Alister Burt
@alisterburt.bsky.social
Computational Cryo-EM/ET at Genentech
Love people, the outdoors and building stuff
Complexity is the enemy
All opinions my own
Love people, the outdoors and building stuff
Complexity is the enemy
All opinions my own
Big thanks to Alberto, @jeff.cuchazinteractive.org and others for amazing hospitality and discussions! I’ve come away super excited about the future of cryo-EM :-)
November 20, 2025 at 1:53 AM
Big thanks to Alberto, @jeff.cuchazinteractive.org and others for amazing hospitality and discussions! I’ve come away super excited about the future of cryo-EM :-)
Thank you for the kind words! I’m working to have it out ASAP 🙂
November 18, 2025 at 9:51 AM
Thank you for the kind words! I’m working to have it out ASAP 🙂
At least for metformin the target (complex I) was well established… not always true!
November 15, 2025 at 10:54 PM
At least for metformin the target (complex I) was well established… not always true!
Aw, thank you! 🥹
November 15, 2025 at 6:56 PM
Aw, thank you! 🥹
Great write up! Thank you for sharing.
Totally agree the learning curve is too steep for many, the happy path for your lab members avoids environment hell by using uv to run scripts which have declared their dependencies - the env is managed for you in the background
docs.astral.sh/uv/guides/sc...
Totally agree the learning curve is too steep for many, the happy path for your lab members avoids environment hell by using uv to run scripts which have declared their dependencies - the env is managed for you in the background
docs.astral.sh/uv/guides/sc...
Running scripts | uv
A guide to using uv to run Python scripts, including support for inline dependency metadata, reproducible scripts, and more.
docs.astral.sh
November 15, 2025 at 6:40 PM
Great write up! Thank you for sharing.
Totally agree the learning curve is too steep for many, the happy path for your lab members avoids environment hell by using uv to run scripts which have declared their dependencies - the env is managed for you in the background
docs.astral.sh/uv/guides/sc...
Totally agree the learning curve is too steep for many, the happy path for your lab members avoids environment hell by using uv to run scripts which have declared their dependencies - the env is managed for you in the background
docs.astral.sh/uv/guides/sc...
😂😂😂 don’t give them ideas
November 11, 2025 at 5:08 AM
😂😂😂 don’t give them ideas
great tip, thanks!
November 1, 2025 at 6:54 PM
great tip, thanks!
“are we still living off the dividends from ideas that were nurtured, and risks that were taken, a half century ago”
November 1, 2025 at 5:28 PM
“are we still living off the dividends from ideas that were nurtured, and risks that were taken, a half century ago”
the bot!! Thank you 🙏
November 1, 2025 at 5:27 PM
the bot!! Thank you 🙏