Ali Özgür Argunsah
@argunsah.bsky.social
Reposted by Ali Özgür Argunsah
How does the brain build itself? 🧠📈
Join us on Dec. 9, 10-12pm PT for a webinar presenting the findings from 12 papers mapping brain development in new detail.
🔗 https://alleninstitute-org.zoom.us/webinar/register/WN_phxk87APQh-kgRYqp0jO5Q#/registration
Image: Jasiek Krzysztofiak/@nature.com
Join us on Dec. 9, 10-12pm PT for a webinar presenting the findings from 12 papers mapping brain development in new detail.
🔗 https://alleninstitute-org.zoom.us/webinar/register/WN_phxk87APQh-kgRYqp0jO5Q#/registration
Image: Jasiek Krzysztofiak/@nature.com
December 7, 2025 at 4:52 PM
How does the brain build itself? 🧠📈
Join us on Dec. 9, 10-12pm PT for a webinar presenting the findings from 12 papers mapping brain development in new detail.
🔗 https://alleninstitute-org.zoom.us/webinar/register/WN_phxk87APQh-kgRYqp0jO5Q#/registration
Image: Jasiek Krzysztofiak/@nature.com
Join us on Dec. 9, 10-12pm PT for a webinar presenting the findings from 12 papers mapping brain development in new detail.
🔗 https://alleninstitute-org.zoom.us/webinar/register/WN_phxk87APQh-kgRYqp0jO5Q#/registration
Image: Jasiek Krzysztofiak/@nature.com
Reposted by Ali Özgür Argunsah
Another nail in the coffin for PCA?
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification
Most behaviors involve neural dynamics in high-dimensional activity spaces. A common approach is to extract dimensions that capture task-related variability, such as those separating stimuli or choice...
www.biorxiv.org
November 23, 2025 at 3:16 PM
Another nail in the coffin for PCA?
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
- doesn’t linearize, distorting similarity metrics
- is biased by temporal jitter across epochs
- may miss important dimensions for transient amplification
If you think there is a state space, use a state space model!
Reposted by Ali Özgür Argunsah
Science Matters. 🔬
For 80 years, science has been a north star for the U.S. In 1945, Vannevar Bush’s report Science, The Endless Frontier called for bold government investment in research transforming our health, economy, quality of life. Science is not zero-sum—it creates value and better lives.
For 80 years, science has been a north star for the U.S. In 1945, Vannevar Bush’s report Science, The Endless Frontier called for bold government investment in research transforming our health, economy, quality of life. Science is not zero-sum—it creates value and better lives.
March 7, 2025 at 5:25 AM
Science Matters. 🔬
For 80 years, science has been a north star for the U.S. In 1945, Vannevar Bush’s report Science, The Endless Frontier called for bold government investment in research transforming our health, economy, quality of life. Science is not zero-sum—it creates value and better lives.
For 80 years, science has been a north star for the U.S. In 1945, Vannevar Bush’s report Science, The Endless Frontier called for bold government investment in research transforming our health, economy, quality of life. Science is not zero-sum—it creates value and better lives.
New collaboration: Compartmentalization and stabilization of inhibitory synapses in CA1 after fear conditioning. www.biorxiv.org/content/10.1...
Learning reorganizes dendritic and stabilizes axonal initial segment inhibitory synapses in CA1 pyramidal neurons
Structural synaptic plasticity underlies the changes in brain connectivity required for learning and memory. Inhibitory synapses (INS) target all subcellular domains of excitatory pyramidal neurons (P...
www.biorxiv.org
March 5, 2025 at 9:55 AM
New collaboration: Compartmentalization and stabilization of inhibitory synapses in CA1 after fear conditioning. www.biorxiv.org/content/10.1...