Arnone Lab
@arnonelab.bsky.social
Group established in 2000, studying Echinoderms to unravel the evolution of organs and body parts by comparison of gene regulatory networks. https://arnonelab.it/
Pinned
Single-nucleus profiling highlights the all-brain echinoderm nervous system
A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
www.science.org
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Arnone Lab
In preprints: cell type-specific gene regulation through the lens of echinoderms
Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues
doi.org/10.1242/dev....
Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues
doi.org/10.1242/dev....
November 18, 2025 at 3:06 PM
In preprints: cell type-specific gene regulation through the lens of echinoderms
Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues
doi.org/10.1242/dev....
Periklis Paganos and @arnonelab.bsky.social discuss a recent #preprint by Jonas Maurice Brandenburg, David Aaron Garfield and colleagues
doi.org/10.1242/dev....
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Single-nucleus profiling highlights the all-brain echinoderm nervous system
A sea urchin is a head with a brain-like organization and a vertebrate-type retinal signature.
www.science.org
November 5, 2025 at 7:03 PM
Our study, just published in #ScienceAdvances and funded by @hfspo.bsky.social, explores the post metamorphic cell composition of the sea urchin juvenile, revealing that its body is head-like. Long considered brainless creatures, they’re all brain instead!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Arnone Lab
We discuss new research on sea urchins, how echinoderms remain relevant experimental systems in the multiomics era, and the future of the cell type evolution and development field.
November 3, 2025 at 3:02 PM
We discuss new research on sea urchins, how echinoderms remain relevant experimental systems in the multiomics era, and the future of the cell type evolution and development field.
Reposted by Arnone Lab
Thrilled to share my newest perspective article with @arnonelab.bsky.social in @dev-journal.bsky.social
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
In preprints: cell type-specific gene regulation through the lens of echinoderms
One of the most intriguing questions in developmental biology is how a single cell, the zygote, gives rise to hundreds or millions of distinct cell types during embryogenesis. Decades of research have...
journals.biologists.com
November 3, 2025 at 3:02 PM
Thrilled to share my newest perspective article with @arnonelab.bsky.social in @dev-journal.bsky.social
journals.biologists.com/dev/article/...
journals.biologists.com/dev/article/...
We‘re thrilled to be involved in this great open science initiative; @mlrusciano.bsky.social really enjoyed testing this tool in sea urchins!
How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵
Check our latest preprint
Check our latest preprint
A toolkit for testing membrane-localising tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
www.biorxiv.org
October 23, 2025 at 8:40 AM
We‘re thrilled to be involved in this great open science initiative; @mlrusciano.bsky.social really enjoyed testing this tool in sea urchins!
Very proud to be a part of this!
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 24, 2025 at 4:05 PM
Very proud to be a part of this!
Reposted by Arnone Lab
Do you want to unravel the function of fluorescent cells in marine organisms?
Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers!
To apply: www.szn.it/.../ph-d-pro...
Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers!
To apply: www.szn.it/.../ph-d-pro...
May 23, 2025 at 4:36 PM
Do you want to unravel the function of fluorescent cells in marine organisms?
Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers!
To apply: www.szn.it/.../ph-d-pro...
Join the Annunziata lab @szn.it for a PhD project exploring embryonic origins, function and biotechnological potential of fluorescent cell type in sea cucumbers!
To apply: www.szn.it/.../ph-d-pro...
Do you want to understand how developmental programs are encoded in animal genomes? Join our lab at the @szndohrn.bsky.social for a PhD project to unravel the developmental dynamics in sea urchins during the metamorphosis from larva to juvenile.
Deadline JUNE 14th!
www.szn.it/index.php/it...
Deadline JUNE 14th!
www.szn.it/index.php/it...
May 21, 2025 at 2:31 PM
Do you want to understand how developmental programs are encoded in animal genomes? Join our lab at the @szndohrn.bsky.social for a PhD project to unravel the developmental dynamics in sea urchins during the metamorphosis from larva to juvenile.
Deadline JUNE 14th!
www.szn.it/index.php/it...
Deadline JUNE 14th!
www.szn.it/index.php/it...
Reposted by Arnone Lab
It's only mid-April, but course season at the MBL is already underway! 🔬
Gene Regulatory Networks for Development started on April 6 and wraps up later this week 🧬 Congrats to this year's cohort! 👏
📲 Read more about the GRN course: bit.ly/3Wi6LQE
Gene Regulatory Networks for Development started on April 6 and wraps up later this week 🧬 Congrats to this year's cohort! 👏
📲 Read more about the GRN course: bit.ly/3Wi6LQE
April 16, 2025 at 10:30 PM
It's only mid-April, but course season at the MBL is already underway! 🔬
Gene Regulatory Networks for Development started on April 6 and wraps up later this week 🧬 Congrats to this year's cohort! 👏
📲 Read more about the GRN course: bit.ly/3Wi6LQE
Gene Regulatory Networks for Development started on April 6 and wraps up later this week 🧬 Congrats to this year's cohort! 👏
📲 Read more about the GRN course: bit.ly/3Wi6LQE
Reposted by Arnone Lab
Another terrific Developmental Biology of the Sea Urchin & Other Marine Invertebrates is done! Thank you to all attendees for sharing your awesome science, the co-organizers for their hard work, our sponsors, and @mblscience.bsky.social for being such a great venue. Photo credit to Bob Morris 👏
April 8, 2025 at 6:42 PM
Another terrific Developmental Biology of the Sea Urchin & Other Marine Invertebrates is done! Thank you to all attendees for sharing your awesome science, the co-organizers for their hard work, our sponsors, and @mblscience.bsky.social for being such a great venue. Photo credit to Bob Morris 👏
Reposted by Arnone Lab
Also a blast from the past! Another preprint is now available from my first postdoc in the @arnonelab.bsky.social at @szndohrn.bsky.social www.biorxiv.org/content/10.1...
March 28, 2025 at 9:36 PM
Also a blast from the past! Another preprint is now available from my first postdoc in the @arnonelab.bsky.social at @szndohrn.bsky.social www.biorxiv.org/content/10.1...
Reposted by Arnone Lab
Excited to share our latest work!
@arnonelab.bsky.social
, @John Kirwan, @Ina Arnone. We investigated the impact of light on the phenotypic response to food in sea urchin larvae.
Check it out here: www.frontiersin.org/journals/eco....
@szndohrn.bsky.social, #SZN, #seaurchin, #ecoevodevo
@arnonelab.bsky.social
, @John Kirwan, @Ina Arnone. We investigated the impact of light on the phenotypic response to food in sea urchin larvae.
Check it out here: www.frontiersin.org/journals/eco....
@szndohrn.bsky.social, #SZN, #seaurchin, #ecoevodevo
Frontiers | Phenotypic response to food availability in sea urchin larvae and impact of light during development and growth
www.frontiersin.org
March 20, 2025 at 1:03 PM
Excited to share our latest work!
@arnonelab.bsky.social
, @John Kirwan, @Ina Arnone. We investigated the impact of light on the phenotypic response to food in sea urchin larvae.
Check it out here: www.frontiersin.org/journals/eco....
@szndohrn.bsky.social, #SZN, #seaurchin, #ecoevodevo
@arnonelab.bsky.social
, @John Kirwan, @Ina Arnone. We investigated the impact of light on the phenotypic response to food in sea urchin larvae.
Check it out here: www.frontiersin.org/journals/eco....
@szndohrn.bsky.social, #SZN, #seaurchin, #ecoevodevo
Happy to share this:
Ricercatori della Stazione Dohrn pubblicano su Nature nuovo studio sul plancton.
Il lavoro firmato da Angela Falciatore, Chris Bowler e Maurizio Ribera d’Alcalà.
Avevano cominciato a lavorare insieme 30 anni fa a Napoli...
napoli.repubblica.it/cronaca/2024...
Ricercatori della Stazione Dohrn pubblicano su Nature nuovo studio sul plancton.
Il lavoro firmato da Angela Falciatore, Chris Bowler e Maurizio Ribera d’Alcalà.
Avevano cominciato a lavorare insieme 30 anni fa a Napoli...
napoli.repubblica.it/cronaca/2024...
December 27, 2024 at 6:41 PM
Happy to share this:
Ricercatori della Stazione Dohrn pubblicano su Nature nuovo studio sul plancton.
Il lavoro firmato da Angela Falciatore, Chris Bowler e Maurizio Ribera d’Alcalà.
Avevano cominciato a lavorare insieme 30 anni fa a Napoli...
napoli.repubblica.it/cronaca/2024...
Ricercatori della Stazione Dohrn pubblicano su Nature nuovo studio sul plancton.
Il lavoro firmato da Angela Falciatore, Chris Bowler e Maurizio Ribera d’Alcalà.
Avevano cominciato a lavorare insieme 30 anni fa a Napoli...
napoli.repubblica.it/cronaca/2024...
Amazing work from the group of my former colleague, for ever friend, Angela Falciatore and colleagues: the "pigment of imagination" rocks! Congratulations! 🎉🍾🥂
Excited to share this work from our lab @IBPC and collaborators! Thanks to diatoms, some of the mysteries surrounding phytochrome photoreceptors in the oceans are beginning to be unraveled! Phytochrome remains the "pigment of imagination’
Congratulations to all the authors!
doi.org/10.1038/s415...
Congratulations to all the authors!
doi.org/10.1038/s415...
December 18, 2024 at 5:58 PM
Amazing work from the group of my former colleague, for ever friend, Angela Falciatore and colleagues: the "pigment of imagination" rocks! Congratulations! 🎉🍾🥂
Reposted by Arnone Lab
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes https://www.biorxiv.org/content/10.1101/2024.11.30.626178v1
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes https://www.biorxiv.org/content/10.1101/2024.11.30.626178v1
Despite the growing abundance of sequenced animal genomes, we only have detailed knowledge of regula
www.biorxiv.org
December 1, 2024 at 8:32 AM
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes https://www.biorxiv.org/content/10.1101/2024.11.30.626178v1
Thrilled to share this new work resulting from a great collaboration of my lab with the labs of Ignacio Maeso and Veronica Hinman, started with the dear José Luis Gómez-Skarmeta many years ago. Take a look!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes
Despite the growing abundance of sequenced animal genomes, we only have detailed knowledge of regulatory organization for a handful of lineages, particularly flies and vertebrates. These two groups of...
www.biorxiv.org
December 1, 2024 at 11:24 AM
Thrilled to share this new work resulting from a great collaboration of my lab with the labs of Ignacio Maeso and Veronica Hinman, started with the dear José Luis Gómez-Skarmeta many years ago. Take a look!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Arnone Lab
Alright, I guess someone had to do this. Let me know if I forgot you (or anyone else), I can add accounts! go.bsky.app/DRMSeby
November 10, 2024 at 12:44 PM
Alright, I guess someone had to do this. Let me know if I forgot you (or anyone else), I can add accounts! go.bsky.app/DRMSeby
Reposted by Arnone Lab
Looking for a tag to localise fluorescent proteins to the plasma membrane? Unsure which tag might work in your species? We generated a toolkit of 11 membrane-localising tags, which can be screened rapidly by microinjecting mRNA in your species of interest. 1/4
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A toolkit for testing membrane localisation tags across species
Transgenic markers and tools have revolutionised how we study cells and developing organisms. Some of the elements needed to construct those tools are universally applicable (e.g. fluorescent proteins...
www.biorxiv.org
November 12, 2024 at 11:05 PM
Looking for a tag to localise fluorescent proteins to the plasma membrane? Unsure which tag might work in your species? We generated a toolkit of 11 membrane-localising tags, which can be screened rapidly by microinjecting mRNA in your species of interest. 1/4
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...