Bartomeu Colom
@bartomeucolom.bsky.social
Senior Scientist @altoslabs, previously @sangerinstitute.bsky.social. Stem cells, somatic mutations & cell competition in aging and early cancer. Views are my own.
https://scholar.google.com/citations?hl=en&user=o5vRhIAAAAAJ
https://scholar.google.com/citations?hl=en&user=o5vRhIAAAAAJ
'Mechanisms of cellular fitness and cell competition: Towards an integrated view'
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October 15, 2025 at 10:11 AM
'Mechanisms of cellular fitness and cell competition: Towards an integrated view'
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
'Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 12, 2025 at 10:33 AM
'Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'The Somatic Mosaicism across Human Tissues Network'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 10, 2025 at 10:19 AM
'The Somatic Mosaicism across Human Tissues Network'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Cross-tissue multicellular coordination and its rewiring in cancer'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 10, 2025 at 8:16 AM
'Cross-tissue multicellular coordination and its rewiring in cancer'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
"Cell cycle duration determines oncogenic transformation capacity"
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www.nature.com/articles/s41...
May 29, 2025 at 10:20 AM
"Cell cycle duration determines oncogenic transformation capacity"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Neural cell competition sculpting brain from cradle to grave'
academic.oup.com/nsr/article/...
academic.oup.com/nsr/article/...
May 6, 2025 at 7:45 AM
'Neural cell competition sculpting brain from cradle to grave'
academic.oup.com/nsr/article/...
academic.oup.com/nsr/article/...
'Geographic and age variations in mutational processes in colorectal cancer'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
April 24, 2025 at 8:24 AM
'Geographic and age variations in mutational processes in colorectal cancer'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Emergence and properties of adult mammalian epidermal stem cells'
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March 27, 2025 at 8:42 AM
'Emergence and properties of adult mammalian epidermal stem cells'
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'Clonal driver neoantigen loss under EGFR TKI and immune selection pressures'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 26, 2025 at 4:11 PM
'Clonal driver neoantigen loss under EGFR TKI and immune selection pressures'
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www.nature.com/articles/s41...
'Translating premalignant biology to accelerate non-small-cell lung cancer interception'
www.nature.com/articles/s41...
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March 24, 2025 at 3:39 PM
'Translating premalignant biology to accelerate non-small-cell lung cancer interception'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'The end of the genetic paradigm of cancer'
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March 21, 2025 at 1:26 PM
'The end of the genetic paradigm of cancer'
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
'Cancer evolution: from Darwin to the Extended Evolutionary Synthesis'
www.cell.com/trends/cance...
www.cell.com/trends/cance...
March 11, 2025 at 4:11 PM
'Cancer evolution: from Darwin to the Extended Evolutionary Synthesis'
www.cell.com/trends/cance...
www.cell.com/trends/cance...
'Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis'
www.cell.com/cancer-cell/...
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March 11, 2025 at 9:06 AM
'Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis'
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
'Clonal dynamics and somatic evolution of haematopoiesis in mouse'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 6, 2025 at 9:31 AM
'Clonal dynamics and somatic evolution of haematopoiesis in mouse'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Exposomal determinants of non-geneticplasticity in tumor initiation'
www.cell.com/trends/cance...
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March 3, 2025 at 10:26 AM
'Exposomal determinants of non-geneticplasticity in tumor initiation'
www.cell.com/trends/cance...
www.cell.com/trends/cance...
'Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation'
www.sciencedirect.com/science/arti...
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February 28, 2025 at 9:03 AM
'Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation'
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'Spatiotemporal single-cell roadmap of human skin wound healing'
www.cell.com/cell-stem-ce...
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January 7, 2025 at 10:31 AM
'Spatiotemporal single-cell roadmap of human skin wound healing'
www.cell.com/cell-stem-ce...
www.cell.com/cell-stem-ce...
'Spatial transcriptomic clocks reveal cell proximity effects in brain ageing'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 19, 2024 at 10:51 AM
'Spatial transcriptomic clocks reveal cell proximity effects in brain ageing'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 13, 2024 at 3:39 PM
'iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cells'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'An injury-induced mesenchymal-epithelial cell niche coordinates regenerative responses in the lung'
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December 13, 2024 at 9:11 AM
'An injury-induced mesenchymal-epithelial cell niche coordinates regenerative responses in the lung'
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www.science.org/doi/10.1126/...
'Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 12, 2024 at 8:56 AM
'Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Imperfect wound healing sets the stage for chronic diseases'
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December 9, 2024 at 9:00 AM
'Imperfect wound healing sets the stage for chronic diseases'
www.science.org/doi/10.1126/...
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'The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 5, 2024 at 1:30 PM
'The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 5, 2024 at 11:24 AM
'Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
'Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 29, 2024 at 5:54 PM
'Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER'
www.nature.com/articles/s41...
www.nature.com/articles/s41...