Taghon Lab
@taghonlab.bsky.social
250 followers 85 following 9 posts
The Taghon Lab - Unraveling human T cell development - Ghent University (Belgium) http://www.taghonlab.ugent.be
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Our research on human γδ T cells is in collaboration with the lab of David Vermijlen @ulbruxelles.bsky.social
u-cri.ulb.be/index.php?ac...
In this context, he is looking for a postdoc with experience in molecular biology. Apply now to become part of the team! 👇
euraxess.ec.europa.eu/jobs/306959
📣 We're hiring!
Are you:
- Looking for a PhD or postdoc position?
- Interested in human γδ T cells?
- Curious about employing single cell and spatial technologies to study their development?
Then apply now to join our lab!
ugent.be/en/work/scie...
ugent.be/en/work/scie...
To make our fantastic CITE-seq data set of postnatal thymocytes accessible to the community, we have launched a shiny app for interactive exploration. Check it out! 👇
ccgg.ugent.be/shiny/htsa_t...
Moreover, scRNA-seq and Visium spatial data can be found at cellxgene.cziscience.com/collections/...
Thanks to everyone involved in this fantastic collaboration, including our very own @lenamboehme.bsky.social and co-authors Nadav Yayon, Veronika Kedlian & Andrea Radtke!
Also grateful for funding from @chanzuckerberg.bsky.social, the Research Foundation Flanders (FWO) and Ghent University.
We also pinpointed the age-dependent tissue niches of TEC progenitors and explored the relationship of specialised TECs with Hassall’s Corpuscles.
All in all, an incredibly useful collection of data and tools with the potential to take #thymus research a step further. 👏
Using spatial transcriptomics, high-plex protein imaging and multimodal single cell data we studied the spatial trajectories of maturing thymocytes. These turned out to be remarkably stable from early gestation onwards but showed interesting differences for the CD4/CD8 lineages.
🚨Out now in Nature: Our spatial atlas of the developing thymus nature.com/articles/s41...
Together with the labs of Sarah Teichmann, Ron Germain & John Marioni we present insights into the establishment of the thymic organ structure in pre- and postnatal life through a new spatial mapping approach.
A spatial human thymus cell atlas mapped to a continuous tissue axis - Nature
A quantitative morphological framework for the human thymus reveals the establishment of the lobular cytokine network, canonical thymocyte trajectories and thymic epithelial cell distributions in...
nature.com