Toshi Yokota
@tyokota.bsky.social
15 followers 9 following 25 posts
Molecular Geneticist | RNA Therapeutics Innovator | FCAHS Fellow Distinguished Professor, University of Alberta | Advancing RNA-based therapies, genome editing, and precision medicine for neuromuscular and other genetic diseases
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Honoured to be named a University of Alberta Distinguished Professor.
Grateful to my students, collaborators, and colleagues worldwide for their dedication to advancing genetic medicine for rare diseases.
Proud to be part of this inspiring community. www.ualberta.ca/en/the-quad/...
Celebrating the Recipients of the 2025 Faculty Excellence Awards
www.ualberta.ca
📢 New publication from our lab!
“Local Non-Coding Regulatory Elements in Muscular Dystrophies” now out in IJMS.
Exploring how lncRNAs, miRNAs, and epigenetic regulators contribute to muscular dystrophies.
👉 www.mdpi.com/1422-0067/26... Congrats to Harry Wilton-Clark and Sebastian Rodriguez!
www.mdpi.com
🎉 Exciting news! Our preprint “Local Non-Coding Regulatory Elements in the Muscular Dystrophies” (with Harry Wilton-Clark & Sebastian Hernandez Rodriguez) has already reached 100 downloads on @preprints.bsky.social Grateful for the growing interest. www.preprints.org/manuscript/2...
www.preprints.org
Excited to share that our new preprint is now online! 🚀
"Artificial Intelligence-Driven Design of Antisense Oligonucleotides for Precision Medicine in Neuromuscular Disorders" Grateful to my co-authors for their contributions.
👉 www.preprints.org/manuscript/2... www.preprints.org/manuscript/2...
www.preprints.org
Thrilled to share that our MD/PhD student Harry Wilton-Clark won First Place at Falling Walls Lab Edmonton 2025 🏆👏
His talk, Breaking the Wall of Rare Disease Therapies, will now represent Edmonton on the world stage in Berlin! 🌍 #FallingWallsLab #RareDisease www.ualberta.ca/en/graduate-...
Falling Walls Lab Edmonton
www.ualberta.ca
Excited to share our new preprint: Local Non-Coding Regulatory Elements in the Muscular Dystrophies 🚀
We review how #lncRNAs, #miRNAs, and epigenetic regulators shape disease mechanisms in #DMD, #FSHD, #LGMD & more. www.preprints.org/manuscript/2... #preprints via @Preprints_org
www.preprints.org
New hope for Duchenne muscular dystrophy💙
Our team identified DG9, a peptide that boosts delivery of exon-skipping therapy to the heart — a key unmet need in DMD. This approach restored cardiac & skeletal muscle function in mice. www.ualberta.ca/en/medicine/... @wchriuofa.bsky.social
Researchers build on a breakthrough in treating muscular dystrophy
www.ualberta.ca
Excited to share our latest preprint:
"Cardiac Cell and Animal Models for Duchenne Muscular Dystrophy in the Era of Gene Therapy and Precision Medicine"
Now online at @PreprintsOrg!
🧬 www.preprints.org/manuscript/2...
#DMD #GeneTherapy #PrecisionMedicine #Cardiology #Preprint #MuscularDystrophy
www.preprints.org
🎉 New Release! The 2nd Edition of Exon Skipping and Inclusion Therapies is now published with Springer Nature!
This edition highlights new breakthroughs in RNA-targeted therapies.
Grab your copy
link.springer.com/book/10.1007...
#ExonSkipping #RNAtherapeutics #GeneTherapy #DMD #SMA #SpringerNature
Exon Skipping and Inclusion Therapies
This book presents a collection of protocols reflecting the latest advancements in exon skipping and inclusion strategies.
link.springer.com
🚨 New publication alert!

Our latest review on Brogidirsen & exon 44 skipping therapy for Duchenne muscular dystrophy is out in Genes. We discuss advances, challenges, and future directions for RNA-based therapies.

🔗 Read the full open-access article: www.mdpi.com/2073-4425/16...
www.mdpi.com
www.preprints.org/manuscript/2... Excited to share our latest preprint:
🧬 “Brogidirsen and Exon 44 Skipping for DMD: Advances and Challenges in RNA-Based Therapy”
📄 www.preprints.org/manuscript/2...
Proud of Annie Tang’s excellent work leading this review. #DMD #RNAtherapy #exonskipping #ASO
www.preprints.org
🎉 Proud to see our postdoc Dr. Hidenori Moriyama featured by @wchriuofa.bsky.social ! His work on improving ASO delivery for muscular dystrophy is bringing new hope to families. Thank you @stollerykids.bsky.social for supporting this research.
#RareDisease #WCHRI www.wchri.org/our-impact/p...
wchri.org
🚨 Just featured in The Gateway!
Our lab's work on exon skipping & antisense therapy is helping pave the way for genetic treatments that target DMD and beyond. 📰 Read the article: thegatewayonline.ca/2025/05/u-of...
U of A researchers make advancements in gene therapy - The Gateway
U of A professor of medical genetics Toshifumi Yokota and the Yokota Lab are making advancements in gene therapy.
thegatewayonline.ca
🚨 We’re hiring!
The Yokota Lab @ualberta.bsky.social is looking for a Postdoctoral Fellow to join our team developing cutting-edge genetic therapies for muscular dystrophy & rare diseases.
🌍 Edmonton, AB
🧪 3-year term (annual renewal)
Apply by July 31 👉 jrecin.jst.go.jp/seek/SeekJor...
JREC-IN | Postdoctoral Fellow (Yokota Lab)
イノベーション創出を担う研究人材のためのキャリア支援ポータルサイト
jrecin.jst.go.jp
Honored to receive a 2025 grant from Muscular Dystrophy Canada to advance lipid nanoparticle–based therapies for Friedreich ataxia and SBMA, with a focus on supporting Indigenous communities affected by neuromuscular disorders.
#FA #SBMA #GeneTherapy #IndigenousHealth muscle.ca/researchers/...
Translational Science and Clinical Research Grants – Muscular Dystrophy Canada
muscle.ca
Proud to have hosted Fulbright Scholar Omar Sheikh in the Yokota Lab! As a scientist living with Becker MD, his work on genetic therapies and advocacy for inclusion in science made a lasting impact. Read about his journey. #Fulbright #MuscularDystrophy #InclusionInSTEM miusa.org/resource/per...
From Lab to Life: Omar Sheikh's Canadian Fulbright Adventure - MIUSA
Omar Shake learned about life and his disability on a Fulbright research grant in Canada.
miusa.org
🚀 Exciting news! Our team has been awarded a $1.3M CIHR grant to study Spinal-Bulbar Muscular Atrophy (SBMA) in Indigenous communities of the Prairie Provinces. Honored to collaborate with an incredible team of researchers & community leaders! @nmd4c.ca neuromuscularnetwork.ca/news/cihr-fu...