Alexandre Dumoulin
@axonsalex.bsky.social
Developmental Neurobiologist at UZH | Microscopy Enthusiast. Using the chicken embryo to decipher the molecular mechanisms of neural circuit formation. Fascinated by axonal growth cones, primary cilia, and extracellular vesicles.
very nice interview Joaquín!
August 5, 2025 at 12:37 PM
very nice interview Joaquín!
Thanks Luc! and yes it is! 😉
July 16, 2025 at 7:11 AM
Thanks Luc! and yes it is! 😉
Here’s an embryonic axonal growth cone labeled with PK Mem dye (red) and tubulin (blue), imaged every 2 seconds. 🤩
July 16, 2025 at 6:46 AM
Here’s an embryonic axonal growth cone labeled with PK Mem dye (red) and tubulin (blue), imaged every 2 seconds. 🤩
cool!
here are chick commissural axons crossing the neural tube floor plate :): bsky.app/profile/axon...
here are chick commissural axons crossing the neural tube floor plate :): bsky.app/profile/axon...
May 2, 2025 at 8:11 AM
cool!
here are chick commissural axons crossing the neural tube floor plate :): bsky.app/profile/axon...
here are chick commissural axons crossing the neural tube floor plate :): bsky.app/profile/axon...
Hi Erica,
thanks!
for 2D cultures: journals.biologists.com/jcs/article/...
for 3D cultures: www.frontiersin.org/journals/mol...
for live imaging I used 8-well IBIDI μ-slides with same PLL/Laminin coating and the same medium as in the JCS paper.
Cheers
Alex
thanks!
for 2D cultures: journals.biologists.com/jcs/article/...
for 3D cultures: www.frontiersin.org/journals/mol...
for live imaging I used 8-well IBIDI μ-slides with same PLL/Laminin coating and the same medium as in the JCS paper.
Cheers
Alex
The SynCAM synaptic cell adhesion molecules are involved in sensory axon pathfinding by regulating axon–axon contacts
ABSTRACT. Synaptic cell adhesion molecules (SynCAMs) are crucial for synapse formation and plasticity. However, we have previously demonstrated that SynCAMs are also required during earlier stages of ...
journals.biologists.com
May 2, 2025 at 8:09 AM
Hi Erica,
thanks!
for 2D cultures: journals.biologists.com/jcs/article/...
for 3D cultures: www.frontiersin.org/journals/mol...
for live imaging I used 8-well IBIDI μ-slides with same PLL/Laminin coating and the same medium as in the JCS paper.
Cheers
Alex
thanks!
for 2D cultures: journals.biologists.com/jcs/article/...
for 3D cultures: www.frontiersin.org/journals/mol...
for live imaging I used 8-well IBIDI μ-slides with same PLL/Laminin coating and the same medium as in the JCS paper.
Cheers
Alex
Reposted by Alexandre Dumoulin
These ones are growing in a dish, but in a developing embryo or brain, each growth cone would be sniffing its way through a complex molecular terrain, often over long distances to find its correct synaptic partners.
April 30, 2025 at 11:09 AM
These ones are growing in a dish, but in a developing embryo or brain, each growth cone would be sniffing its way through a complex molecular terrain, often over long distances to find its correct synaptic partners.
Hi Luc, thanks!
it is indeed Spy555-FastAct.
Cheers
it is indeed Spy555-FastAct.
Cheers
April 30, 2025 at 10:15 AM
Hi Luc, thanks!
it is indeed Spy555-FastAct.
Cheers
it is indeed Spy555-FastAct.
Cheers
me too! They seem to be retraction fibers that are then fragmenting into these small vesicles. It has been described in some migrating cells/cancer cells before. We are now inestigating it in the context of axon growth and guidance!
January 10, 2025 at 1:53 PM
me too! They seem to be retraction fibers that are then fragmenting into these small vesicles. It has been described in some migrating cells/cancer cells before. We are now inestigating it in the context of axon growth and guidance!
Yes, it is, I wrote it in the ALT text but somehow it I can't see it. SPY555-FastAct
January 10, 2025 at 1:11 PM
Yes, it is, I wrote it in the ALT text but somehow it I can't see it. SPY555-FastAct
And sometimes accross the floor plate 🙂
January 10, 2025 at 1:07 PM
And sometimes accross the floor plate 🙂