Adam Cribbs
@adamcribbs.bsky.social
#MRC CDA fellow,
University of Oxford, long-read sequencing| single-cell technology development| multiple myeloma| bone cancer
University of Oxford, long-read sequencing| single-cell technology development| multiple myeloma| bone cancer
📢 New preprint alert!
We present UMIche, a modular, open-source platform to improve UMI-based molecular quantification in bulk and scRNA-seq data.
→ Integrated pipelines
→ Monomer & homotrimer UMIs
→ Deep learning-based simulation
🔗 doi.org/10.21203/rs....
We present UMIche, a modular, open-source platform to improve UMI-based molecular quantification in bulk and scRNA-seq data.
→ Integrated pipelines
→ Monomer & homotrimer UMIs
→ Deep learning-based simulation
🔗 doi.org/10.21203/rs....
May 6, 2025 at 9:19 AM
📢 New preprint alert!
We present UMIche, a modular, open-source platform to improve UMI-based molecular quantification in bulk and scRNA-seq data.
→ Integrated pipelines
→ Monomer & homotrimer UMIs
→ Deep learning-based simulation
🔗 doi.org/10.21203/rs....
We present UMIche, a modular, open-source platform to improve UMI-based molecular quantification in bulk and scRNA-seq data.
→ Integrated pipelines
→ Monomer & homotrimer UMIs
→ Deep learning-based simulation
🔗 doi.org/10.21203/rs....
Reposted by Adam Cribbs
Ever torn a tendon? Our study led by @joletmimpen.bsky.social discovered changes in fibroblast and immune cell populations that occur in quadriceps tendon tears.
Read more: doi.org/10.1113/JP28...
@sarahsnelling.bsky.social
@adamcribbs.bsky.social
Read more: doi.org/10.1113/JP28...
@sarahsnelling.bsky.social
@adamcribbs.bsky.social
April 16, 2025 at 8:47 AM
Ever torn a tendon? Our study led by @joletmimpen.bsky.social discovered changes in fibroblast and immune cell populations that occur in quadriceps tendon tears.
Read more: doi.org/10.1113/JP28...
@sarahsnelling.bsky.social
@adamcribbs.bsky.social
Read more: doi.org/10.1113/JP28...
@sarahsnelling.bsky.social
@adamcribbs.bsky.social
Reposted by Adam Cribbs
FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation https://www.biorxiv.org/content/10.1101/2025.03.06.641728v1
March 12, 2025 at 3:39 PM
FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation https://www.biorxiv.org/content/10.1101/2025.03.06.641728v1
We are pleased to share our latest preprint: "FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation". FlowAgent makes complex bioinformatics workflows accessible and adaptive using agentic #AI. #Bioinformatics www.biorxiv.org/content/10.1...
FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation
Reproducibility, automation, and flexibility remain persistent challenges in bioinformatics, where complex workflows require integration of diverse computational tools, rigorous quality control, and d...
www.biorxiv.org
March 12, 2025 at 12:07 PM
We are pleased to share our latest preprint: "FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation". FlowAgent makes complex bioinformatics workflows accessible and adaptive using agentic #AI. #Bioinformatics www.biorxiv.org/content/10.1...
Reposted by Adam Cribbs
Oooh! Oooh! I know! Mar-a-Lago.
March 7, 2025 at 10:30 PM
Oooh! Oooh! I know! Mar-a-Lago.
Bit late, but first paper of 2025. 🧬Enhancing #singlecell #transcriptomics: Our recent study introduces an interposed anchor strategy to improve gene expression profiles in droplet-based single-cell sequencing analyses. www.nature.com/articles/s42...
Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences - Communications Biology
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and ...
www.nature.com
February 16, 2025 at 10:47 AM
Bit late, but first paper of 2025. 🧬Enhancing #singlecell #transcriptomics: Our recent study introduces an interposed anchor strategy to improve gene expression profiles in droplet-based single-cell sequencing analyses. www.nature.com/articles/s42...
Reposted by Adam Cribbs
I was just told that I have to remove “climate” from the title of an ongoing grant if I want to keep it. And publications from that grant cannot include “climate” and other forbidden words. I can’t believe I’m writing this from the United States of America. #AcademicSky
Just received an email saying that it's not advisable to include the following words in future applications for research funding to the US DOT. Here we are.
February 10, 2025 at 9:00 PM
I was just told that I have to remove “climate” from the title of an ongoing grant if I want to keep it. And publications from that grant cannot include “climate” and other forbidden words. I can’t believe I’m writing this from the United States of America. #AcademicSky
Reposted by Adam Cribbs
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and feature detection for both short- and long-read methods.
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences - Communications Biology
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and ...
www.nature.com
January 17, 2025 at 2:16 PM
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and feature detection for both short- and long-read methods.
www.nature.com/articles/s42...
www.nature.com/articles/s42...