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transplantation.bsky.social @transplantation.bsky.social · 20h

Inflammation continues to shorten transplant survival. 🧠💉This freely downloadable review paper discusses whether vagus nerve stimulation, which harnesses the body’s own anti-inflammatory reflex, can help protect grafts and improve outcomes. #TXPforAll tinyurl.com/b94k3nvb

transplantation.bsky.social @transplantation.bsky.social · 21h

BK polyomavirus in kidney transplant recipients: BKPyV QNAT reliably rules out BKVAN when negative, but positive results cannot distinguish true tissue-invasive infection. #TXPforAll #OpenAccess #Kidneytransplantation tinyurl.com/32kjdyvh

transplantation.bsky.social @transplantation.bsky.social · 1d

Extracorporeal photopheresis may prevent trained immunity and promote transplant tolerance, offering a potential new prophylactic strategy. #TXPforAll #OpenAccess #immunology tinyurl.com/ytccs2dv

transplantation.bsky.social @transplantation.bsky.social · 2d

In kidney transplant recipients, sotagliflozin (SGLT1/2 inhibitor) caused an initial eGFR dip—but changes were largely reversible after withdrawal.
🔹Well tolerated overall
🔹Adherence unaffected by eGFR reporting strategy
Promising safety signal for KTRs tinyurl.com/mv9p49k3

transplantation.bsky.social @transplantation.bsky.social · 6d

#TBT to this week's featured top downloaded paper from 2022: Quality Metrics in Solid Organ Transplantation
A Systematic Review #Transplantation #Med tinyurl.com/yynbnvb8

transplantation.bsky.social @transplantation.bsky.social · 7d

Top #Transplantation articles this month!
🔹 EVs for noninvasive heart rejection monitoring
🔹 Pregnancy after organ transplant: new guidance
🔹 Kidney care in heart transplant patients
🔹 Donor cfDNA in pediatric kidney rejection

journals.lww.com/transplantjo...

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transplantation.bsky.social @transplantation.bsky.social · 7d

The bioinformatic tool HLA-EP-RESOLVER accurately predicts antibody reactivity to rare HLA alleles using eplet analysis. Validated in sensitized patients, it helps identify acceptable/unacceptable antigens in the era of high-resolution donor typing. #HLA tinyurl.com/2m9nm6ek

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transplantation.bsky.social @transplantation.bsky.social · 8d

Few upper extremity transplants are done worldwide, leaving patients with tough choices. This study shows how hopes, pressures, and quality-of-life concerns shape decision-making—and why better informed consent is key. #TXPforAll @DrMaceyLevan tinyurl.com/5b4rwj6a

transplantation.bsky.social @transplantation.bsky.social · 9d

Brain death triggers early complement activation in donor kidneys. High complement levels correlated with delayed graft function—highlighting a key target to improve outcomes. #TXPforAll #Transplantation #immunology #OpenAccess tinyurl.com/mvysuzk2

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transplantation.bsky.social @transplantation.bsky.social · 12d

This new tool makes kidney allocation policy design faster—cutting simulation time from 6 hours to just 15 seconds. Faster models mean fairer, smarter decisions for patients waiting on a transplant. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4ykbarrs

transplantation.bsky.social @transplantation.bsky.social · 13d

#TBT to this week's featured top downloaded paper from 2022: URINARY TRACT INFECTIONS IN RENAL TRANSPLANT RECIPIENTS IN THREE YEARS Recipients #Transplantation #Med tinyurl.com/4mpn66a9

transplantation.bsky.social @transplantation.bsky.social · 14d

Not all antibody tests agree: this study shows big differences between commercial assays for non-HLA antibodies in kidney transplant rejection. Standardization is urgently needed to clarify their role in AMR and graft loss. #TXPforAll #Transplantation tinyurl.com/c6s5mtk7

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transplantation.bsky.social @transplantation.bsky.social · 15d

Undetected donor infections remain a concern in transplantation. Model shows the critical care interval before screening lowers residual risk—cutting it by ~44% for HCV, 23% for HIV, and 7% for HBV—supporting testing donors. @UniMelb tinyurl.com/4v9r9her

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transplantation.bsky.social @transplantation.bsky.social · 16d

BK virus is a major cause of kidney transplant failure. This study shows that boosting virus-fighting immune cells in the lab—and adding checkpoint inhibitors—could make future treatments more effective at protecting transplanted kidneys. #TXPforAll tinyurl.com/5n76fk77

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transplantation.bsky.social @transplantation.bsky.social · 19d

Graft rejection forces lifelong immunosuppression—bringing risks of infection & cancer. Veltman et al. explores extracorporeal photopheresis as a targeted alternative, highlighting immune pathways & biomarkers guide its use in solid organ transplantation tinyurl.com/mrm2ytjm

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transplantation.bsky.social @transplantation.bsky.social · 20d

#TBT to this week's featured top downloaded paper from 2022: Immunosuppression and Reproductive Health After Kidney Transplantation #Transplantation #Med tinyurl.com/42untm8z

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transplantation.bsky.social @transplantation.bsky.social · 21d

New in Transplantation! Patient Selection for Xenotransplant Human Clinical Trials: A Data-driven Approach. #TXPforAll #Transplantation tinyurl.com/4fwsv44c

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transplantation.bsky.social @transplantation.bsky.social · 22d

Extracorporeal photopheresis = giving your immune system a light makeover 💡. This review explores how “photopheresates” could be supercharged—tweaking immune cells to either calm rejection or boost defense. #TXPforAll #Transplantation #OpenAccess tinyurl.com/2wztekfn

transplantation.bsky.social @transplantation.bsky.social · 23d

Study shows that the molecule miR-374b-5p worsens liver damage during transplantation and fuels liver cancer growth. Blocking it with a targeted gene therapy reduced tissue injury and cut tumor burden by 56%, pointing to a promising new treatment approach tinyurl.com/39c4vskz

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transplantation.bsky.social @transplantation.bsky.social · 26d

Men and women face different risks while waiting for transplants. Younger women with kidney disease are at higher risk, older women often do better, and liver transplant risks shift with time—showing why sex matters in transplant care!! #TXPforAll tinyurl.com/4mywsrxm

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transplantation.bsky.social @transplantation.bsky.social · 27d

#TBT to this week's featured top downloaded paper from 2022: Acute Kidney Injury After Liver Transplantation
#Transplantation #Med tinyurl.com/ytb6wdrp

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transplantation.bsky.social @transplantation.bsky.social · 28d

New swine study of intestinal transplantation shows that partial MHC class II matching can induce a unique “split tolerance” driven by donor regulatory T cells. @ColumbiaMed #TXPforAll #Transplantation tinyurl.com/mscuevjv

transplantation.bsky.social @transplantation.bsky.social · 29d

Extracorporeal photopheresis shows promise in reducing donor-specific antibodies and improving long-term transplant survival. #TXPforAll #OpenAccess #Transplantation tinyurl.com/md9b2h3w

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transplantation.bsky.social @transplantation.bsky.social · Sep 15

Kidney disease is common after heart transplant. A Spanish expert consensus offers guidance on its management and when to consider kidney transplantation. #TXPforAll #Transplantation tinyurl.com/28mu34tp

transplantation.bsky.social @transplantation.bsky.social · Sep 12

Extracorporeal photopheresis is emerging as a novel therapy to regulate alloimmunity and prevent transplant rejection. #TXPforAll #OpenAccess #Transplantation tinyurl.com/yfv4ywau