Antibiotic Steward 🅱️C🆔🅿️🌟
@absteward.bsky.social
Stay up-to-date in Infectious Diseases, Clinical Pharmacist, Antibiotics, #IDTwitter t✨p influencer #interstellar #dune
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
🌹❤️Misk #idsky #medsky #AMSsky #idxposts
Bassam Ghanem,PharmD MS BCPS BCIDP
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
🔗 [link] #idsky
www.amjmed.com/article/S000...
November 19, 2025 at 4:25 PM
🆕🔥🦴 Our 2025 Update to @wiki-guidelines.bsky.social for the Management of Pyogenic Osteomyelitis in Adults 🌟 @bradspellberg.bsky.social
🔗 [link] #idsky
www.amjmed.com/article/S000...
🔗 [link] #idsky
www.amjmed.com/article/S000...
Cross-reactivity of beta-lactams. A review of the beta-lactam cross-reactivity patterns based on key pharmacological structures and known clinical cross-reactivity #idsky
November 6, 2025 at 8:35 PM
Cross-reactivity of beta-lactams. A review of the beta-lactam cross-reactivity patterns based on key pharmacological structures and known clinical cross-reactivity #idsky
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
url: academic.oup.com/cid/article/...
November 6, 2025 at 8:09 PM
🆕🔥State-of-the-Art Review with 🌟s @trubianojason.bsky.social : Antibiotic Allergy—A Multidisciplinary Approach to Delabeling #idsky
url: academic.oup.com/cid/article/...
url: academic.oup.com/cid/article/...
🔥Meitheal Pharmaceuticals Receives Approval from the US FDA for CONTEPO™ (fosfomycin) for injection in Patients ≥ 18 Years Having Complicated Urinary Tract Infections (cUTI),Including Acute Pyelonephritis🔥#idsky
www.businesswire.com/news/home/20...
www.businesswire.com/news/home/20...
November 5, 2025 at 4:32 AM
🔥Meitheal Pharmaceuticals Receives Approval from the US FDA for CONTEPO™ (fosfomycin) for injection in Patients ≥ 18 Years Having Complicated Urinary Tract Infections (cUTI),Including Acute Pyelonephritis🔥#idsky
www.businesswire.com/news/home/20...
www.businesswire.com/news/home/20...
Updated nomenclature of common Candida species
Add Candida auris ⏭️Candidozyma auris.
The only one left is Candida albicans!
#IDsky
link.springer.com/article/10.1...
Add Candida auris ⏭️Candidozyma auris.
The only one left is Candida albicans!
#IDsky
link.springer.com/article/10.1...
October 23, 2025 at 11:21 PM
Updated nomenclature of common Candida species
Add Candida auris ⏭️Candidozyma auris.
The only one left is Candida albicans!
#IDsky
link.springer.com/article/10.1...
Add Candida auris ⏭️Candidozyma auris.
The only one left is Candida albicans!
#IDsky
link.springer.com/article/10.1...
🆕🌟Excellent review
Invasive candidiasis in intensive care medicine: shaping the future of diagnosis and therapy #IDSky #EMIMCC
link.springer.com/article/10.1...
Invasive candidiasis in intensive care medicine: shaping the future of diagnosis and therapy #IDSky #EMIMCC
link.springer.com/article/10.1...
October 23, 2025 at 11:18 PM
🆕🌟Excellent review
Invasive candidiasis in intensive care medicine: shaping the future of diagnosis and therapy #IDSky #EMIMCC
link.springer.com/article/10.1...
Invasive candidiasis in intensive care medicine: shaping the future of diagnosis and therapy #IDSky #EMIMCC
link.springer.com/article/10.1...
CDI recurrence affects about 14% to 16% of patients with CDI, and the risk of recurrence increases with each CDI episode
🆕💫🌟 JAMA Insights
Recurrent Clostridioides difficile Infections
🟢Epidemiology and Risk factors
🟢Diagnosis
🟢Treatment
#IDSky #EMIMCC
jamanetwork.com/journals/jam...
🆕💫🌟 JAMA Insights
Recurrent Clostridioides difficile Infections
🟢Epidemiology and Risk factors
🟢Diagnosis
🟢Treatment
#IDSky #EMIMCC
jamanetwork.com/journals/jam...
October 20, 2025 at 5:00 PM
CDI recurrence affects about 14% to 16% of patients with CDI, and the risk of recurrence increases with each CDI episode
🆕💫🌟 JAMA Insights
Recurrent Clostridioides difficile Infections
🟢Epidemiology and Risk factors
🟢Diagnosis
🟢Treatment
#IDSky #EMIMCC
jamanetwork.com/journals/jam...
🆕💫🌟 JAMA Insights
Recurrent Clostridioides difficile Infections
🟢Epidemiology and Risk factors
🟢Diagnosis
🟢Treatment
#IDSky #EMIMCC
jamanetwork.com/journals/jam...
🆕🔥Seminar
Community-acquired pneumonia @thelancet.com #IDSky #EMIMCC
www.thelancet.com/journals/lan...
Community-acquired pneumonia @thelancet.com #IDSky #EMIMCC
www.thelancet.com/journals/lan...
October 19, 2025 at 9:26 PM
🆕🔥Seminar
Community-acquired pneumonia @thelancet.com #IDSky #EMIMCC
www.thelancet.com/journals/lan...
Community-acquired pneumonia @thelancet.com #IDSky #EMIMCC
www.thelancet.com/journals/lan...
🆕🔥🔥CloCeBa RCT
Cloxacillin versus cefazolin for MSSA Bacteraemia
Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky
www.thelancet.com/journals/lan...
Cloxacillin versus cefazolin for MSSA Bacteraemia
Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky
www.thelancet.com/journals/lan...
October 19, 2025 at 4:34 AM
🆕🔥🔥CloCeBa RCT
Cloxacillin versus cefazolin for MSSA Bacteraemia
Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky
www.thelancet.com/journals/lan...
Cloxacillin versus cefazolin for MSSA Bacteraemia
Cefazolin has a non-inferior efficacy regarding mortality, microbiological or clinical endpoints and was associated with a lower rate of serious adverse events #IDSky
www.thelancet.com/journals/lan...
There is still a widespread belief that fever is harmful and that it should be
treated regardless of the underlying cause, which is not supported by clinical data.
🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky
academic.oup.com/ofid/article...
treated regardless of the underlying cause, which is not supported by clinical data.
🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky
academic.oup.com/ofid/article...
October 1, 2025 at 7:35 PM
There is still a widespread belief that fever is harmful and that it should be
treated regardless of the underlying cause, which is not supported by clinical data.
🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky
academic.oup.com/ofid/article...
treated regardless of the underlying cause, which is not supported by clinical data.
🆕💫 Review: Fever in sepsis revisited: Is a little heat what we need? #idsky
academic.oup.com/ofid/article...
Hypervirulent Klebsiella pneumoniae
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
September 25, 2025 at 7:06 PM
Hypervirulent Klebsiella pneumoniae
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
(hvKP ) is a life-threatening pathogen that requires prompt clinical recognition!
🆕💫Tips for intinsvists: Hypervirulent Klebsiella pneumoniae
Delays kill eyes - and sometimes patients! #IDsky #EMIMCC
link.springer.com/article/10.1...
Cryptococcus neoformans and C. gattii represent encapsulated yeasts which have become increasingly common CNS pathogens during the enlarging age of the immunocompromised host
🆕💫 Review: Pain is in the Brain with the Sugar-Coated Killer #idsky
academic.oup.com/jid/article/...
🆕💫 Review: Pain is in the Brain with the Sugar-Coated Killer #idsky
academic.oup.com/jid/article/...
September 24, 2025 at 11:23 PM
Cryptococcus neoformans and C. gattii represent encapsulated yeasts which have become increasingly common CNS pathogens during the enlarging age of the immunocompromised host
🆕💫 Review: Pain is in the Brain with the Sugar-Coated Killer #idsky
academic.oup.com/jid/article/...
🆕💫 Review: Pain is in the Brain with the Sugar-Coated Killer #idsky
academic.oup.com/jid/article/...
🆕🔥State of art review with many🌟s
+ Prof. Jason Roberts
Antibiotic therapy for severe bacterial infections
🟢When to start and not to start antibiotics?
🟢Mon vs combo Abx
🟢PK/PD principles
🟢Drug–drug inx
A #mustread article for ID professional #idsky
link.springer.com/article/10.1...
+ Prof. Jason Roberts
Antibiotic therapy for severe bacterial infections
🟢When to start and not to start antibiotics?
🟢Mon vs combo Abx
🟢PK/PD principles
🟢Drug–drug inx
A #mustread article for ID professional #idsky
link.springer.com/article/10.1...
September 2, 2025 at 2:03 PM
🆕🔥State of art review with many🌟s
+ Prof. Jason Roberts
Antibiotic therapy for severe bacterial infections
🟢When to start and not to start antibiotics?
🟢Mon vs combo Abx
🟢PK/PD principles
🟢Drug–drug inx
A #mustread article for ID professional #idsky
link.springer.com/article/10.1...
+ Prof. Jason Roberts
Antibiotic therapy for severe bacterial infections
🟢When to start and not to start antibiotics?
🟢Mon vs combo Abx
🟢PK/PD principles
🟢Drug–drug inx
A #mustread article for ID professional #idsky
link.springer.com/article/10.1...
Recent years have seen a dramatic rise in carbapenem-resistant K. pneumoniae which is now recognized as one of the most formidable MDR pathogens worldwide.
🆕🔥The mechanisms of antibiotic resistance & drug resistance transmission of Klebsiella pneumoniae #idsky
www.nature.com/articles/s41...
🆕🔥The mechanisms of antibiotic resistance & drug resistance transmission of Klebsiella pneumoniae #idsky
www.nature.com/articles/s41...
August 29, 2025 at 5:39 PM
Recent years have seen a dramatic rise in carbapenem-resistant K. pneumoniae which is now recognized as one of the most formidable MDR pathogens worldwide.
🆕🔥The mechanisms of antibiotic resistance & drug resistance transmission of Klebsiella pneumoniae #idsky
www.nature.com/articles/s41...
🆕🔥The mechanisms of antibiotic resistance & drug resistance transmission of Klebsiella pneumoniae #idsky
www.nature.com/articles/s41...
🆕🔥Streptococcal endocarditis: a meta-analysis of species dependant risk by 🌟s @drtoddlee.bsky.social
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
August 25, 2025 at 4:18 PM
🆕🔥Streptococcal endocarditis: a meta-analysis of species dependant risk by 🌟s @drtoddlee.bsky.social
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
🌟Updated figure 🌟Infective endocarditis prevalence of streptococcal species vs. proportion of streptococcal species bacteraemia #idsky #EMIMCC
www.sciencedirect.com/science/arti...
🆕🔥Prospective,multinational PK study by 🌟 Prof. Roberts
Meropenem & pip/tazo optimised dosing regimens for critically ill patients receiving RRT
Dosing nomograms developed to inform dosing for different RRT settings, urine outputs & target conc #idsky
link.springer.com/article/10.1...
Meropenem & pip/tazo optimised dosing regimens for critically ill patients receiving RRT
Dosing nomograms developed to inform dosing for different RRT settings, urine outputs & target conc #idsky
link.springer.com/article/10.1...
August 14, 2025 at 5:45 PM
🆕🔥Prospective,multinational PK study by 🌟 Prof. Roberts
Meropenem & pip/tazo optimised dosing regimens for critically ill patients receiving RRT
Dosing nomograms developed to inform dosing for different RRT settings, urine outputs & target conc #idsky
link.springer.com/article/10.1...
Meropenem & pip/tazo optimised dosing regimens for critically ill patients receiving RRT
Dosing nomograms developed to inform dosing for different RRT settings, urine outputs & target conc #idsky
link.springer.com/article/10.1...
Finally published
🆕🔥DOTS RCT
Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 #idsky
jamanetwork.com/journals/jam...
🆕🔥DOTS RCT
Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 #idsky
jamanetwork.com/journals/jam...
August 13, 2025 at 3:07 PM
Finally published
🆕🔥DOTS RCT
Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 #idsky
jamanetwork.com/journals/jam...
🆕🔥DOTS RCT
Among participants with complicated S aureus bacteremia who achieved blood culture clearance, dalbavancin was not superior to standard therapy for achieving a more desirable outcome at day 70 #idsky
jamanetwork.com/journals/jam...
July 20, 2025 at 6:55 AM
🔥Finally published🔥
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...
July 17, 2025 at 8:35 PM
🔥Finally published🔥
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...
IDSA Guidelines on the Treatment and Management of Complicated Urinary Tract Infections (cUTI)
#idsky
www.idsociety.org/practice-gui...
How much evidence is needed to revise established clinical practices? and, can data alone truly catalyze such shifts?
Our 🆕🔥 Article at @cidjournal.bsky.social with 🌟s @bradspellberg.bsky.social
Practicing With Intent: How to Teach an Old Dogma New Tricks #IDSky
academic.oup.com/cid/article/...
Our 🆕🔥 Article at @cidjournal.bsky.social with 🌟s @bradspellberg.bsky.social
Practicing With Intent: How to Teach an Old Dogma New Tricks #IDSky
academic.oup.com/cid/article/...
June 24, 2025 at 1:12 PM
How much evidence is needed to revise established clinical practices? and, can data alone truly catalyze such shifts?
Our 🆕🔥 Article at @cidjournal.bsky.social with 🌟s @bradspellberg.bsky.social
Practicing With Intent: How to Teach an Old Dogma New Tricks #IDSky
academic.oup.com/cid/article/...
Our 🆕🔥 Article at @cidjournal.bsky.social with 🌟s @bradspellberg.bsky.social
Practicing With Intent: How to Teach an Old Dogma New Tricks #IDSky
academic.oup.com/cid/article/...
🆕💫 Narrative review in ICM
How to approach a patient hospitalized for pneumonia who is not responding to treatment? #idsky #EMIMCC
link.springer.com/article/10.1...
How to approach a patient hospitalized for pneumonia who is not responding to treatment? #idsky #EMIMCC
link.springer.com/article/10.1...
May 24, 2025 at 8:08 PM
🆕💫 Narrative review in ICM
How to approach a patient hospitalized for pneumonia who is not responding to treatment? #idsky #EMIMCC
link.springer.com/article/10.1...
How to approach a patient hospitalized for pneumonia who is not responding to treatment? #idsky #EMIMCC
link.springer.com/article/10.1...
Words matter.
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
May 21, 2025 at 2:48 PM
Words matter.
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
It’s time to retire the term oral “step-down.”
It implies inferiority of the oral route—and doesn’t align with stewardship principles.
Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship.
What terms do you use—and why? #idsky
What’s the optimal cefazolin dose for MSSA CNS infections?
New PK/PD data says: it’s not just about higher doses—MIC matters.
2g q6h works only if MIC <=0.5 mg/L
For MIC:1-2 mg/L, continuous infusion (10–12g/day) may be needed to hit PD targets #idsky
journals.asm.org/doi/10.1128/...
New PK/PD data says: it’s not just about higher doses—MIC matters.
2g q6h works only if MIC <=0.5 mg/L
For MIC:1-2 mg/L, continuous infusion (10–12g/day) may be needed to hit PD targets #idsky
journals.asm.org/doi/10.1128/...
May 20, 2025 at 4:19 PM
What’s the optimal cefazolin dose for MSSA CNS infections?
New PK/PD data says: it’s not just about higher doses—MIC matters.
2g q6h works only if MIC <=0.5 mg/L
For MIC:1-2 mg/L, continuous infusion (10–12g/day) may be needed to hit PD targets #idsky
journals.asm.org/doi/10.1128/...
New PK/PD data says: it’s not just about higher doses—MIC matters.
2g q6h works only if MIC <=0.5 mg/L
For MIC:1-2 mg/L, continuous infusion (10–12g/day) may be needed to hit PD targets #idsky
journals.asm.org/doi/10.1128/...
🆕🔥Systematic review and consensus guidelines for dose adjustments with many 🌟 Prof. Jason Roberts & Prof Manjunath P Pai
The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC
www.thelancet.com/journals/lan...
The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC
www.thelancet.com/journals/lan...
May 16, 2025 at 2:48 AM
🆕🔥Systematic review and consensus guidelines for dose adjustments with many 🌟 Prof. Jason Roberts & Prof Manjunath P Pai
The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC
www.thelancet.com/journals/lan...
The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC
www.thelancet.com/journals/lan...