Alessio Ciulli
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alessiociulli.bsky.social
Alessio Ciulli
@alessiociulli.bsky.social
Professor, Founder and Director of the Centre for Targeted Protein Degradation at the University of Dundee. We develop molecules that induce protein interactions and degradation
Reposted by Alessio Ciulli
An absolute pleasure to work with all co-authors on this study: from @alessiociulli.bsky.social’s lab (the 🤝 House of VHL 🤝) @alesalerno.bsky.social & Gajanan Sathe – and our wonderful collaboration Graham Marsh and Hannah Maple from Tocris Bio-Techne
November 19, 2025 at 5:02 PM
Great to see you Julien!
October 18, 2025 at 10:54 PM
Incredibly grateful and thankful for the resilience and brilliance of my postdocs @mariarrios.bsky.social and Conner Craigon, the incredible support by @b45her71.bsky.social and Mark Nakasone, and the talented team at Tocris led by Hannah Maple. Brilliant team-science!
April 9, 2025 at 10:15 PM
We love it as it works real well! We are curious to hear your thoughts and learn feedback as you try it out for your own research, so do reach out we are happy to share all reagents and ahead of the key products becoming available via Tocris @biotechne.bsky.social
April 9, 2025 at 10:13 PM
Thank you Biochemical Society it is an honour on behalf of all of the team present and past member to receive this award. Everyone at @dundeeuni.bsky.social and @boehringerglobal.bsky.social are very proud of this recognition of our model reimagining how academia and industry work together
April 9, 2025 at 10:07 PM
Well done @holmqvist89.bsky.social and @nurkocaturk.bsky.social - dream team! ;)
March 10, 2025 at 6:22 PM
Go Ale go! 💪👍🙏
January 25, 2025 at 9:04 AM
Nice work team!
January 11, 2025 at 9:55 AM
Our privilege to coauthor a paper with the inimitable @giuliosupertifurga.bsky.social and his amazing team! Thank you 🙏 Giulio for the great collaboration and Kudos to Gernot in GSF Lab and Conner and Diane in my Lab and to all the coauthors. Macrocyclic PROTAC chemistry by @yutingcao.bsky.social
January 7, 2025 at 10:00 PM
Cool to learn you like it! 👍
December 22, 2024 at 8:35 AM
Loads! The idea first emerged ~7y ago at a group meeting, @andre-head.bsky.social recalls well. He was keen but had his hands full. 4 years later until anyone took the suggestion seriously (Claudia) she had many plates spinning too but @alesalerno.bsky.social had just joined and really run with it!
December 22, 2024 at 12:17 AM
Last Christmas, Claudia and Alessandra gave us DCC PROTACs doi.org/10.26434/che... .. This year, to keep us in the theme, they together with Lianne are giving us something special.. 🎶 Big kudos to them all and great job @alesalerno.bsky.social for championing this. Let us know your thoughts! 5/5
Ternary Complex-Directed Dynamic Combinatorial Chemistry Enables Discovery of Potent VHL Homo-PROTACs
Dynamic combinatorial chemistry (DCC) leverages a reversible reaction to generate compound libraries from constituting building blocks under thermodynamic control. The position of this equilibrium can...
doi.org
December 21, 2024 at 11:48 PM