The title seems higher than the paper.
They say “show individual nucleoporins” but Fig 1 is just public AlphaFold models.
Typical basket NUPs aren’t even identified.
“We present the AtNPC model” - you can’t model at 35Å.
They say “show individual nucleoporins” but Fig 1 is just public AlphaFold models.
Typical basket NUPs aren’t even identified.
“We present the AtNPC model” - you can’t model at 35Å.
November 5, 2025 at 10:43 PM
The title seems higher than the paper.
They say “show individual nucleoporins” but Fig 1 is just public AlphaFold models.
Typical basket NUPs aren’t even identified.
“We present the AtNPC model” - you can’t model at 35Å.
They say “show individual nucleoporins” but Fig 1 is just public AlphaFold models.
Typical basket NUPs aren’t even identified.
“We present the AtNPC model” - you can’t model at 35Å.
Slower focused search beats rushing. Taxi drivers who drive slower pick up more passengers. Attention > speed. Brilliant work!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
November 4, 2025 at 8:39 PM
Slower focused search beats rushing. Taxi drivers who drive slower pick up more passengers. Attention > speed. Brilliant work!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Science in the spotlight! Buildings in Shenzhen lit with research themes, and scientists Xue Qikun and Nieng Yan carrying the torch for the national games. So refreshing to see science celebrated. Congrats to both on the relay!
November 3, 2025 at 10:19 AM
Science in the spotlight! Buildings in Shenzhen lit with research themes, and scientists Xue Qikun and Nieng Yan carrying the torch for the national games. So refreshing to see science celebrated. Congrats to both on the relay!
What a gem from @dudinlab.bsky.social @gautamdey.bsky.social @centriolelab.bsky.social in Cell! Expansion microscopy atlas of >200 eukaryotes comparing cytoskeletal architectures revealing structures not seen before. Stunning visualisation! Exactly the kind of transformative cell biology we need.
October 31, 2025 at 5:45 PM
What a gem from @dudinlab.bsky.social @gautamdey.bsky.social @centriolelab.bsky.social in Cell! Expansion microscopy atlas of >200 eukaryotes comparing cytoskeletal architectures revealing structures not seen before. Stunning visualisation! Exactly the kind of transformative cell biology we need.
Sweden: celebrating structural biology & protein synthesis! Saluting Anders Liljas & Måns Ehrenberg for years of shaping discoveries and service to the Nobel committee. Friends and colleagues gathering to discuss transformative advances and how to push the boundaries next.
October 30, 2025 at 10:13 AM
Sweden: celebrating structural biology & protein synthesis! Saluting Anders Liljas & Måns Ehrenberg for years of shaping discoveries and service to the Nobel committee. Friends and colleagues gathering to discuss transformative advances and how to push the boundaries next.
Warm congratulations to the young scientists recipients of the 2025 Nordic Photosynthesis community prizes: Jannis Straube (Copenhagen), Vesa Havurinne (Aveiro), Laura Laihonen & Pablo Ortega Martínez (Turku @utu.fi)👏
Kudos to all participants🎉
See you in Umeå next time!
Kudos to all participants🎉
See you in Umeå next time!
October 25, 2025 at 7:08 AM
Warm congratulations to the young scientists recipients of the 2025 Nordic Photosynthesis community prizes: Jannis Straube (Copenhagen), Vesa Havurinne (Aveiro), Laura Laihonen & Pablo Ortega Martínez (Turku @utu.fi)👏
Kudos to all participants🎉
See you in Umeå next time!
Kudos to all participants🎉
See you in Umeå next time!
White beaked dolphins breach beside our boat in the North Atlantic as snowcapped peaks of Arctic fjords rise into clouds.
October 24, 2025 at 7:49 AM
White beaked dolphins breach beside our boat in the North Atlantic as snowcapped peaks of Arctic fjords rise into clouds.
In Cambridge celebrating 25 years of ribosome structure studies. Wonderful to reconnect with friends, pioneers of the field, and engage with brilliant young scientists. Proud to be part of this community. Thank you @mrclmb.bsky.social for the amazing event! Great photos by Song, Nenad and Shaoxia
September 23, 2025 at 2:26 AM
In Cambridge celebrating 25 years of ribosome structure studies. Wonderful to reconnect with friends, pioneers of the field, and engage with brilliant young scientists. Proud to be part of this community. Thank you @mrclmb.bsky.social for the amazing event! Great photos by Song, Nenad and Shaoxia
1973: Max Perutz explains the solution of hemoglobin. 53 years later, we’re still waiting for someone to solve the missing pointer
September 9, 2025 at 11:42 PM
1973: Max Perutz explains the solution of hemoglobin. 53 years later, we’re still waiting for someone to solve the missing pointer
A dramatic blood moon is lighting up the sky above Churchill College as Venki @mrclmb.bsky.social delivers the plenary on ribosome synthesis, a memorable alignment of breakthrough in structural biology and the cosmos tonight.
September 7, 2025 at 7:53 PM
A dramatic blood moon is lighting up the sky above Churchill College as Venki @mrclmb.bsky.social delivers the plenary on ribosome synthesis, a memorable alignment of breakthrough in structural biology and the cosmos tonight.
Its evolution involved acquiring exons, an intron, and a critical boost: a MITE transposon that jumped into its promoter turning up its expression.
Ironically, it became a repressor that shuts down the production of eugenol. Roses with working SCREP are silent, those where it's broken are fragrant.
Ironically, it became a repressor that shuts down the production of eugenol. Roses with working SCREP are silent, those where it's broken are fragrant.
September 3, 2025 at 1:40 AM
Its evolution involved acquiring exons, an intron, and a critical boost: a MITE transposon that jumped into its promoter turning up its expression.
Ironically, it became a repressor that shuts down the production of eugenol. Roses with working SCREP are silent, those where it's broken are fragrant.
Ironically, it became a repressor that shuts down the production of eugenol. Roses with working SCREP are silent, those where it's broken are fragrant.
The scent of silence! Cool research in Cell @cellpress.bsky.social to brighten up your day🌹. The mystery of why some roses are fragrant and others aren't has an answer. It's called SCREP: a rose-specific gene that evolved from non-coding DNA 16.8 million years ago 👇
September 3, 2025 at 1:40 AM
The scent of silence! Cool research in Cell @cellpress.bsky.social to brighten up your day🌹. The mystery of why some roses are fragrant and others aren't has an answer. It's called SCREP: a rose-specific gene that evolved from non-coding DNA 16.8 million years ago 👇
Stunning cryo-ET from Peijun Zhang lab: Direct visualization of HIV-1 nuclear import!
Hundreds of viral cores captured entering the nucleus. The NPC dilates to let the capsid through. A masterclass in correlative microscopy that makes it quantitative. A leap for structural virology! @emboreports.org
Hundreds of viral cores captured entering the nucleus. The NPC dilates to let the capsid through. A masterclass in correlative microscopy that makes it quantitative. A leap for structural virology! @emboreports.org
August 29, 2025 at 1:42 PM
Stunning cryo-ET from Peijun Zhang lab: Direct visualization of HIV-1 nuclear import!
Hundreds of viral cores captured entering the nucleus. The NPC dilates to let the capsid through. A masterclass in correlative microscopy that makes it quantitative. A leap for structural virology! @emboreports.org
Hundreds of viral cores captured entering the nucleus. The NPC dilates to let the capsid through. A masterclass in correlative microscopy that makes it quantitative. A leap for structural virology! @emboreports.org
Mitochondrial transfer is a fascinating phenomenon where cells shuttle mitos. The therapeutic potential is compelling and observational science is solid but the mechanism is a black box.
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
August 29, 2025 at 11:01 AM
Mitochondrial transfer is a fascinating phenomenon where cells shuttle mitos. The therapeutic potential is compelling and observational science is solid but the mechanism is a black box.
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
Excellent Viewpoint in @naturemetabolism.bsky.social breaks down one of cell biology’s biggest emerging mysteries
Fantastic studies presented by young scientists today: @noodlyscientist.bsky.social, @aliciakmichael.bsky.social, @sramundo.bsky.social, @florentwaltz.bsky.social.
Beautifully orchestrated by @cellarchlab.com
What a treat here in Münster @uni-muenster.de!
Beautifully orchestrated by @cellarchlab.com
What a treat here in Münster @uni-muenster.de!
August 28, 2025 at 1:23 PM
Fantastic studies presented by young scientists today: @noodlyscientist.bsky.social, @aliciakmichael.bsky.social, @sramundo.bsky.social, @florentwaltz.bsky.social.
Beautifully orchestrated by @cellarchlab.com
What a treat here in Münster @uni-muenster.de!
Beautifully orchestrated by @cellarchlab.com
What a treat here in Münster @uni-muenster.de!
Delighted to be appointed Honorary Visiting Chair Professor at Wuhan Agricultural University. This recognises our work in bioenergetics and opens exciting opportunities for international cryo-EM collaboration and joint supervision of PhD students.
August 20, 2025 at 4:10 AM
Delighted to be appointed Honorary Visiting Chair Professor at Wuhan Agricultural University. This recognises our work in bioenergetics and opens exciting opportunities for international cryo-EM collaboration and joint supervision of PhD students.
Dedicated my talk at the opening evening of Biophysical Society proton meeting to Karen Davies.
Karen's work shaped the field of bioenergetics from solving the horizontal subunit-a of ATP synthase to the structures of photosynthetic CI and more. She was a brilliant scientist, mentor and communicator
Karen's work shaped the field of bioenergetics from solving the horizontal subunit-a of ATP synthase to the structures of photosynthetic CI and more. She was a brilliant scientist, mentor and communicator
August 4, 2025 at 11:55 PM
Dedicated my talk at the opening evening of Biophysical Society proton meeting to Karen Davies.
Karen's work shaped the field of bioenergetics from solving the horizontal subunit-a of ATP synthase to the structures of photosynthetic CI and more. She was a brilliant scientist, mentor and communicator
Karen's work shaped the field of bioenergetics from solving the horizontal subunit-a of ATP synthase to the structures of photosynthetic CI and more. She was a brilliant scientist, mentor and communicator
Your sleep pressure is powered by your mitochondria! Sleep, energy, and ageing are all connected through mitochondrial bioenergetics in neurons. Brilliant work from Gero Miesenböck’s lab, just out in Nature @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 16, 2025 at 10:57 PM
Your sleep pressure is powered by your mitochondria! Sleep, energy, and ageing are all connected through mitochondrial bioenergetics in neurons. Brilliant work from Gero Miesenböck’s lab, just out in Nature @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Thank you very much for highlighting @beatascienceart.bsky.social illustration of our study on mitoribosome evolution and for explaining the work behind it. It was a wonderful collaboration, and still my favourite cover! @molbioevol.bsky.social
Exciting to see how art and science come together
Exciting to see how art and science come together
July 14, 2025 at 7:40 PM
Thank you very much for highlighting @beatascienceart.bsky.social illustration of our study on mitoribosome evolution and for explaining the work behind it. It was a wonderful collaboration, and still my favourite cover! @molbioevol.bsky.social
Exciting to see how art and science come together
Exciting to see how art and science come together
Science builds bridges🇮🇷🤝🇮🇱
Join me in welcoming our new postdoc Vida who brings PhD in plant sciences and will contribute to new bioenergetic studies. Vida is from Tabriz where her family's lives were disrupted by war. Thankfully no casualties, but career delays to her siblings and psychological toll
Join me in welcoming our new postdoc Vida who brings PhD in plant sciences and will contribute to new bioenergetic studies. Vida is from Tabriz where her family's lives were disrupted by war. Thankfully no casualties, but career delays to her siblings and psychological toll
July 11, 2025 at 4:06 AM
Science builds bridges🇮🇷🤝🇮🇱
Join me in welcoming our new postdoc Vida who brings PhD in plant sciences and will contribute to new bioenergetic studies. Vida is from Tabriz where her family's lives were disrupted by war. Thankfully no casualties, but career delays to her siblings and psychological toll
Join me in welcoming our new postdoc Vida who brings PhD in plant sciences and will contribute to new bioenergetic studies. Vida is from Tabriz where her family's lives were disrupted by war. Thankfully no casualties, but career delays to her siblings and psychological toll
The unique iso-fucoxanthin was modeled into an elongated non-protein density associated with Chl a1277. Its second ring corresponds to a cyclopentane (blue) instead of the canonical epoxy group found in typical fucoxanthin (yellow). This distinct feature identifies it as a novel isoform! 9/10
July 7, 2025 at 6:03 AM
The unique iso-fucoxanthin was modeled into an elongated non-protein density associated with Chl a1277. Its second ring corresponds to a cyclopentane (blue) instead of the canonical epoxy group found in typical fucoxanthin (yellow). This distinct feature identifies it as a novel isoform! 9/10
We also identify previously unreported features in PSI: 1) split subunit PsaA with a new chlorophyll inserted between the split domains, patched by subunit PsaV; 2) a unique iso-fucoxanthin bound to PsaB; 3) extended PsaF with an additional TMH coordinating an extra chlorophyll. 8/10
July 7, 2025 at 6:03 AM
We also identify previously unreported features in PSI: 1) split subunit PsaA with a new chlorophyll inserted between the split domains, patched by subunit PsaV; 2) a unique iso-fucoxanthin bound to PsaB; 3) extended PsaF with an additional TMH coordinating an extra chlorophyll. 8/10
These structural adaptations include variable elements that mediate contacts with PSI core components, and as a result individual FCP proteins adopt diverse orientations and form specific configurations of functionally coupled chlorophylls for intersubunit energy pathways. 7/10
July 7, 2025 at 6:03 AM
These structural adaptations include variable elements that mediate contacts with PSI core components, and as a result individual FCP proteins adopt diverse orientations and form specific configurations of functionally coupled chlorophylls for intersubunit energy pathways. 7/10
The antenna system includes five fucoxanthin-chlorophyll proteins (FCPs). Each FCP has evolved a structurally distinct interface to complement the local topology and pigment architecture of its corresponding PSI core docking site. This co-evolution allows to maintain efficient energy transfer 6/10
July 7, 2025 at 6:03 AM
The antenna system includes five fucoxanthin-chlorophyll proteins (FCPs). Each FCP has evolved a structurally distinct interface to complement the local topology and pigment architecture of its corresponding PSI core docking site. This co-evolution allows to maintain efficient energy transfer 6/10