Tim Weber
@timweber.bsky.social
Image scientist and biomedical engineer at MIT.
Thankful for this blog piece by @ptrrupprecht.bsky.social on the Dirigo project. Glad you liked the posts!
gcamp6f.com/2025/11/14/d...
gcamp6f.com/2025/11/14/d...
Dirigo: a future Python alternative to Scanimage?
Over the last 20 years, many microscopes that are capable of resonant scanning two-photon microscopy have converged on using ScanImage, a powerful software package with many strengths but also two โฆ
gcamp6f.com
November 21, 2025 at 4:24 PM
Thankful for this blog piece by @ptrrupprecht.bsky.social on the Dirigo project. Glad you liked the posts!
gcamp6f.com/2025/11/14/d...
gcamp6f.com/2025/11/14/d...
๐ฌ New post in the "Introducing Dirigo" series: Worker Products
Products are the way information is carried from node to node along the acquisition pipeline. TBH I'm pretty proud of this system ๐
Introductory post below ๐
Products are the way information is carried from node to node along the acquisition pipeline. TBH I'm pretty proud of this system ๐
Introductory post below ๐
Introducing Dirigo #5: Worker Products
Iโm writing a series of โbite-sizedโ posts about Dirigo, my modular image-acquisition framework for laser-scanning microscopy. Previous posts: [#1 Intro], [#2 Acquisition pipeline], [#3 Hardware inte...
forum.image.sc
November 4, 2025 at 10:37 PM
๐ฌ New post in the "Introducing Dirigo" series: Worker Products
Products are the way information is carried from node to node along the acquisition pipeline. TBH I'm pretty proud of this system ๐
Introductory post below ๐
Products are the way information is carried from node to node along the acquisition pipeline. TBH I'm pretty proud of this system ๐
Introductory post below ๐
Reposted by Tim Weber
Introducing Thorlabs' New VantageProยฎ Resonant Scanner System!
Learn more at https://bit.ly/4qiTwMZ
Ideal for high-speed imaging, this resonant scanner is designed to deflect a laser beam from its original trajectory and continuously scan it over a user-controlled scan angle.
Learn more at https://bit.ly/4qiTwMZ
Ideal for high-speed imaging, this resonant scanner is designed to deflect a laser beam from its original trajectory and continuously scan it over a user-controlled scan angle.
October 24, 2025 at 8:45 PM
Introducing Thorlabs' New VantageProยฎ Resonant Scanner System!
Learn more at https://bit.ly/4qiTwMZ
Ideal for high-speed imaging, this resonant scanner is designed to deflect a laser beam from its original trajectory and continuously scan it over a user-controlled scan angle.
Learn more at https://bit.ly/4qiTwMZ
Ideal for high-speed imaging, this resonant scanner is designed to deflect a laser beam from its original trajectory and continuously scan it over a user-controlled scan angle.
Reposted by Tim Weber
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 6, 2025 at 5:52 PM
We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
๐ฌ ๐ฌ New post in the "Introducing Dirigo" series: Unit quantities
Why units matter (think 100 ยตm vs 100 mm ๐ฌ), parsing โ400 umโ/โ8 kHzโ/"125 MS/s", expressive types, and unit-checked math.
Dirigo achieves this with a light-weight Pint-inspired layer used everywhere units are relevant.
Why units matter (think 100 ยตm vs 100 mm ๐ฌ), parsing โ400 umโ/โ8 kHzโ/"125 MS/s", expressive types, and unit-checked math.
Dirigo achieves this with a light-weight Pint-inspired layer used everywhere units are relevant.
Introducing Dirigo #4: Unit quantities
Iโm writing posts to introduce Dirigo, a flexible image acquisition framework targeting laser scanning applications. Previous posts: #1: Intro, #2: Acquisition pipeline composition, #3: Hardware inter...
forum.image.sc
September 18, 2025 at 12:25 PM
๐ฌ ๐ฌ New post in the "Introducing Dirigo" series: Unit quantities
Why units matter (think 100 ยตm vs 100 mm ๐ฌ), parsing โ400 umโ/โ8 kHzโ/"125 MS/s", expressive types, and unit-checked math.
Dirigo achieves this with a light-weight Pint-inspired layer used everywhere units are relevant.
Why units matter (think 100 ยตm vs 100 mm ๐ฌ), parsing โ400 umโ/โ8 kHzโ/"125 MS/s", expressive types, and unit-checked math.
Dirigo achieves this with a light-weight Pint-inspired layer used everywhere units are relevant.
๐ฌ New post in the "Introducing Dirigo" series! (my project to build a flexible backend for sci. image acquisition)
This week: the Digitizer interfaceโhow to abstract the main data-collection device in laser-scanning microscopy to support different cards through a single, oscilloscope-inspired API.
This week: the Digitizer interfaceโhow to abstract the main data-collection device in laser-scanning microscopy to support different cards through a single, oscilloscope-inspired API.
Introducing Dirigo โ Post #3: Hardware extensibility & the Digitizer interface
Iโm writing weekly posts to introduce Dirigo, a flexible image acquisition framework for Python. In the last post, I introduced the reconfigurable acquisition pipeline. In this post, Iโll describe har...
forum.image.sc
August 25, 2025 at 2:38 PM
๐ฌ New post in the "Introducing Dirigo" series! (my project to build a flexible backend for sci. image acquisition)
This week: the Digitizer interfaceโhow to abstract the main data-collection device in laser-scanning microscopy to support different cards through a single, oscilloscope-inspired API.
This week: the Digitizer interfaceโhow to abstract the main data-collection device in laser-scanning microscopy to support different cards through a single, oscilloscope-inspired API.
New post in the "Introducing Dirigo" series!
In this one, I share a short video clip demo & walk through how Dirigo organizes image acquisition as a reconfigurable dataflow graph.
๐ forum.image.sc/t/introducin...
In this one, I share a short video clip demo & walk through how Dirigo organizes image acquisition as a reconfigurable dataflow graph.
๐ forum.image.sc/t/introducin...
August 19, 2025 at 3:46 PM
New post in the "Introducing Dirigo" series!
In this one, I share a short video clip demo & walk through how Dirigo organizes image acquisition as a reconfigurable dataflow graph.
๐ forum.image.sc/t/introducin...
In this one, I share a short video clip demo & walk through how Dirigo organizes image acquisition as a reconfigurable dataflow graph.
๐ forum.image.sc/t/introducin...
Just posted Part 1 of a new series on "Dirigo", my design for a very flexible, extensible backend for scientific image acquisition.
Iโll be posting weekly to spark feedback and find collaborators.
This first post covers the intro & high-level design. ๐
Iโll be posting weekly to spark feedback and find collaborators.
This first post covers the intro & high-level design. ๐
Designing Dirigo: a flexible, extensible backend for scientific image acquisition
Some time ago, on a certain social platform that has since been renamed, I asked for suggestions on laser scanning microscopy acquisition control software. I was looking for something in the spirit of...
forum.image.sc
August 11, 2025 at 5:23 PM
Just posted Part 1 of a new series on "Dirigo", my design for a very flexible, extensible backend for scientific image acquisition.
Iโll be posting weekly to spark feedback and find collaborators.
This first post covers the intro & high-level design. ๐
Iโll be posting weekly to spark feedback and find collaborators.
This first post covers the intro & high-level design. ๐
I see strides being made in open source electronics www.crowdsupply.com may be easier here because scalability (PCB fab, pick and place, etc). What would this look like for a microscope frame?
Where engineers launch and sell the world's best hardware
Bringing original, useful, respectful open hardware into existence.
www.crowdsupply.com
February 13, 2025 at 4:20 PM
I see strides being made in open source electronics www.crowdsupply.com may be easier here because scalability (PCB fab, pick and place, etc). What would this look like for a microscope frame?
'Open source' is a great concept--but I think the bottleneck is fabrication. We need a low-cost partner building open designs at reasonable scale. Open source works so well for software because the 'fabrication' is simply computer execution (+/-compiling and distribution).
February 13, 2025 at 4:19 PM
'Open source' is a great concept--but I think the bottleneck is fabrication. We need a low-cost partner building open designs at reasonable scale. Open source works so well for software because the 'fabrication' is simply computer execution (+/-compiling and distribution).
So much fun writing a K99 through this..
January 28, 2025 at 1:31 PM
So much fun writing a K99 through this..
Do you think it's trolling you (which would be kinda brilliant) or is this really its best shot?
January 28, 2025 at 1:29 PM
Do you think it's trolling you (which would be kinda brilliant) or is this really its best shot?
Don't sleep on Strava
December 2, 2024 at 2:27 PM
Don't sleep on Strava
I just made my Alazar digitizer Python bindings public. Provides API binding, a ton of enumerations with helper methods, and data parsing.
github.com/tweber225/at...
github.com/tweber225/at...
GitHub - tweber225/atsbindings: Python bindings for AlazarTech API.
Python bindings for AlazarTech API. Contribute to tweber225/atsbindings development by creating an account on GitHub.
github.com
November 26, 2024 at 11:20 PM
I just made my Alazar digitizer Python bindings public. Provides API binding, a ton of enumerations with helper methods, and data parsing.
github.com/tweber225/at...
github.com/tweber225/at...