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If you're an ISTAART member, please consider voting for me as one of your incoming Steering Committee members for the Neuroimaging PIA! I'd love the opportunity to be part of this exciting community of scientists and shape the future of translational neuroimaging.

The plan for NIH is in, source with full 64 page proposal for all of HHS is linked. Reported in WaPo. This is catastrophic. Reduction to 8 centers. 40% cut in budget. 15% IDC cap. This will decimate science across America open.substack.com/pub/insideme...

One of the country's leading Alzheimer's projects is in jeopardy

A pause to NIH funding has researchers scrambling for contingency plans at the University of Washington’s Alzheimer’s Disease Research Center

@evanbush.bsky.social reports at @nbcnews.com

www.nbcnews.com/health/healt...

🧵Yesterday, I received notice that my #NIH grant, on the social environment, lifecourse, epigenetics & #birthoutcomes in Black families, was terminated. This grant represented a critical effort to address the ⬆️ rates of maternal & infant mortality in the US, particularly among Black mothers & babies

NBC News: A federal judge just issued a final judgement and permanent injunction against the Trump admin — ruling that the National Institutes of Health must continue funding research grants at their original, full amounts.  @msnbc.com

Temporary restraining order issued last night for the public health-related lawsuit against HHS on Tuesday)

www.nytimes.com/2025/04/03/u...

This is fantastic, Roberto, not sure why we hadn’t run into your work… we’ll check this out and most definitely follow up with you!

Ah we’ve totally missed this! Thank you for pointing me to it!!☺️

If you're at #CNS2025, be sure to check out the poster presentation Monday morning (D139) by our wonderful mentee Josh on flatsurfer -- our soon-to-be-released python package to create limbic-centered flat maps of the cerebral cortex. w/ @jtheriault.bsky.social

Yes, taking 30+ short MPRAGE scans as was done here wouldn't be feasible in a typical neuroimaging experiment (and hence PoC!). We're hopeful that compressed sensing sequences with faster (~1 min) AT will prove more useful and realistic in longitudinal studies over short time intervals.

**New Preprint** We show that pooling morphometric estimates via "cluster scanning" (i.e., repeat T1w MPRAGE scans with AT = ~2 min/ea.) allows detection of cortical atrophy in phenotypically vulnerable regions in phenotypes of AD and FTLD over 3- and 6-months.

www.medrxiv.org/content/10.1...

Now published in Brain! Check out the paper here: academic.oup.com/brain/advanc...

***New preprint!*** We show that 18F-Flortaucipir PET signal within the canonical DMN is a relatively specific and strong predictor of clinical decline in early symptomatic patients with atypical AD clinical syndromes.