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wredenberglab.bsky.social
WredenbergLab
@wredenberglab.bsky.social
290 followers 39 following 7 posts
Mitochondrial research at the Division for Molecular Metabolism, Karolinska Institute wredenberglab.com
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wredenberglab.bsky.social
Excited to share our latest work on how mitochondrial methylation shapes gene expression. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis.
Thanks to everyone invovled. @ruthicglasgow.bsky.social @amunts.bsky.social
🔗 rdcu.be/etk12
The mitochondrial methylation potential gates mitoribosome assembly
Nature Communications - Here, using long-read RNA sequencing, SILAC proteomics, and cryo-EM, the authors show that loss of mitochondrial methylation impairs rRNA processing and ribosome maturation,...
rdcu.be
June 25, 2025 at 2:16 PM
Reposted by WredenbergLab
paulinawanrooij.bsky.social
Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share!
www.umu.se/en/work-with...
Postdoctoral fellowship (2 years) to study mitochondrial DNA stability
www.umu.se
April 16, 2025 at 11:43 AM
Reposted by WredenbergLab
haukehillen.bsky.social
Happy to share out latest collaborative work with the groups of Ricarda Richter-Dennerlein and Peter Rehling just out in
@natcomms.nature.com. Great work led by two very talented PhD students - Franziska Finke (our lab) and Marleen Heinrichs (Richter-Dennerlein lab).
www.nature.com/articles/s41...
Coupling of ribosome biogenesis and translation initiation in human mitochondria - Nature Communications
Mitochondrial ribosome biogenesis requires the assistance of multiple assembly factors. Here, the authors provide insights into the essential role of the GTPase MTG3 during small subunit biogenesis an...
www.nature.com
April 17, 2025 at 9:39 AM
Reposted by WredenbergLab
mito-at-gu.bsky.social
New paper out from the Falkenberg and Gustafsson labs. Thanks to Pretzel for a successful collaboration.
www.nature.com/articles/s41...
Small molecules restore mutant mitochondrial DNA polymerase activity - Nature
An activator of DNA polymerase γ restores function to disease-causing mutant variants and demonstrates a potential route to treatments for inherited mitochondrial disorders involving POLG mutations.
www.nature.com
April 9, 2025 at 4:30 PM
wredenberglab.bsky.social
Interested in mitochondrial biology? We are looking for an enthusiastic PostDoctoral fellow and PhD student to join our group in Stockholm.
For the PhD position: kidoktorand.varbi.com/what:job/job...
For the PostDoc position: ki.varbi.com/what:job/job...
Doktorandplats inom mitokondriell metabolism
Vill du bidra till medicinsk forskning av toppkvalitet? Att vara doktorand innebär att vara antagen till en utbildning på forskarnivå (forskarutbildning) där man följer en individuell studieplan.
kidoktorand.varbi.com
March 11, 2025 at 3:37 PM
wredenberglab.bsky.social
We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. @naturecomms.bsky.social
www.nature.com/articles/s41...
Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster - Nature Communications
Finding ways to compensate for mitochondrial dysfunction is essential. Here, the authors performed a genome-wide genetic screen to identify genes that mitigate the larvae lethal phenotype of a fruit f...
www.nature.com
December 23, 2024 at 4:18 PM
wredenberglab.bsky.social
We are hiring. Looking for a PostDoc in mitochondrial biology? We are offering an excellent scientific environment at the Division of Molecular Metabolism. Apply here:
ki.varbi.com/ny/what:job/...
1-2 Postdoctoral researchers in mitochondrial biology (scholarship)
Do you want to contribute to improving human health? Research at the Division of Molecular Metabolism aims to understand the regulation of mitochondrial function and the role of mitochondrial dysfunct
ki.varbi.com
December 14, 2024 at 1:54 PM