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3dsig.bsky.social
3DSIG
@3dsig.bsky.social
130 followers 24 following 33 posts
💻 We are the Structural Bioinformatics and Computational Biology track of the International Society for Computational Biology (ISCB)
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Reposted by 3DSIG
pdbeurope.bsky.social
Structural bioinformaticians are exchanging ideas in Liverpool at #ISMBECCB2025.

🗣️ Wondering what they are talking about?

...chromatin modeling...
📖 pubmed.ncbi.nlm.nih.gov/40236036/
💻 github.com/SFGLab/Repli...

Thanks @3dsig.bsky.social for sharing!
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
The penultimate presentation of the day, with Sevastianos Korsak:"Chromatin as a Coevolutionary Graph: Modeling the Interplay of Replication with Chromatin Dynamics". @iscb.bsky.social #ISMB_ECCB2025 #3DSIG
July 23, 2025 at 9:17 AM
3dsig.bsky.social
Thanks a lot for your presence Prof. Adrian. #ISMB_ECCB2025 #3DSIG
adrianmulholla1.bsky.social Adrian Mulholland @adrianmulholla1.bsky.social · Jul 23
Great to speak in excellent #3DSIG meeting at #ISMBECCB2025 on physics-based simulations in the Age of AlphaFold
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
Please welcome to our Second Keynote Speaker, Prof. Adrian Mulholland - University of Bristol: "Simulations in the age of AlphaFold: dynamics, drug resistance and enzyme design". #3DSIG #ISMBECCB2025 @iscb.bsky.social @adrianmulholla1.bsky.social
July 23, 2025 at 12:07 PM
Reposted by 3DSIG
pdbeurope.bsky.social
PDBe is at #ISMBECCB2025!

Structural Bioinformaticians & Computational Biologist sharing insight & inc. research on:

...predicting protein thermostability change upon mutation...
📖 OrgNet: pubmed.ncbi.nlm.nih.gov/40662839/

Conference Abstracts:
🔗 www.iscb.org/ismbeccb2025...

@iscb.bsky.social
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
The third oral presentation in #3DSIG with Petr Popov: "OrgNet: Orientation-gnostic protein stability assessment using convolutional neural networks." #ISMBECCB2025 @iscb.bsky.social

Following this presentation, we'll break for lunch 🍲 and return shortly after.
July 22, 2025 at 1:28 PM
Reposted by 3DSIG
pdbeurope.bsky.social
Structural bioinformaticians are exchanging ideas in Liverpool at #ISMBECCB2025 (@iscb.bsky.social).

🗣️ Wondering what they are talking about?

Conference Abstracts:
🔗 www.iscb.org/ismbeccb2025...

Thanks @3dsig.bsky.social for sharing!
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
Fourth oral presentation with Ali Baran: "FlowProt: Classifier-Guided Flow Matching for Targeted Protein Backbone Generation in the de novo DNA Methyltransfarase Family" #3DSIG #ISMBECCB2025 @iscb.bsky.social
July 22, 2025 at 1:36 PM
Reposted by 3DSIG
pdbeurope.bsky.social
PDBe is at #ISMBECCB2025!

Structural Bioinformaticians & Computational Biologist sharing insight & inc. research on:

...structure-based drug design...
📖 DrugHive: pubmed.ncbi.nlm.nih.gov/38187658/
💻 github.com/jssweller/Dr...

Thanks @3dsig.bsky.social #3DSIG for sharing!
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
Fifth oral presentation with Dr. Remo Rohs: "Molecular design and structurebased modeling with generative deep learning" #3DSIG #ISMBECCB2025 @iscb.bsky.social
July 22, 2025 at 1:44 PM
Reposted by 3DSIG
pdbeurope.bsky.social
PDBe is at #ISMBECCB2025!

Structural Bioinformaticians & Computational Biologist sharing insight & inc. research on:

...protein complexes...
📖 AlphaPulldown2: pubmed.ncbi.nlm.nih.gov/40088942/
💻 github.com/KosinskiLab/...

Thanks @3dsig.bsky.social #3DSIG for sharing!
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
After break time. Sixth oral presentation of the day. Dmitry Molodenskiy: AlphaPulldown2—a general pipeline for high-throughput structural modeling. @iscb.bsky.social

#ISMB_ECCB2025 #3DSIG
July 22, 2025 at 1:57 PM
3dsig.bsky.social
Throughout the day, we've had amazing oral presentations. Here are some highlights! Our track has an intense second day, full of high-quality science and inspiring research.
@iscb.bsky.social
#ISMB_ECCB2025 #3DSIG @gonzaparra.bsky.social
July 22, 2025 at 1:31 PM
3dsig.bsky.social
We’ve kicked off the second and final day of the #3DSIG track with the third keynote speaker Dr. Diego Ulises Ferreiro: "A (bio)computational perspective on protein folding, function and evolution." @gonzaparra.bsky.social @diegulise.bsky.social #3DSIG #ISMB_ECCB2025 @iscb.bsky.social
July 22, 2025 at 1:22 PM
3dsig.bsky.social
And the last oral presentation of this first day with Clément Bernard: "RNA-TorsionBERT: leveraging language models for RNA 3D torsion angles prediction".
@iscb.bsky.social
#ISMB_ECCB2025 #3DSIG
July 21, 2025 at 4:55 PM
3dsig.bsky.social
The penultimate presentation of the day, with Sevastianos Korsak:"Chromatin as a Coevolutionary Graph: Modeling the Interplay of Replication with Chromatin Dynamics". @iscb.bsky.social #ISMB_ECCB2025 #3DSIG
July 21, 2025 at 4:53 PM
3dsig.bsky.social
We are approaching the end of today’s session. This is the ninth presentation of the day.
"From GWAS to Protein Structures: Illuminating Stress Resistance in Plants" by Su Datt Lam. @iscb.bsky.social
#ISMB_ECCB2025 #3DSIG
July 21, 2025 at 4:50 PM
3dsig.bsky.social
The eighth oral presentation of today is with Justas Dapkunas with: "PPI3D clusters: non-redundant datasets of protein-protein, protein-peptide and proteinnucleic acid complexes, interaction interfaces and binding sites" @iscb.bsky.social

#ISMB_ECCB2025 #3DSIG
July 21, 2025 at 4:48 PM
3dsig.bsky.social
The seventh oral presentation of today with Michel van Kempen: "Extending 3Di: Increasing Protein Structure Search Sensitivity with a Complementary Alphabet" @iscb.bsky.social #ISMB_ECCB2025 #3DSIG
July 21, 2025 at 4:41 PM
3dsig.bsky.social
After break time. Sixth oral presentation of the day. Dmitry Molodenskiy: AlphaPulldown2—a general pipeline for high-throughput structural modeling. @iscb.bsky.social

#ISMB_ECCB2025 #3DSIG
July 21, 2025 at 4:39 PM
3dsig.bsky.social
Thanks for sharing the event!
pdbeurope.bsky.social Protein Data Bank in Europe (PDBe) @pdbeurope.bsky.social · Jul 21
Structural bioinformaticians are exchanging ideas in Liverpool at #ISMB_ECCB2025.

Wondering what they are talking about?

Presenting on:
3dsig.bsky.social 3DSIG @3dsig.bsky.social · Jul 21
The second oral presentation in #3DSIG with Zhidian Zhang: "Probing Homo-Oligomeric Interaction Signals in Protein Language Models" @iscb.bsky.social #ISMBECCB2025
July 21, 2025 at 4:09 PM
3dsig.bsky.social
Fifth oral presentation with Dr. Remo Rohs: "Molecular design and structurebased modeling with generative deep learning" #3DSIG #ISMBECCB2025 @iscb.bsky.social
July 21, 2025 at 2:32 PM
3dsig.bsky.social
Fourth oral presentation with Ali Baran: "FlowProt: Classifier-Guided Flow Matching for Targeted Protein Backbone Generation in the de novo DNA Methyltransfarase Family" #3DSIG #ISMBECCB2025 @iscb.bsky.social
July 21, 2025 at 1:47 PM
3dsig.bsky.social
Please welcome to our Second Keynote Speaker, Prof. Adrian Mulholland - University of Bristol: "Simulations in the age of AlphaFold: dynamics, drug resistance and enzyme design". #3DSIG #ISMBECCB2025 @iscb.bsky.social @adrianmulholla1.bsky.social
July 21, 2025 at 1:37 PM
3dsig.bsky.social
The third oral presentation in #3DSIG with Petr Popov: "OrgNet: Orientation-gnostic protein stability assessment using convolutional neural networks." #ISMBECCB2025 @iscb.bsky.social

Following this presentation, we'll break for lunch 🍲 and return shortly after.
July 21, 2025 at 11:52 AM
3dsig.bsky.social
The second oral presentation in #3DSIG with Zhidian Zhang: "Probing Homo-Oligomeric Interaction Signals in Protein Language Models" @iscb.bsky.social #ISMBECCB2025
July 21, 2025 at 11:48 AM
3dsig.bsky.social
The first oral presentation in #3DSIG with Meghan Kshirsagar: "Rapid and accurate prediction of protein homo-oligomer symmetry using Seq2Symm" @iscb.bsky.social #ISMBECCB2025
July 21, 2025 at 11:46 AM
3dsig.bsky.social
Please welcome to our first Keynote Speaker Dr Franca Fraternali - University College London. #3DSIG #ISMBECCB2025 @iscb.bsky.social #ISCB
July 21, 2025 at 11:38 AM
3dsig.bsky.social
#3DSIG in ISMB/ECCB 2025 have started!
We see in the ROOM 03B. We are very excited to welcome you.
#ISMBECCB2025 #ISCB @iscb.bsky.social
July 21, 2025 at 11:09 AM
3dsig.bsky.social
We’re thrilled to have you as Chair of our track, Gonza! 🙌 Your leadership and vision are a huge part of what makes this event so exciting. Let’s make #ISMB2025 unforgettable! 💥🧬
gonzaparra.bsky.social Gonzalo Parra @gonzaparra.bsky.social · Jul 11
1 week away to go to Liverpool to one more
@iscb.bsky.social #ISMB2025! It's my favourite event of the year!

Happy to chair @3dsig.bsky.social and the #LGBTQIA+ meet up!

Looking forward to meet all the friends and colleagues! Let's organisé for coffees & dinners! ⭐️🎶🤝
July 15, 2025 at 7:59 PM
3dsig.bsky.social
#CountdownToISMB

🚨 We’re just DAYS AWAY from the start of #ISMB2025 – the world’s biggest bioinformatics event! 🌍🧬

We’re thrilled to remind you of our THREE incredible CHAIRS for #3DSIG track. Three world-class researchers leading the way in science! 💥

#ISMB2025 #Bioinformatics #ISCB #ISMB 🧪👩‍💻👨‍💻
July 15, 2025 at 7:58 PM