Amar Sahay
@amarsahay.bsky.social
Professor @ MGH & Harvard Medical School. Hippocampus + Cognition. www.sahaylab.com
Engineering strategies to restore, maintain and enhance cognition since 2011.
(U)Marathoner. Shark diver. Husband. Dad of human and wirehaired doxies
Engineering strategies to restore, maintain and enhance cognition since 2011.
(U)Marathoner. Shark diver. Husband. Dad of human and wirehaired doxies
Evolution is parsimonious in circuit usage.CA2 contributes to spatial and social cognition. TLTW IMO: Oxtr + V1br may bias CA2 recruitment to social cues to support social memory. See this study w/ Amigo2 Cre mice.https://link.springer.com/article/10.1007/s12264-025-01535-9
November 25, 2025 at 9:57 PM
Evolution is parsimonious in circuit usage.CA2 contributes to spatial and social cognition. TLTW IMO: Oxtr + V1br may bias CA2 recruitment to social cues to support social memory. See this study w/ Amigo2 Cre mice.https://link.springer.com/article/10.1007/s12264-025-01535-9
Barren, grey and yet rewarding to the senses on a morning run!
November 25, 2025 at 8:59 PM
Barren, grey and yet rewarding to the senses on a morning run!
Cant beat this weather for a run!
November 17, 2025 at 8:48 PM
Cant beat this weather for a run!
The irresistible allure of running thru florid imagery with Van Halen, White Lion, Joan Jett, Joy Division, REM, Glass Tiger, and “It’s my life” triggered memory recall. Natural Synesthesia!
November 8, 2025 at 3:38 PM
The irresistible allure of running thru florid imagery with Van Halen, White Lion, Joan Jett, Joy Division, REM, Glass Tiger, and “It’s my life” triggered memory recall. Natural Synesthesia!
Hey German to English Google translate, there is enough persecution in this world. Please dont persecute my delivery.
November 5, 2025 at 1:45 PM
Hey German to English Google translate, there is enough persecution in this world. Please dont persecute my delivery.
Rare afternoon trail run. Too beautiful to resist.
October 25, 2025 at 9:46 PM
Rare afternoon trail run. Too beautiful to resist.
Good morning from a recent memory.
October 21, 2025 at 10:54 AM
Good morning from a recent memory.
Happy Diwali to all those who observe it. Diwali signifies the victory of light over darkness, good over evil, and knowledge over ignorance. We will all benefit.
October 19, 2025 at 10:11 PM
Happy Diwali to all those who observe it. Diwali signifies the victory of light over darkness, good over evil, and knowledge over ignorance. We will all benefit.
Damn! Cant beat these fall morning runs! With @singhcredible.bsky.social
Thx for chatting about trials and tribulations of ultras, fueling, and running for life.
Thx for chatting about trials and tribulations of ultras, fueling, and running for life.
October 19, 2025 at 2:16 PM
Damn! Cant beat these fall morning runs! With @singhcredible.bsky.social
Thx for chatting about trials and tribulations of ultras, fueling, and running for life.
Thx for chatting about trials and tribulations of ultras, fueling, and running for life.
“The threat of AGI cannot be overstated”
~Dachshund Community notes, Regional Chapter.
~Dachshund Community notes, Regional Chapter.
October 16, 2025 at 12:33 PM
“The threat of AGI cannot be overstated”
~Dachshund Community notes, Regional Chapter.
~Dachshund Community notes, Regional Chapter.
The concomitant warmth of fire and human-gaze triggered oxytocin is thought to have transformed the beastly wolf into domesticated hound.
October 11, 2025 at 10:17 PM
The concomitant warmth of fire and human-gaze triggered oxytocin is thought to have transformed the beastly wolf into domesticated hound.
Transitions. Imminence. Fleeting hues.
October 11, 2025 at 9:03 PM
Transitions. Imminence. Fleeting hues.
Cider donut (mini) while taking in foliage in southern VT after college reunion-Check. #Fallnevergetsold
October 5, 2025 at 4:11 PM
Cider donut (mini) while taking in foliage in southern VT after college reunion-Check. #Fallnevergetsold
Happy Birthday Mahatma Gandhi. May we all take a moment to learn from you today.
October 2, 2025 at 11:52 AM
Happy Birthday Mahatma Gandhi. May we all take a moment to learn from you today.
Rest in peace my friend. Your contributions to humanity and your humanity will always be cherished. We will pay it forward.
September 23, 2025 at 10:52 AM
Rest in peace my friend. Your contributions to humanity and your humanity will always be cherished. We will pay it forward.
Aug 9, 2023 Diving with sand tigers at the U-352, German U-boat, wreck off the North Carolina coast.
September 13, 2025 at 12:24 AM
Aug 9, 2023 Diving with sand tigers at the U-352, German U-boat, wreck off the North Carolina coast.
Battle scars like a great white’s. ❤️ distance running and shark diving!
September 12, 2025 at 11:57 PM
Battle scars like a great white’s. ❤️ distance running and shark diving!
Learned a lot about myself and training to push the “limit”. Need to work more on fueling (carb intake). Running community is uplifting, in the pain cave together until the end when we revel in the journey completed. W/ @singhcredible.bsky.social
and Victor, friends on this journey.
and Victor, friends on this journey.
September 7, 2025 at 3:51 PM
Learned a lot about myself and training to push the “limit”. Need to work more on fueling (carb intake). Running community is uplifting, in the pain cave together until the end when we revel in the journey completed. W/ @singhcredible.bsky.social
and Victor, friends on this journey.
and Victor, friends on this journey.
Hardest race of my life. Finished strong with other inspiring runners. 8.5 hours of 🏃🏽♀️ 70-82F /94% H/2500 ft elevation. 25 x 100 mg salt intake to reverse two bouts of leg cramps. So much time alone in these beautiful woods avoiding rabbit holes of weakness..
September 7, 2025 at 3:50 PM
Hardest race of my life. Finished strong with other inspiring runners. 8.5 hours of 🏃🏽♀️ 70-82F /94% H/2500 ft elevation. 25 x 100 mg salt intake to reverse two bouts of leg cramps. So much time alone in these beautiful woods avoiding rabbit holes of weakness..
Never thought Id lose a Saturday to an UltraM.The entry/exit from woods in Ultras is such a primal attraction even if the last stretch is a pain cave. So much was mental (not giving up) and calmly managing challenge (salt, cramps, roots/rocks) 50K Carlisle Fall Classic Done! 1/n
September 7, 2025 at 3:49 PM
Never thought Id lose a Saturday to an UltraM.The entry/exit from woods in Ultras is such a primal attraction even if the last stretch is a pain cave. So much was mental (not giving up) and calmly managing challenge (salt, cramps, roots/rocks) 50K Carlisle Fall Classic Done! 1/n
GM. Think deeply about problems you care about. Focus on relationships that matter.
August 31, 2025 at 12:31 PM
GM. Think deeply about problems you care about. Focus on relationships that matter.
As the UTMBWorldSeries gladiators slug it out, I revel in the intoxication of Acadia morning dew!
August 30, 2025 at 1:34 PM
As the UTMBWorldSeries gladiators slug it out, I revel in the intoxication of Acadia morning dew!