tasalk.bsky.social
tasalk.bsky.social
@tasalk.bsky.social
Reposted by tasalk.bsky.social
We have now moved onto the next phase of using som real-world data to test the model.

Watch this space!
September 25, 2025 at 9:51 AM
Reposted by tasalk.bsky.social
This fall, I'll probably take a "harm-reduction" approach to LLMs in the big 1st-year lecture course I'm co-teaching. The course requires us to teach writing, and I don't think it's possible to eliminate AI use, so I'll combine measures to discourage or mitigate it. docs.google.com/document/d/1...
ChatGPT Harm Reduction for Writing Assignments
ChatGPT Harm Reduction for Writing Assignments Assumptions: It is worthwhile to teach students to research and write essays. AI detectors are unreliable. Few, if any, (non-carceral) measures guarante...
docs.google.com
June 2, 2025 at 8:52 PM
Reposted by tasalk.bsky.social
New #BulletinMathBio paper by Sara Amato and Andrea Arnold on A Data-Informed Mathematical Model of Microglial Cell Dynamics During Ischemic Stroke in the Middle Cerebral Artery.

link.springer.com/article/10.1...
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A Data-Informed Mathematical Model of Microglial Cell Dynamics During Ischemic Stroke in the Middle Cerebral Artery - Bulletin of Mathematical Biology
Neuroinflammation immediately follows the onset of ischemic stroke in the middle cerebral artery. During this process, microglial cells are activated in and recruited to the penumbra. Microglial cells...
link.springer.com
January 25, 2025 at 6:02 PM
Reposted by tasalk.bsky.social
New #BulletinMathBio paper by Matthew J. Penn, Neil Scheidwasser, Christl A. Donnelly, David A. Duchêne, and Samir Bhatt on Bayesian Inference of Phylogenetic Distances: Revisiting the Eigenvalue Approach.

link.springer.com/article/10.1...
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Bayesian Inference of Phylogenetic Distances: Revisiting the Eigenvalue Approach - Bulletin of Mathematical Biology
Using genetic data to infer evolutionary distances between molecular sequence pairs based on a Markov substitution model is a common procedure in phylogenetics, in particular for selecting a good star...
link.springer.com
January 27, 2025 at 4:39 AM
Reposted by tasalk.bsky.social
We co-wrote this paper and would love some feedback from NHS staff involved in bed management for others' thoughts on its potential practical utility in practice (no knowledge of maths necessary!)

DM Tahani to let her know that you're interested!
January 29, 2025 at 2:01 PM
Reposted by tasalk.bsky.social
Here's the final published paper, co-authored with @tasalk.bsky.social

Next step is to validate it with empirical data!

(thanks to @universityofessex.bsky.social for support in producing this paper, and allowing it to be open access)
A compartmental model to describe acute medical in-patient flow through a hospital
Managing patient flow in hospitals is a critical part of effective secondary care. Considering a hospital as a multi-compartment system through which patients pass, we will derive relevant equations t...
www.cell.com
February 3, 2025 at 12:43 PM

I've devised a model for analysis of unplanned hospital bed use.

I am looking for some NHS clinical/managerial decision-makers to interview about your thoughts on this.

Get in touch!

papers.ssrn.com/sol3/papers....
A Compartmental Model to Describe Acute Medical In-Patient Flow Through a Hospital
Health care is becoming increasingly complex, especially in secondary care. Hospital bed numbers per capita in the United Kingdom (UK) are lower than many Europ
papers.ssrn.com
January 28, 2025 at 6:49 AM
Thank you Kit, still lots to learn from you and hospital work. Very honoured to be your co- author in this project.
Delighted to report that a paper I co-authored with @tasalk.bsky.social has been accepted for publication.

It will be open access, thanks to the support of @essexuni.bsky.social.

Preprint available (minor revisions since then).

Excited now to move on to phase 2, validating the model!
A Compartmental Model to Describe Acute Medical In-Patient Flow Through a Hospital
Health care is becoming increasingly complex, especially in secondary care. Hospital bed numbers per capita in the United Kingdom (UK) are lower than many Europ
ssrn.com
January 24, 2025 at 6:04 PM
Reposted by tasalk.bsky.social
Welcome to Bluesky, @mbs-journal.bsky.social! It's great to have other mathematical biology journals and societies on here!

@nitmb.bsky.social @smtpb.bsky.social
December 17, 2024 at 4:05 PM
Reposted by tasalk.bsky.social
New #BulletinMathBio paper by Tyler Simmons and Doron Levy on Targeting CD4+ T cell Exhaustion to Improve Future Immunotherapy Strategies.

link.springer.com/article/10.1...
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Targeting CD4+ T cell Exhaustion to Improve Future Immunotherapy Strategies - Bulletin of Mathematical Biology
As of late, reinvigoration of exhausted T cells as a form of immunotherapy against cancer has been a promising strategy. However, inconsistent results highlight the uncertainties in the current unders...
link.springer.com
December 3, 2024 at 1:31 PM
Reposted by tasalk.bsky.social
Reposted by tasalk.bsky.social
So cool to see this go to an amazing mathematical biologist, congrats!!

And I’m honored to win the Leah Edelstein-Keshet prize this year from SMB @smbmathbiology.bsky.social can’t wait for Edmonton, Canada next year 🌲🏔️
#mathonco
Congratulations to Dr. Leah Edelstein-Keshet, Professor Emerita at the University of British Columbia, for winning the 2025 CRM-Fields-PIMS prize! Dr. Edelstein-Keshet is a trailblazer in mathematical biology.

Read more about her work at tinyurl.com/pb9f8w6w
December 6, 2024 at 2:27 AM
Reposted by tasalk.bsky.social
New #BulletinMathBio paper by Jordan Collignon, Wesley Naeimi, Tricia R. Serio, and @suzannesindi.bsky.social titled "[PSI]-CIC: A Deep-Learning Pipeline for the Annotation of Sectored Saccharomyces cerevisiae Colonies".

link.springer.com/article/10.1...
[PSI]-CIC: A Deep-Learning Pipeline for the Annotation of Sectored Saccharomyces cerevisiae Colonies - Bulletin of Mathematical Biology
The $$[PSI^+]$$ [ P S I + ] prion phenotype in yeast manifests as a white, pink, or red color pigment. Experimental manipulations destabilize prion phenotypes, and allow colonies to exhibit $$[psi^-]$...
link.springer.com
December 6, 2024 at 5:51 PM
Reposted by tasalk.bsky.social
We used DL characterize sectored colonies in yeast.
They sometimes get ignored but have SUCH RICH information we worked to make it easier to study them.

This work was funded by the Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences. :D
December 6, 2024 at 10:03 PM
Reposted by tasalk.bsky.social
Our new paper in #PLOSBiology is out! With Román Zapién-Campos and Arne Traulsen we worked on extracting maximum statistical information from microbiome time series data for parameter inference. Check it out!
How can we infer #microbiome dynamics parameters more accurately from time series data? This #PLOSBiology study uses stochastic models to improve parameter inference and so modeling/prediction... @florencebansept.bsky.social plos.io/3CU1RT1
November 25, 2024 at 12:34 PM
Reposted by tasalk.bsky.social
The 2025 SMB Annual Meeting is now accepting proposals for minisymposia, which are due January 16, 2025.

Minisymposia can have up to three co-organizers and up to eight speakers.

2025.smb.org/submit
#SMB2025
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December 9, 2024 at 1:17 PM
Reposted by tasalk.bsky.social
Glorious autumn day! 🌞
October 27, 2024 at 1:12 PM
Reposted by tasalk.bsky.social
beautiful morning on the Thames, just a hint of autumnal mist
October 4, 2024 at 7:00 AM
Reposted by tasalk.bsky.social
Vincent's Bedroom in Arles, 1889
October 3, 2024 at 11:27 PM