Lorenz Adlung Lab
@adlunglab.com
Data-driven & knowledge-based. Rooted in Hamburg, Germany.
Adipose and/or Systems Biology + Inflammation.
Account handled by π @LorenzAdlung.com
www.adlunglab.com
Adipose and/or Systems Biology + Inflammation.
Account handled by π @LorenzAdlung.com
www.adlunglab.com
This work points to a future of personalised interventions: pairing probiotics with human milk oligosaccharides-rich human milk to support beneficial microbial metabolism.
doi.org/10.1016/j.ce... 🧪
🏁
5/5
doi.org/10.1016/j.ce... 🧪
🏁
5/5
Bacterial metabolite patterns of infants receiving multi-strain probiotics and risk of late-onset sepsis
The effect of multi-strain probiotics containing Bifidobacterium longum (B. longum) on late-onset sepsis (LOS) risk in very-low-birth-weight infants (…
doi.org
November 18, 2025 at 9:01 AM
This work points to a future of personalised interventions: pairing probiotics with human milk oligosaccharides-rich human milk to support beneficial microbial metabolism.
doi.org/10.1016/j.ce... 🧪
🏁
5/5
doi.org/10.1016/j.ce... 🧪
🏁
5/5
These metabolites are thought to protect the gut barrier and regulate immune responses. Their absence suggests a breakdown in microbial metabolic function.
So, probiotics alone might not prevent sepsis. Instead monitoring gut metabolites could help flag infants at risk earlier.
4/5
So, probiotics alone might not prevent sepsis. Instead monitoring gut metabolites could help flag infants at risk earlier.
4/5
November 18, 2025 at 9:00 AM
These metabolites are thought to protect the gut barrier and regulate immune responses. Their absence suggests a breakdown in microbial metabolic function.
So, probiotics alone might not prevent sepsis. Instead monitoring gut metabolites could help flag infants at risk earlier.
4/5
So, probiotics alone might not prevent sepsis. Instead monitoring gut metabolites could help flag infants at risk earlier.
4/5
Their abundance alone is not sufficient, their metabolic functions matter. Infants who developed sepsis had lower gut levels of lactate and acetate, key fermentation products of B. longum.
So how are these metabolites linked to late-onset sepsis?
3/5
So how are these metabolites linked to late-onset sepsis?
3/5
November 18, 2025 at 9:00 AM
Their abundance alone is not sufficient, their metabolic functions matter. Infants who developed sepsis had lower gut levels of lactate and acetate, key fermentation products of B. longum.
So how are these metabolites linked to late-onset sepsis?
3/5
So how are these metabolites linked to late-onset sepsis?
3/5
Routine supplementation with B. longum and L. acidophilus boosted beneficial gut bacteria and lowered levels of antibiotic-resistant pathobionts like Klebsiella and S. haemolyticus.
But...
2/5
But...
2/5
November 18, 2025 at 9:00 AM
Routine supplementation with B. longum and L. acidophilus boosted beneficial gut bacteria and lowered levels of antibiotic-resistant pathobionts like Klebsiella and S. haemolyticus.
But...
2/5
But...
2/5
It's not publicly available, but I'll email you with some material (:
November 16, 2025 at 2:05 PM
It's not publicly available, but I'll email you with some material (:
Really cool, Daniel, and very useful – thanks a lot for providing the model and making it so accessible!
November 15, 2025 at 3:15 PM
Really cool, Daniel, and very useful – thanks a lot for providing the model and making it so accessible!
Yes, also the preprint is really great. I hope reviewers will appreciate it! 🤞
October 17, 2025 at 10:49 AM
Yes, also the preprint is really great. I hope reviewers will appreciate it! 🤞