Velindre Library
@vcclibrary.bsky.social
Velindre University NHS Trust Library, the only cancer specialist library service in Wales. Supporting NHS and academic staff, students and health professionals.
Best audio accompaniment for putting up Christmas decs? Obviously, it's the new Immunobuddies! Episode 171: Clinical Application of the Microbiome with International Expert Professor Monty Pal City of Hope California. @velindrecc.bsky.social @rickyfrazer1.bsky.social open.spotify.com/episode/1QtM...
Episode 171: Clinical Application of the Microbiome with International Expert Professor Monty Pal City of Hope California
open.spotify.com
December 5, 2025 at 9:58 AM
Best audio accompaniment for putting up Christmas decs? Obviously, it's the new Immunobuddies! Episode 171: Clinical Application of the Microbiome with International Expert Professor Monty Pal City of Hope California. @velindrecc.bsky.social @rickyfrazer1.bsky.social open.spotify.com/episode/1QtM...
Radiotherapy for Oesophageal #Cancer in the United Kingdom: Patterns of Practice and Quality Indicators @velindrecc.bsky.social www.sciencedirect.com/science/arti...
Radiotherapy for Oesophageal Cancer in the United Kingdom: Patterns of Practice and Quality Indicators
There is limited guidance relating to the provision of radiotherapy for patients with oesophageal cancer. Given this, we sought to assess variation in…
www.sciencedirect.com
December 4, 2025 at 2:27 PM
Radiotherapy for Oesophageal #Cancer in the United Kingdom: Patterns of Practice and Quality Indicators @velindrecc.bsky.social www.sciencedirect.com/science/arti...
CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence for regulatory science and innovation in pharmacogenomics (CERSI-PGx). @velindrecc.bsky.social bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
BPS Publications
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and per...
bpspubs.onlinelibrary.wiley.com
December 4, 2025 at 2:23 PM
CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence for regulatory science and innovation in pharmacogenomics (CERSI-PGx). @velindrecc.bsky.social bpspubs.onlinelibrary.wiley.com/doi/10.1002/...
Glofitamab with gemcitabine and oxaliplatin for treating relapsed or refractory diffuse large B-cell lymphoma. www.nice.org.uk/guidance/ta1...
Overview | Glofitamab with gemcitabine and oxaliplatin for treating relapsed or refractory diffuse large B-cell lymphoma | Guidance | NICE
www.nice.org.uk
December 4, 2025 at 2:14 PM
Glofitamab with gemcitabine and oxaliplatin for treating relapsed or refractory diffuse large B-cell lymphoma. www.nice.org.uk/guidance/ta1...
NICE [Technology Appraisal Guideline]: Talquetamab for treating relapsed and refractory multiple myeloma after 3 or more treatments. www.nice.org.uk/guidance/ta1...
Overview | Talquetamab for treating relapsed and refractory multiple myeloma after 3 or more treatments | Guidance | NICE
www.nice.org.uk
December 4, 2025 at 2:12 PM
NICE [Technology Appraisal Guideline]: Talquetamab for treating relapsed and refractory multiple myeloma after 3 or more treatments. www.nice.org.uk/guidance/ta1...
The use of tramadol for cancer-associated pain—a systematic review. link.springer.com/article/10.1...
The use of tramadol for cancer-associated pain—a systematic review - Supportive Care in Cancer
Background Tramadol has been used for cancer pain and reported in the literature with varying relative effects compared to other analgesics. To our knowledge, there is no comprehensive systematic revi...
link.springer.com
December 4, 2025 at 2:10 PM
The use of tramadol for cancer-associated pain—a systematic review. link.springer.com/article/10.1...
I want to get better; I don’t want to just stay at home: a theory-driven qualitative exploration of participation in a home-based #LungCancer exercise clinical trial. link.springer.com/article/10.1...
I want to get better; I don’t want to just stay at home: a theory-driven qualitative exploration of participation in a home-based lung cancer exercise clinical trial - Supportive Care in Cancer
Purpose We conducted a multi-site randomised controlled trial (RCT) of home-based exercise and self-management for patients after lung cancer surgery, which improved the intervention group’s exercise ...
link.springer.com
December 4, 2025 at 2:06 PM
I want to get better; I don’t want to just stay at home: a theory-driven qualitative exploration of participation in a home-based #LungCancer exercise clinical trial. link.springer.com/article/10.1...
Noninferiority of One HPV Vaccine Dose to Two Doses. #CervicalCancer www.nejm.org/doi/full/10....
www.nejm.org
December 4, 2025 at 2:02 PM
Noninferiority of One HPV Vaccine Dose to Two Doses. #CervicalCancer www.nejm.org/doi/full/10....
Lorlatinib in Tyrosine Kinase Inhibitor−Naive Advanced ROS1-Positive Non−Small Cell #LungCancer: A Phase 2 Nonrandomized Clinical Trial. jamanetwork.com/journals/jam...
Lorlatinib in Tyrosine Kinase Inhibitor−Naive Advanced ROS1-Positive Non−Small Cell Lung Cancer
This multicenter nonrandomized clinical trial evaluates the efficacy and safety of lorlatinib for patients with advanced ROS1-positive non−small cell lung cancer who have not been treated with a tyros...
jamanetwork.com
December 4, 2025 at 1:53 PM
Lorlatinib in Tyrosine Kinase Inhibitor−Naive Advanced ROS1-Positive Non−Small Cell #LungCancer: A Phase 2 Nonrandomized Clinical Trial. jamanetwork.com/journals/jam...
Person-centred approach for people with learning disabilities in palliative care: the challenges. spcare.bmj.com/content/earl...
Person-centred approach for people with learning disabilities in palliative care: the challenges
Background People with a learning disability (PWLD) are living longer with a greater need for palliative care. Research has identified that people with a learning disability experience challenges when...
spcare.bmj.com
December 4, 2025 at 1:47 PM
Person-centred approach for people with learning disabilities in palliative care: the challenges. spcare.bmj.com/content/earl...
STELLAR: Phase III, Randomized, Open-Label Study of Eflornithine Plus Lomustine Versus Lomustine Alone in Patients With Recurrent Grade 3 Astrocytoma. ascopubs.org/doi/10.1200/...
ASCO Publications
ascopubs.org
December 4, 2025 at 12:53 PM
STELLAR: Phase III, Randomized, Open-Label Study of Eflornithine Plus Lomustine Versus Lomustine Alone in Patients With Recurrent Grade 3 Astrocytoma. ascopubs.org/doi/10.1200/...
Amivantamab Plus Lazertinib in Atypical EGFR-Mutated Advanced Non–Small Cell #LungCancer: Results From CHRYSALIS-2. ascopubs.org/doi/10.1200/...
Amivantamab Plus Lazertinib in Atypical <i>EGFR</i>-Mutated Advanced Non–Small Cell Lung Cancer: Results From CHRYSALIS-2
PURPOSEFor patients with advanced non–small cell lung cancer (NSCLC) harboring atypical epidermal
growth factor receptor (EGFR) mutations (eg, S768I, L861Q, G719X), efficacy of current treatment optio...
ascopubs.org
December 4, 2025 at 12:52 PM
Amivantamab Plus Lazertinib in Atypical EGFR-Mutated Advanced Non–Small Cell #LungCancer: Results From CHRYSALIS-2. ascopubs.org/doi/10.1200/...
Atezolizumab With Bevacizumab and Nonplatinum Chemotherapy for Recurrent #OvarianCancer: Final Results From the Placebo-Controlled AGO-OVAR 2.29/ENGOT-ov34 Phase III Trial. ascopubs.org/doi/10.1200/...
Atezolizumab With Bevacizumab and Nonplatinum Chemotherapy for Recurrent Ovarian Cancer: Final Results From the Placebo-Controlled AGO-OVAR 2.29/ENGOT-ov34 Phase III Trial
PURPOSETo evaluate atezolizumab combined with bevacizumab and non–platinum-based chemotherapy
for recurrent ovarian cancer.METHODSThe double-blind randomized phase III AGO-OVAR 2.29/ENGOT-ov34 trial (...
ascopubs.org
December 4, 2025 at 12:50 PM
Atezolizumab With Bevacizumab and Nonplatinum Chemotherapy for Recurrent #OvarianCancer: Final Results From the Placebo-Controlled AGO-OVAR 2.29/ENGOT-ov34 Phase III Trial. ascopubs.org/doi/10.1200/...
Peri-operative tislelizumab plus neoadjuvant chemotherapy for patients with resectable non-small cell #LungCancer: final analysis of the randomized RATIONALE-315 trial. www.annalsofoncology.org/article/S092...
Peri-operative tislelizumab plus neoadjuvant chemotherapy for patients with resectable non-small cell lung cancer: final analysis of the randomized RATIONALE-315 trial
Peri-operative immunotherapy, particularly anti-programmed cell death protein-1 therapy,
combined with neoadjuvant chemotherapy has emerged as one of the standard-of-care
options for resectable non-sm...
www.annalsofoncology.org
December 4, 2025 at 12:43 PM
Peri-operative tislelizumab plus neoadjuvant chemotherapy for patients with resectable non-small cell #LungCancer: final analysis of the randomized RATIONALE-315 trial. www.annalsofoncology.org/article/S092...
5-Year Outcomes of Moderately Hypofractionated Whole Pelvic Radiotherapy with Concurrent Chemotherapy and Image Guided High Dose Rate Brachytherapy for Locally Advanced Cervical Carcinoma. www.redjournal.org/article/S036...
5-Year Outcomes of Moderately Hypofractionated Whole Pelvic Radiotherapy with Concurrent Chemotherapy and Image Guided High Dose Rate Brachytherapy for Locally Advanced Cervical Carcinoma
Although moderately hypofractionated external beam radiotherapy (H-EBRT) has been
practiced for locally advanced cervical carcinoma (LACC), prospective evidence remains
limited. We evaluated the role ...
www.redjournal.org
December 4, 2025 at 12:40 PM
5-Year Outcomes of Moderately Hypofractionated Whole Pelvic Radiotherapy with Concurrent Chemotherapy and Image Guided High Dose Rate Brachytherapy for Locally Advanced Cervical Carcinoma. www.redjournal.org/article/S036...
Effects of Nutritional Interventions on Quality of Life in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy Based on Dynamic Nutritional Risk Screening and Assessment: An Open-label Single-center Randomized Phase 3 Trial. www.redjournal.org/article/S036...
Effects of Nutritional Interventions on Quality of Life in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy Based on Dynamic Nutritional Risk Screening and Assessment: An Open-label Sing...
: Malnutrition is common among patients with nasopharyngeal carcinoma (NPC) undergoing
radiotherapy and is associated with diminished quality of life (QoL). However, the
impact of individualized nutri...
www.redjournal.org
December 4, 2025 at 12:19 PM
Effects of Nutritional Interventions on Quality of Life in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy Based on Dynamic Nutritional Risk Screening and Assessment: An Open-label Single-center Randomized Phase 3 Trial. www.redjournal.org/article/S036...
ESTRO-ISRS clinical practice recommendations for re-irradiation of spinal mestastases with Stereotactic body radiotherapy: delphi consensus supported by a systematic review and meta-analysis. www.sciencedirect.com/science/arti...
ESTRO-ISRS clinical practice recommendations for re-irradiation of spinal mestastases with Stereotactic body radiotherapy: delphi consensus supported by a systematic review and meta-analysis
Stereotactic body radiotherapy (SBRT) is an established treatment for previously unirradiated spinal metastases; however, the literature is limited wi…
www.sciencedirect.com
December 4, 2025 at 12:15 PM
ESTRO-ISRS clinical practice recommendations for re-irradiation of spinal mestastases with Stereotactic body radiotherapy: delphi consensus supported by a systematic review and meta-analysis. www.sciencedirect.com/science/arti...
Cumulative dose evaluation in clinical reirradiation – Consensus guidance on technical considerations by the ESTRO reirradiation focus group. www.sciencedirect.com/science/arti...
Cumulative dose evaluation in clinical reirradiation – Consensus guidance on technical considerations by the ESTRO reirradiation focus group
Reirradiation is increasingly used, but its safe application requires accurate evaluation of cumulative doses to organs at risk. Methods of cumulative…
www.sciencedirect.com
December 4, 2025 at 12:12 PM
Cumulative dose evaluation in clinical reirradiation – Consensus guidance on technical considerations by the ESTRO reirradiation focus group. www.sciencedirect.com/science/arti...
Clustering of dosimetric profiles reveals distinct local control probabilities after SABR in oligometastatic head and neck #Cancer: insights from the OMET phase II trial quality assurance Process. www.thegreenjournal.com/article/S016...
Clustering of dosimetric profiles reveals distinct local control probabilities after SABR in oligometastatic head and neck cancer: insights from the OMET phase II trial quality assurance Process
Stereotactic ablative radiotherapy (SABR) is increasingly used in the management of oligometastatic disease. However, variability in SABR plans raises…
www.sciencedirect.com
December 4, 2025 at 12:03 PM
Clustering of dosimetric profiles reveals distinct local control probabilities after SABR in oligometastatic head and neck #Cancer: insights from the OMET phase II trial quality assurance Process. www.thegreenjournal.com/article/S016...
The telomerase vaccine UV1 combined with ipilimumab and nivolumab versus ipilimumab and nivolumab in advanced melanoma (INITIUM): a randomized open-label phase 2 study. www.ejcancer.com/article/S095...
The telomerase vaccine UV1 combined with ipilimumab and nivolumab versus ipilimumab and nivolumab in advanced melanoma (INITIUM): a randomized open-label phase 2 study
Immune checkpoint inhibitor (ICI) combinations have improved outcomes in patients
with advanced melanoma; however, long term survival remains poor. The addition of
therapeutic cancer vaccines to ICI c...
www.ejcancer.com
December 4, 2025 at 11:59 AM
The telomerase vaccine UV1 combined with ipilimumab and nivolumab versus ipilimumab and nivolumab in advanced melanoma (INITIUM): a randomized open-label phase 2 study. www.ejcancer.com/article/S095...
Prediction of HER2 Changes post-Neoadjuvant Therapy based on Fusion of Ultrasound Radiomics and Clinicopathological Features Empowered by Explainable AI: a Multicenter Study. www.ejcancer.com/article/S095...
Prediction of HER2 Changes post-Neoadjuvant Therapy based on Fusion of Ultrasound Radiomics and Clinicopathological Features Empowered by Explainable AI: a Multicenter Study
Dynamic HER2 expression changes during neoadjuvant therapy (NAT) challenge precision
oncology. Current biopsy-dependent evaluation inadequately meets clinical needs for
dynamic monitoring. We develope...
www.ejcancer.com
December 4, 2025 at 11:57 AM
Prediction of HER2 Changes post-Neoadjuvant Therapy based on Fusion of Ultrasound Radiomics and Clinicopathological Features Empowered by Explainable AI: a Multicenter Study. www.ejcancer.com/article/S095...
Combination of predicted sensitivity to endocrine therapy (SET2,3 index) and the Recurrence Score® in node-positive #BreastCancer: independent validation in the PACS-01 trial. www.ejcancer.com/article/S095...
Combination of predicted sensitivity to endocrine therapy (SET2,3 index) and the Recurrence Score® in node-positive breast cancer: independent validation in the PACS-01 trial.
To independently confirm whether the combination of sensitivity to endocrine therapy
(SET2,3) index and Recurrence Score® (RS) improves prognostic assessment for patients
with hormone receptor-positiv...
www.ejcancer.com
December 4, 2025 at 11:51 AM
Combination of predicted sensitivity to endocrine therapy (SET2,3 index) and the Recurrence Score® in node-positive #BreastCancer: independent validation in the PACS-01 trial. www.ejcancer.com/article/S095...
Radiotherapy plan quality assurance in the ABC-07 trial of stereotactic body radiotherapy (SBRT) for locally advanced biliary tract #Cancer. www.clinicaloncologyonline.net/article/S093...
Radiotherapy plan quality assurance in the ABC-07 trial of stereotactic body radiotherapy (SBRT) for locally advanced biliary tract cancer
The ABC-07 phase II randomised controlled trial (ISRCTN: 10639376) investigated the
addition of stereotactic body radiotherapy (SBRT) to systemic chemotherapy in locally
advanced biliary tract cancers...
www.clinicaloncologyonline.net
December 4, 2025 at 11:47 AM
Radiotherapy plan quality assurance in the ABC-07 trial of stereotactic body radiotherapy (SBRT) for locally advanced biliary tract #Cancer. www.clinicaloncologyonline.net/article/S093...
Electronic health record-facilitated symptom surveillance and collaborative care intervention in oncology (E2C2): a cluster-randomised, population-level, stepped-wedge, pragmatic trial. www.thelancet.com/journals/lan...
Electronic health record-facilitated symptom surveillance and collaborative care intervention in oncology (E2C2): a cluster-randomised, population-level, stepped-wedge, pragmatic trial
Centralised EHR-facilitated, symptom surveillance and collaborative care management
are more beneficial than symptom surveillance alone in reducing the population burden
of SPPADE symptoms in oncology...
www.thelancet.com
December 4, 2025 at 11:41 AM
Electronic health record-facilitated symptom surveillance and collaborative care intervention in oncology (E2C2): a cluster-randomised, population-level, stepped-wedge, pragmatic trial. www.thelancet.com/journals/lan...
The weekly wait is over - The Immunobuddies are here! Episode 170: New Immunotherapies for Community Teams and Non-Oncologists Final Part with Macmillan GP Lead for Wales Dr Elise Lang. @velindrecc.bsky.social @rickyfrazer1.bsky.social open.spotify.com/episode/0zds...
Episode 170: New Immunotherapies for Community Teams and Non-Oncologists Final Part with Macmillan GP Lead for Wales Dr Elise Lang
open.spotify.com
November 28, 2025 at 12:05 PM
The weekly wait is over - The Immunobuddies are here! Episode 170: New Immunotherapies for Community Teams and Non-Oncologists Final Part with Macmillan GP Lead for Wales Dr Elise Lang. @velindrecc.bsky.social @rickyfrazer1.bsky.social open.spotify.com/episode/0zds...