Estudios recientes revelan nuevos hallazgos sobre los daños que provoca el COVID-19 en la actividad cerebral.

ABSTRACT Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted to 33° to 37°C. In this work, we show that a...

New calculation of viral spread suggests that rapid elimination of SARS-CoV-2-like viruses is scientifically feasible, though social challenges remain

ABSTRACT The SARS-Cov-2 pandemic demonstrated the challenge of controlling a zoonotic disease with high infection fatality rates, including the evolution of more transmissible variants. In dealing with future similar pandemics, the question of eliminat...

The Thursday Edition of the virus update with the latest news and data of the day. My Website: www.datareport.info My Twitter username: @CovidDataReport My Bluesky account: https://bsky.app/profile/datareport.bsky.social My new Facebook page: https://w...

A litter of kittens in the Netherlands died after likely contracting H5N1 bird flu, according to Dutch Agriculture Minister Femke Wiersma. At least one of the kittens was confirmed to have carried the virus. The letter sent to the Dutch parliament by Minister Wiersma, dated Monday, outlines findings from Wageningen Bioveterinary Research, which reported that […]

The Thursdsy Edition of the virus update with the latest news and data of the day. My Website: www.datareport.info My Twitter username: @CovidDataReport My Bluesky account: https://bsky.app/profile/datareport.bsky.social My new Facebook page: https://w...

At the WHYY (150 North 6th Street, Philadelphia), on December 14, 2025, 1pm to 3pm EST: Joshua Roman presents Immunity, a one-hour multimedia concert featuring cello performances of Bach, Caroline Shaw, and his original compositions, combined with stor...

At the ABV Gallery (1206 Metropolitan Avenue Southeast, Atlanta), on December 13, 2025, 1pm to 3pm EST: Joshua Roman presents Immunity, a one-hour multimedia concert featuring cello performances of Bach, Caroline Shaw, and his original compositions, co...

At the Lina Cerrone Fine Art Gallery (2239 Northwest 2nd Avenue, Miami), on December 11, 2025, 12pm to 2pm EST: Joshua Roman presents Immunity, a one-hour multimedia concert featuring cello performances of Bach, Caroline Shaw, and his original composit...

At The Arbory (2219 West Grand Avenue, Chicago) on December 8, 2025, Joshua Roman presents Immunity, a one-hour multimedia concert featuring cello performances of Bach, Caroline Shaw, and his original compositions, combined with storytelling on themes o...

The Wednesday Edition of the virus update with the latest news and data of the day. My Website: www.datareport.info My Twitter username: @CovidDataReport My Bluesky account: https://bsky.app/profile/datareport.bsky.social My new Facebook page: https://...

The concert is free to all with an RSVP, but it’s intended first and foremost for audience members living with long COVID and other chronic illnesses.

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ABSTRACT Evidence is emerging that long COVID is at least as prevalent in the Global South as the Global North, but literature on long COVID healthcare in the Global South is in its infancy. Brazil is seeing significant levels of debility due to long C...

Bird flu viruses are a particular threat to humans because they can replicate at temperatures higher than a typical fever, one of the body's ways of stopping viruses in their tracks, according to new research led by the universities of Cambridge and Glasgow.

Researchers found persistent microclot and NET structures in Long COVID blood that may explain long-lasting symptoms. Researchers examining Long COVID have identified a structural connection between circulating microclots and neutrophil extracellular traps (NETs). The discovery indicates that the two may interact in the body in ways that could lead to harmful effects when these processes become unregulated. Understanding Microclots Microclots are abnormal clusters of blood clotting proteins that move through the bloodstream. The term entered scientific use in 2021, when Prof Resia Pretorius from Stellenbosch University’s Department of Physiological Sciences reported finding these unusual microclots in blood samples from people with COVID-19. The observation received widespread attention because of its potential relevance to clotting complications seen during the pandemic. What NETs Do in the Immune System Dr. Alain Thierry and his team at the Montpellier Cancer Institute (IRCM) at INSERM in Montpellier were among the first to show that NETs play a major role in COVID-19. NETs form during a process called NETosis, in which neutrophils release their DNA to create thin strands coated with enzymes that quickly trap and neutralize harmful microbes. Although NETs are part of the body’s defenses, producing them in excessive amounts can contribute to inflammatory and clotting disorders. Such overproduction has been associated with severe infections, autoimmune diseases, cancer, diabetes, and arthritis. Dr. Thierry notes that ongoing and repeated NET formation, driven by inflammatory and clotting cycles, may worsen disease outcomes. Investigating Microclot NETs Interactions in Long COVID To explore whether microclots and NETs interact in Long COVID, the research teams led by Prof Pretorius and Dr Thierry joined forces. Their goal was to determine whether these two features of the blood might be linked in ways that help explain persistent symptoms. Key Findings From the Analysis Using imaging flow cytometry and fluorescence microscopy, the researchers conducted detailed measurements of microclots and NETs in the plasma of Long COVID patients and compared them to samples from healthy volunteers. They also evaluated NETs by examining proteic markers and circulating DNA. Their study revealed several notable results: Biomarkers related to both microclots and NETs were significantly higher in Long COVID patients. Patients showed not only more microclots but also larger ones. The researchers identified a structural association between microclots and NETs in all subjects, which appeared far stronger in Long COVID patients. “This finding suggests the existence of underlying physiological interactions between microclots and NETs that, when dysregulated, may become pathogenic,” explains Dr. Thierry. AI Tools Improve Diagnostic Accuracy Artificial Intelligence methods, including machine learning, were added to the biomarker analysis. These tools allowed the researchers to clearly differentiate between Long COVID patients and healthy individuals. The algorithms also highlighted the most informative biomarker combinations, offering potential pathways for personalized care. According to Prof Pretorius, the findings point to a significant buildup of microclots in Long COVID patients, likely supported by an overproduction of NETs: “This interaction could render microclots more resistant to fibrinolysis, promoting their persistence in circulation and contributing to chronic microvascular complications,” she explains. Implications for Treatment and Future Biomarkers By identifying how NETs may help stabilize microclots, the study adds important insight into the biological processes underlying Long COVID. The results support the development of therapies aimed at reducing harmful clotting and inflammation. The work also advances efforts to identify new biomarkers for diagnosing and monitoring post-viral conditions. As the researchers conclude, “The combination of advanced imaging techniques and machine learning confers methodological robustness and contributes significantly to the ongoing scientific discourse on post-viral syndromes,” they conclude. Reference: “Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients” by Alain R. Thierry, Tom Usher, Cynthia Sanchez, Simone Turner, Chantelle Venter, Brice Pastor, Maxine Waters, Anel Thompson, Alexia Mirandola, Ekaterina Pisareva, Corinne Prevostel, Gert J. Laubscher, Douglas B. Kell and Etheresia Pretorius, 2 October 2025, Journal of Medical Virology. DOI: 10.1002/jmv.70613 Never miss a breakthrough: Join the SciTechDaily newsletter. Follow us on Google and Google News.

ABSTRACT In the early phase of the pandemic, we were among the first to postulate that neutrophil extracellular traps (NETs) play a key role in COVID-19 pathogenesis. This exploratory prospective study based on 279 individuals showed that plasma levels...

ABSTRACT Background Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute clinical pathologies, including various coagulopathies that may be accompan...

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ABSTRACT The persistence of vasculo-thrombotic complications has been put forward as a possible contributing factor in the Long COVID (LC) syndrome. Given the recently reported separate demonstration of the association of LC with elevated levels of het...

ABSTRACT Long-term consequences of SARS-CoV-2 infection are unknown since recovered individuals can experience symptoms and latent viral reactivation for months. Indeed, acute post-infection sequelae have also been observed in other respiratory viral i...

The Tuesday Edition of the virus update with the latest news and data of the day. My Website: www.datareport.info My Twitter username: @CovidDataReport My Bluesky account: https://bsky.app/profile/datareport.bsky.social My new Facebook page: https://ww...

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