Alan Gutman-Wei
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alangutmanwei.bsky.social
Alan Gutman-Wei
@alangutmanwei.bsky.social
postdoc @ hobertlab.org studying synaptic remodeling in the C elegans nervous system | PhD neuroscience @jhu.edu
Synaptogenesis is selective for parvalbumin interneurons within layer 6, and in translaminar connections to layer 4. This is despite these interneurons being far less abundant than neighboring excitatory neurons in both layers (6/7)
August 19, 2025 at 4:22 PM
Do excitatory neurons selectively innervate their targets from the beginning, or make synapses promiscuously and then eliminate the off-target ones? We find that layer 6 corticothalamic neurons selectively form functional synapses to parvalbumin interneurons (5/7)
August 19, 2025 at 4:22 PM
How does developmental neuronal activity affect axon arbor growth? We found that hyperpolarizing layer 6 corticothalamic neurons increased axon arbor elaboration specifically in layer 6, but not in layers 4 or 5 (4/7)
August 19, 2025 at 4:22 PM
When and how do layer 6 corticothalamic neurons elaborate their intracortical axon branches? Using sparse labeling and lightsheet imaging we found two stages of outgrowth separated by a period of stasis in the first two postnatal weeks (3/7)
August 19, 2025 at 4:22 PM