name to the method… any suggestions? 🤔

I’m also very thankful to the reviewers for the time they put into it and their constructive comments that made the paper more robust and exciting.

I feel very proud of how my team has worked together to make this happen and very thankful to our collaborators and funders without which it wouldn’t have happened.

All the data can be found with the article and we also put it in this fantastic website thanks to Amonida Zadissa 🇵🇸’s team and UK Dementia Research Institute.

neuromics-explorer.ukdri.ac.uk/diaz-castro

These communication pathways are modulated by peripheral inflammation, e.g. WNT10B-FZD7. 80% of the ligand-receptors pairs we identified in mouse are also present in human brain vasculature-astrocyte and the expression of some of them is altered in Alzheimer’s disease and Multiple Sclerosis.

We developed a new method to identify the proteins that are located in the astrocyte branches (endfeet) that enwrap the mouse brain blood vessels. Among the proteins identified there are many receptors for ligands produced by the brain endothelial cells (vasculature).