Arjun Bhattacharya
arjunbhattac.bsky.social
Arjun Bhattacharya
@arjunbhattac.bsky.social
Assistant Professor, Epidemiology at MD Anderson. Molecular epi and statistical genomics to understand cancer and human development

https://bhattacharya-lab.com/
We are getting so many of these recently. It’s so frustrating.
October 25, 2025 at 1:45 AM
It’s open-weighted though
October 22, 2025 at 5:41 PM
Sean and Yung-Han both were awarded travel awards for their presentations, underscoring the importance of their work and the hard work they've put in for these projects. Looking forward to #ashg25.
October 8, 2025 at 11:31 PM
Star PhD student @ytchang11.bsky.social will present an empirical Bayes method to formally test the replication composite null hypothesis in GWAS, effectively controlling FDR and maintaining strong power. Big downstream implications to check out in her pre-print: www.medrxiv.org/content/10.1....
Formal Statistical Replication Analysis in Lung Cancer Genome-Wide Association Studies
Dozens of genome-wide association studies (GWAS) have identified thousands of single nucleotide polymor-phisms (SNPs) associated with lung cancer risk. However, it remains challenging to translate the...
www.medrxiv.org
October 8, 2025 at 11:31 PM
@seantbres.bsky.social will talk about a placental long-read RNA-seq isoform reference + how using it with short reads improves transcript quantification and DTE/U analyses. Cool results in the preprint below. More maternal-fetal health work soon in GxE/POE analyses.

www.biorxiv.org/content/10.1...
Long-read transcriptome assembly reveals vast isoform diversity in the placenta associated with metabolic and endocrine function
The placenta plays a critical role in fetal development and mediates maternal metabolic effects on offspring health outcomes. Despite its importance, the placenta remains understudied in large-scale g...
www.biorxiv.org
October 8, 2025 at 11:31 PM
Taylor also was recently nominated internally and submitted an early K99/R00 award to NCI. She did a tremendous amount of work for a really exciting proposal!
October 8, 2025 at 11:31 PM
@taylorhead.bsky.social will talk about integrating long-read based transcript assemblies can improve QTL mapping and GWAS integration for breast cancer risk, building off her recent work showing eQTL colocalization and TWAS are HIGHLY sensitive to annotation choice.

www.biorxiv.org/content/10.1...
Quantification method affects replicability of eQTL analysis, colocalization, and TWAS
eQTL mapping and TWAS are widely used to contextualize GWAS, yet the impact of RNA-seq processing choices remains unexplored. We find that RNA-seq quantification method and transcriptomic reference su...
www.biorxiv.org
October 8, 2025 at 11:31 PM
On a personal note, I'm honored to be named an Emerging Leader by BJC! We're excited to continue our work in genomic mechanisms for cancer risk and progression to discover novel biomarkers for risk stratification and prognosis.

www.nature.com/collections/...
Emerging Leaders | Emerging Leaders - British Journal of Cancer
BJC’s Emerging Leaders collection recognises stand-out early-to-mid career researchers, clinicians, and educators within the field of oncology.
www.nature.com
August 20, 2025 at 9:09 PM
No espresso martinis for Lola?
December 26, 2024 at 12:57 AM
Thanks, Mike!
December 2, 2023 at 12:50 PM