Taking advantage of the genomic diversity in UHGV, we used comparative genomics to examine in detail diversity-generating retroelements, methyltransferases, and endolysins, proposing mechanisms by which these functions enhance a phage’s capacity to infect new hosts. (7/8)

We then examined the genetic factors underlying broader host range and found that functions involved in phage-host interactions across multiple stages of the infection cycle shape a phage's ability to switch hosts. (6/8)

Using UHGV, we profiled thousands of human gut metagenomes and identified a subset of hyperprevalent phages found around the globe. Leveraging host prediction data, we found that these phages have markedly higher host ranges. (5/8)

Another key challenge in virome research is that most viruses lack taxonomic classification, leading to ad hoc approaches that hinder cross-study comparisons. To address this, we developed a taxonomy-like framework and a tool for assigning user's genomes to UHGV clusters. (4/8)

Viral proteins are difficult to annotate, making it hard to infer their biology from genomes. We developed a pipeline that integrates sequence- and structure-based methods to improve functional annotation and reveal novel protein domains. (3/8)

🚨New preprint out!
We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research. (1/8)
www.biorxiv.org/content/10.1...

Is there anything you can do to request a fix in Google Scholar? The title of a recent paper is rendered wrong there (apparently, this is from the XML they use to get the data). I also had some recent problems where they replaced a peer-reviewed paper by its preprint