Ying Ge
@yingge2121.bsky.social
190 followers
82 following
45 posts
Professor of Cell & Regenerative Biology and Chemistry at UW-Madison, Director of Human Proteomics Program🌱 | Passionate about Top-Down Proteomics, Cardiac Systems Biology, and Precision Medicine 🔬 | Optimist who loves gardening 🌸 Views are my own.
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Ying Ge
@yingge2121.bsky.social
· Sep 13
A Single-Step Protein Extraction for Lung Extracellular Matrix Proteomics Enabled by the Photocleavable Surfactant Azo and timsTOF Pro
In BriefWe developed a single-step extraction method for extracellular matrix (ECM)
proteomics using the photocleavable surfactant Azo, significantly improving throughput
and reproducibility. This app...
www.mcponline.org
Ying Ge
@yingge2121.bsky.social
· Sep 13
High-Sensitivity Top-Down Proteomics Reveals Enhanced Maturation of Micropatterned Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are increasingly used for disease modeling, drug discovery, and precision medicine, yet their utility is often limited by their i...
pubs.acs.org
Ying Ge
@yingge2121.bsky.social
· Aug 16
Structural Heterogeneity of Proteoform-Ligand Complexes in Adenosine Monophosphate-Activated Protein Kinase Uncovered by Integrated Top-Down Mass Spectrometry
Adenosine monophosphate-activated protein kinase (AMPK) is a heterotrimeric complex (αβγ) that serves as a master regulator of cellular metabolism, making it a prominent drug target for various diseas...
pubs.acs.org
Reposted by Ying Ge
Reposted by Ying Ge
Reposted by Ying Ge
Joe Loo
@joelooucla.bsky.social
· Jun 9
Ying Ge
@yingge2121.bsky.social
· Jun 2
Reposted by Ying Ge