Adam Steinbrenner
@adsteinbrenner.bsky.social
Associate Prof @UWBiology Seattle. How do plants recognize and resist pests 🐛? We study receptor function + evolution in plant innate immunity. steinbrennerlab.org
Happy to support this letter. My grad's situation here: bsky.app/profile/did:...
Very frustrated with NSF GRFP. A 2nd year grad now ineligible after postponing last year.
Her pre-grad app was rejected without review for mentioning crop impacts.
I'm a previous recipient and served many years as a reviewer. The fellowship needs serious reform, not half-baked solicitation changes
Her pre-grad app was rejected without review for mentioning crop impacts.
I'm a previous recipient and served many years as a reviewer. The fellowship needs serious reform, not half-baked solicitation changes
September 26, 2025 at 5:19 PM
Happy to support this letter. My grad's situation here: bsky.app/profile/did:...
We hope the work is interesting to those trying to translate PAMP responses to pest and pathogen resistance!
September 5, 2025 at 3:29 AM
We hope the work is interesting to those trying to translate PAMP responses to pest and pathogen resistance!
This study inspired lots more❓for us
What is a sufficient level of PRR expression? Analyses of NLR expression from Krasileva lab (ref 52) were interesting here
How does early "PTI response" translate to resistance? Great review from Balint-Kurti lab (ref 43) helped us interpret our findings
What is a sufficient level of PRR expression? Analyses of NLR expression from Krasileva lab (ref 52) were interesting here
How does early "PTI response" translate to resistance? Great review from Balint-Kurti lab (ref 43) helped us interpret our findings
September 5, 2025 at 3:29 AM
This study inspired lots more❓for us
What is a sufficient level of PRR expression? Analyses of NLR expression from Krasileva lab (ref 52) were interesting here
How does early "PTI response" translate to resistance? Great review from Balint-Kurti lab (ref 43) helped us interpret our findings
What is a sufficient level of PRR expression? Analyses of NLR expression from Krasileva lab (ref 52) were interesting here
How does early "PTI response" translate to resistance? Great review from Balint-Kurti lab (ref 43) helped us interpret our findings
What about the caterpillars? We generated low expression (inr-2 allele) near-isogenic lines, but interestingly, In11 pretreatment still protected these plants from attack.
We conclude that insensitivity with common lab assays for PTI does not necessary correspond with resistance.
We conclude that insensitivity with common lab assays for PTI does not necessary correspond with resistance.
September 5, 2025 at 3:29 AM
What about the caterpillars? We generated low expression (inr-2 allele) near-isogenic lines, but interestingly, In11 pretreatment still protected these plants from attack.
We conclude that insensitivity with common lab assays for PTI does not necessary correspond with resistance.
We conclude that insensitivity with common lab assays for PTI does not necessary correspond with resistance.
Promoter alleles from different In11-reponsive or non-responsive varieties corresponded with strength driving luciferase expression in transient expression assays. Thus, low INR expression seems to mediate insensitivity to In11 in lab conditions.
September 5, 2025 at 3:29 AM
Promoter alleles from different In11-reponsive or non-responsive varieties corresponded with strength driving luciferase expression in transient expression assays. Thus, low INR expression seems to mediate insensitivity to In11 in lab conditions.
We found just a few insensitive accessions among hundreds of tested USDA-GRIN varieties. One variety was associated with lower expression of the INR gene. The low expression INR haplotype turned out to be locally prevalent in varieties from Jujuy province in Argentina.
September 5, 2025 at 3:29 AM
We found just a few insensitive accessions among hundreds of tested USDA-GRIN varieties. One variety was associated with lower expression of the INR gene. The low expression INR haplotype turned out to be locally prevalent in varieties from Jujuy province in Argentina.
Legumes in the subtribe Phaseolinae evolved the INR immune receptor to detect attack by caterpillars through In11 peptide in their spit.
INR is strikingly conserved in legumes. 364 tested varieties of cowpea from our original 2020 GWAS are sensitive to In11!
elifesciences.org/articles/81050
INR is strikingly conserved in legumes. 364 tested varieties of cowpea from our original 2020 GWAS are sensitive to In11!
elifesciences.org/articles/81050
Evolutionary gain and loss of a plant pattern-recognition receptor for HAMP recognition
A plant immune receptor evolved recognition of caterpillar peptides through key molecular changes.
elifesciences.org
September 5, 2025 at 3:29 AM
Legumes in the subtribe Phaseolinae evolved the INR immune receptor to detect attack by caterpillars through In11 peptide in their spit.
INR is strikingly conserved in legumes. 364 tested varieties of cowpea from our original 2020 GWAS are sensitive to In11!
elifesciences.org/articles/81050
INR is strikingly conserved in legumes. 364 tested varieties of cowpea from our original 2020 GWAS are sensitive to In11!
elifesciences.org/articles/81050