Didier Mazel
@amazeld.bsky.social
Bacterial geneticist, Prof @ Institut Pasteur.
A key observation, explaining the easiness of cassette exchange among vibrios! Another brick from our lab. Kudos @kdebatisse.bsky.social and @celineloot.bsky.social as well as @eloilittner.bsky.social and @epcrocha.bsky.social !
November 18, 2025 at 4:45 PM
A key observation, explaining the easiness of cassette exchange among vibrios! Another brick from our lab. Kudos @kdebatisse.bsky.social and @celineloot.bsky.social as well as @eloilittner.bsky.social and @epcrocha.bsky.social !
Reposted by Didier Mazel
Congratulations to PhD students Jasmin Ostermayer and Noa Guzzi (co–first authors 🎉), together with Jakub Czarnecki and Alfonso Soler-Bistué, for compressing the diverse, lineage-wide literature on large extrachromosomal replicons into <5000 words and 80 references 😅
August 20, 2025 at 3:46 PM
Congratulations to PhD students Jasmin Ostermayer and Noa Guzzi (co–first authors 🎉), together with Jakub Czarnecki and Alfonso Soler-Bistué, for compressing the diverse, lineage-wide literature on large extrachromosomal replicons into <5000 words and 80 references 😅
Reposted by Didier Mazel
Our paper is published back2back with one from @amazeld.bsky.social and @epcrocha.bsky.social labs where @baptistedarracq.bsky.social, @eloilittner.bsky.social and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems. www.science.org/doi/10.1126/...
Sedentary chromosomal integrons as biobanks of bacterial antiphage defense systems
Integrons are genetic systems that drive bacterial adaptation by acquiring, expressing, and shuffling gene cassettes. While mobile integrons are well known for spreading antibiotic resistance genes, t...
www.science.org
May 8, 2025 at 8:27 PM
Our paper is published back2back with one from @amazeld.bsky.social and @epcrocha.bsky.social labs where @baptistedarracq.bsky.social, @eloilittner.bsky.social and co. show that Sedentary Chromosomal Integrons are biobanks of phage defense systems. www.science.org/doi/10.1126/...
Reposted by Didier Mazel
7/ The actors (II)
This was truly a memorable collaborative experience, involving multiple labs: Eric Le Cam (Gustave Roussy), Ole Skovgaard @oskov.bsky.social (Roskilde University), Abel Garcia-Pino (Université libre de Bruxelles), and the Mazel team @amazeld.bsky.social at Institut Pasteur !
This was truly a memorable collaborative experience, involving multiple labs: Eric Le Cam (Gustave Roussy), Ole Skovgaard @oskov.bsky.social (Roskilde University), Abel Garcia-Pino (Université libre de Bruxelles), and the Mazel team @amazeld.bsky.social at Institut Pasteur !
January 9, 2025 at 12:49 PM
7/ The actors (II)
This was truly a memorable collaborative experience, involving multiple labs: Eric Le Cam (Gustave Roussy), Ole Skovgaard @oskov.bsky.social (Roskilde University), Abel Garcia-Pino (Université libre de Bruxelles), and the Mazel team @amazeld.bsky.social at Institut Pasteur !
This was truly a memorable collaborative experience, involving multiple labs: Eric Le Cam (Gustave Roussy), Ole Skovgaard @oskov.bsky.social (Roskilde University), Abel Garcia-Pino (Université libre de Bruxelles), and the Mazel team @amazeld.bsky.social at Institut Pasteur !
Reposted by Didier Mazel
8/ 🌍 Broader implications
This study not only highlights the elegant coordination of replication between Chr1 and Chr2 in Vibrio but the mechanism described here may reflect a broader strategy used by bacteria to integrate and stabilize secondary replicons derived from ancestral plasmids.
This study not only highlights the elegant coordination of replication between Chr1 and Chr2 in Vibrio but the mechanism described here may reflect a broader strategy used by bacteria to integrate and stabilize secondary replicons derived from ancestral plasmids.
January 9, 2025 at 12:51 PM
8/ 🌍 Broader implications
This study not only highlights the elegant coordination of replication between Chr1 and Chr2 in Vibrio but the mechanism described here may reflect a broader strategy used by bacteria to integrate and stabilize secondary replicons derived from ancestral plasmids.
This study not only highlights the elegant coordination of replication between Chr1 and Chr2 in Vibrio but the mechanism described here may reflect a broader strategy used by bacteria to integrate and stabilize secondary replicons derived from ancestral plasmids.