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Amir, PharmD @theamirimani.bsky.social · 12m

Those kids are probably too autistic to be allergic to peanuts smdh

Reposted by Amir, PharmD

MedPage Today @medpagetoday.com · 4h

Fewer toddlers developed peanut allergies after guidelines recommended introducing peanut products in infancy, a large primary care registry study showed. 🥜⬇️

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Amir, PharmD @theamirimani.bsky.social · 29m

2030: "A pair of thieves made off with a Rembrandt after successfully distracting Louvre Security by yelling 'Hey! What's that?!'"

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Amir, PharmD @theamirimani.bsky.social · 33m

Happy to see the tradition of "robbing the Louvre in the most basic way possible" return.

Article on 2025 Louvre robbery stating thieves just drove a truck with a ladder up to the museum on a Sunday morning.

Wikipedia article on the 1911 theft of the Mona Lisa stating the thief walked in one morning when the museum was closed the visitors, grabbed the painting when the room was empty, wrapped it in a shirt and left.

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Amir, PharmD @theamirimani.bsky.social · 3d

*Looking over at the US*
"Damn that's fucked up"

*Get email from Ontario grad student union*
"Hey wait a minute"

Except from email regarding Ontario Bill 33:

WHAT IS BILL 33

Bill 33 is an omnibus bill currently at Second Reading that bundles unrelated reforms affecting child welfare, K-12 education, and post-secondary institutions. Schedule 3 of the bill targets colleges and universities through three dangerous provisions:

Fee Regulations (Section 21.1): Gives Cabinet authority over student union fees, threatening health/dental plans, food programs, legal support, and advocacy services

Merit-Based Admissions (Section 16.0.2): Allows Cabinet to control university admissions criteria, risking equity programs and comprehensive assessment

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Amir, PharmD @theamirimani.bsky.social · 7d

I agree. I think the destructiveness of gambling addiction/problem gambling never really reached the public eye?

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Amir, PharmD @theamirimani.bsky.social · 21d

I spent so much talking to people about ivermectin or HCQ or Azithro. So much time on vaccines making you magnetic or infertile or autistic.

There are valuable discussions to be had and questions to ask in healthcare. Those weren't it.

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Amir, PharmD @theamirimani.bsky.social · 21d

One of the insidious problems with medical disinformation is that it "hogs the air".

We spend time debunking BS and assuaging fears that we could have spent having actually valuable discussions.

#MedSky #RxSky

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Amir, PharmD @theamirimani.bsky.social · 27d

Giving real life Quietus vibes

Qiuetus suicide kit from the movie Children of Men.

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Amir, PharmD @theamirimani.bsky.social · Sep 7

A 0.5% risk of a severe outcome led to a generational change.

Something to keep in mind

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Amir, PharmD @theamirimani.bsky.social · Sep 7

There's another lesson in polio too. Humor me a bit:

❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis?

A) 5%

B) 12%

C) 0.5%

D) 3%

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Amir, PharmD @theamirimani.bsky.social · Aug 21

"Canadian values" probably meaning something different to pretty much every single person polled.

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Amir, PharmD @theamirimani.bsky.social · Jul 24

Fun fact: This year is the *1000 year anniversary* of The Canon of Medicine. An encyclopedia that was used in European universities until the 17th century.

One that was influenced by and organized Persian, Greek, Chinese, and Indian medical knowledge of the time.

en.wikipedia.org/wiki/The_Can...

The Canon of Medicine - Wikipedia

en.wikipedia.org

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Amir, PharmD @theamirimani.bsky.social · Jul 24

I grew up learning about Persian scientists during the Islamic Golden Age like Avicenna or Al-Razi. Their work was foundational for later advances in the renaissance and modern medicine as we know it.

They considered their work universal. Never described it as practicing “Western Medicine”.

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Amir, PharmD @theamirimani.bsky.social · Jul 24

*Tiny soapbox*

Calling it "Western Medicine" whitewashes historical and ongoing contributions made to modern medicine by the global community. It's meaningless and unnecessarily divisive.

#RxSky #MedSky

The book spines for the Canon of Medicine.

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Amir, PharmD @theamirimani.bsky.social · Jul 16

Also turmeric in food is fine folks. Very hard to overdo it there.

I'd be very sad if this post led people to under-seasoning their food 😭

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Amir, PharmD @theamirimani.bsky.social · Jul 16

Honestly maybe they'll find something. But data so far is lacking.

Plus one of the reasons turmeric "worked" in some in vitro studies is because it messes with some lab tests.

I wrote a few lines about efficacy in 1 study here

bsky.app/profile/thea...

Amir, PharmD @theamirimani.bsky.social · Jul 16

In case there's interest: Here's a study on turmeric for OA that's got ok methodology (small though).

I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper.

#Medsky
www.acpjournals.org/doi/10.7326/...

Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee Osteoarthritis: A Randomized Trial: Annals of Internal Medicine: Vol 173, No 11

Background: Current pharmacologic therapies for patients with osteoarthritis are suboptimal. Objective: To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion–...

www.acpjournals.org

Amir, PharmD @theamirimani.bsky.social · Jul 16

If you still want more to read: Liver Tox is king 👑 when it comes to this info

www.ncbi.nlm.nih.gov/books/NBK548...

Turmeric

Turmeric is a spice and popular botanical product derived from the roots of the plant Curcuma longa found mostly in India and Southern Asia. Turmeric has an intense yellow color and distinct taste and...

www.ncbi.nlm.nih.gov

Amir, PharmD @theamirimani.bsky.social · Jul 16

And unfortunately, if you care about significant safety outcomes like liver injury, a sample size of 70 is just not gonna cut it 🤷

That's not the authors' fault. That's just how more rare side effects work.

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Amir, PharmD @theamirimani.bsky.social · Jul 16

⏩ The pain score they use (VAS) is out of 100mm.

⏩ 9.1 points doesn't meet the authors' own definition of a "Minimum Clinically Important Difference/MCID" (i.e. the bare minimum improvement that folks would actually care about).

⏩ There were no changes in synovitis or quality of life.

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Amir, PharmD @theamirimani.bsky.social · Jul 16

Look at the company's material or the study results and it looks pretty good!

Statistically significant reduction in pain scores!

9.1mm! That's a number!

But folks who know the literature or who have the University affiliation/money to look at the full study would point out...

Highlighted: "CL improved VAS pain compared with placebo by 9.1mm"

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Amir, PharmD @theamirimani.bsky.social · Jul 16

In case there's interest: Here's a study on turmeric for OA that's got ok methodology (small though).

I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper.

#Medsky
www.acpjournals.org/doi/10.7326/...

Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee Osteoarthritis: A Randomized Trial: Annals of Internal Medicine: Vol 173, No 11

Background: Current pharmacologic therapies for patients with osteoarthritis are suboptimal. Objective: To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion–...

www.acpjournals.org

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Amir, PharmD @theamirimani.bsky.social · Jul 15

It's niche knowledge even among HCWs

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Amir, PharmD @theamirimani.bsky.social · Jul 15

If this was a prescription medicine, regulators would demand new safety data if you wanted to alter your formulation this way.

But it's a supplement so people are left to fend for themselves. Wild West stuff 🤠

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Amir, PharmD @theamirimani.bsky.social · Jul 15

The problem is that most safety data is based on regular turmeric supplements that don't use black pepper extract to boost absorption.

Turmeric's systemic absorption sucks, which makes it safe.

You start boosting that absorption with an additive and the math changes.

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