3-Why does this matter?
Heat stress doesn’t just tweak physiology—it can reshape heritable genomic features, influencing adaptation across generations.

www.biorxiv.org/content/10.1...

2- The hot queen effect:
♀ Ovaries = resilient!
✅ Strong miRNA/piRNA defence against transposable elements
✅ Boosted protein-processing pathways

♂ Testes = vulnerable
❌ Reduced piRNA output
❌ More TE insertions + immune signatures

1-We tested zebrafish germ cells under elevated temperatures and found sex-specific molecular strategies for survival.
🧬 Genomics
🧪 Transcriptomics
🎯 Small RNAs

Takeaway: even “simple” dietary fibres can ripple across the microbiota–gut–brain axis — and dosage + sex differences matter. 🐟

And it wasn’t the same for everyone:
♀️ High gum Arabic had negative impacts on female reproductive fitness.
♂️ But in males, effects were mostly beneficial.

🐟 Gum Arabic reshaped the gut microbiome (↓ Proteobacteria, ↑ Cetobacterium).
🧠 Changed brain metabolism (↑ acetate at high doses).
🧬 Altered gene expression linked to appetite + energy use.

Thank you, what a cool session!

Thanks 🐠😃