Marco P Abrate
abrate.bsky.social
Marco P Abrate
@abrate.bsky.social
PhD in Neuroscience and AI at University College London
Pinned
What drives the sequential emergence of spatial neurons in developing rats? In our ICLR 2026 paper, we show how changes in movement statistics drive spatial tuning. Our model replicates experimental timelines and predicts novel conjunctive tuning maturation.
doi.org/10.64898/2025.12.30.696864
What drives the sequential emergence of spatial neurons in developing rats? In our ICLR 2026 paper, we show how changes in movement statistics drive spatial tuning. Our model replicates experimental timelines and predicts novel conjunctive tuning maturation.
doi.org/10.64898/2025.12.30.696864
February 3, 2026 at 11:04 AM
Reposted by Marco P Abrate
Excited to share that our preprint is out!
doi.org/10.1101/2024...

The structure of place cell reactivations was disordered in AD mice compared to WT! This was predictive of reduced place cell stability and memory performance on a radial-arm maze task.

Here are a few details:

1/5🧵
Disordered Hippocampal Reactivations Predict Spatial Memory Deficits in a Mouse Model of Alzheimer's Disease
Alzheimer's disease (AD) is characterised by progressive memory decline associated with hippocampal degeneration. However, the specific physiological mechanisms underlying hippocampal dysfunction in A...
doi.org
November 28, 2024 at 12:20 PM