SYNTHEMA
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synthemaeu.bsky.social
SYNTHEMA
@synthemaeu.bsky.social
140 followers 210 following 83 posts
A cross-border hub to develop & validate #AI techniques for anonymization & synthetic data generation in rare hematological diseases 🔬🩸🇪🇺 #HorizonEU project 👉 https://synthema.eu/
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What can generative models reveal about the real data they learn from? This study by @upm.es researchers explores membership inference attacks in generative models, introducing new theory and showing how differential privacy fits in. A critical read for privacy-aware AI: synthema.eu/publications/
By generating secure, high-quality synthetic data, #SYNTHEMA empowers researchers to push the frontiers of rare-disease research — safely, ethically, and collaboratively.

Learn more: synthema.eu

#AIinHealthcare #RareDiseases #SyntheticData #HorizonEurope
SYNTHEMA builds on strong ethical and collaborative foundations:

🩺 @erneurobloodnet.bsky.social – Europe’s rare haematology network

📊Contributions to ENROL, EU RD Platform, and
@radeep.bsky.social

🤝Partnership with Flower - open-source federated learning for privacy-preserving AI
We’re validating our methods through two real-world cases:

🩸 Sickle Cell Disease
🧫 Acute Myeloid Leukaemia
AI helping clinicians improve diagnosis, prediction, and personalised care.

#RareDiseases #AIinHealthcare #SCD #AML #SickleCell #Leukaemia
Our platform brings together:
🧠 Federated Learning
🔒 Secure Multi-Party Computation
⚖️ Differential Privacy

The result: synthetic data that mimics real patterns without exposing personal information.

#FederatedLearning #SyntheticData
SYNTHEMA unites 16 partners from 10 countries to create a cross-border health-data hub for rare haematological diseases.

Together, we’re making data collaboration secure, ethical, and scalable.

#HorizonEurope #ResearchInnovation
When data is rare, progress slows. Over 450 blood-related disorders are classified as rare, yet data remains fragmented and inaccessible — limiting progress for 30M+ patients across Europe.

#HealthData #RareDiseases
Pushing the boundaries of AI-based research in rare haematological diseases.

#SYNTHEMA develops privacy-preserving AI and synthetic data to create virtual patients that improve diagnosis and treatment in rare diseases.

👉 synthema.eu

#AIinHealthcare #HorizonEurope
We’re validating our methods through two real-world cases:

🩸 Sickle Cell Disease
🧫 Acute Myeloid Leukaemia
AI helping clinicians improve diagnosis, prediction, and personalised care.

#RareDiseases #AIinHealthcare #SCD #AML #SickleCell #Leukaemia
Our platform brings together:
🧠 Federated Learning
🔒 Secure Multi-Party Computation
⚖️ Differential Privacy

The result: synthetic data that mimics real patterns without exposing personal information.

#FederatedLearning #SyntheticData
SYNTHEMA unites 16 partners from 10 countries to create a cross-border health-data hub for rare haematological diseases. 🌍

Together, we’re making data collaboration secure, ethical, and scalable.

#HorizonEurope #ResearchInnovation
When data is rare, progress slows. Over 450 blood-related disorders are classified as rare, yet data remains fragmented and inaccessible — limiting progress for 30M+ patients across Europe.

#HealthData #RareDiseases
The #HealthData4EU Cluster, which SYNTHEMA forms part of, will host the session “Ecosystems of Innovation in Healthcare: Ensuring Trust, Quality & Ethics in Data Use” at #EBDVF2025 in Copenhagen on 12–14 Nov

Event: european-big-data-value-forum.eu/2025-edition...
Cluster: synthema.eu/healthdata4eu/
Most synthetic data models assume data abundance. This study shows how transfer learning and meta-learning improve synthetic data generation for cancer research in low-data scenarios, where real clinical constraints apply.

👉 synthema.eu/publications/

#SYNTHEMA #SyntheticData #AI
Our partner i~HD is hosting a special 10th anniversary edition of its Annual Conference: “A Decade of Joining the Dots – Towards Bridging Data Spaces”

📍 3–4 Dec 2025 | Ghent, Belgium

Topics: EHDS, AI in healthcare, data quality, privacy & governance.

👉 www.i-hd.eu/ac2025
Most synthetic data models assume data abundance. This study shows how transfer learning and meta-learning improve synthetic data generation for cancer research in low-data scenarios, where real clinical constraints apply.

👉 synthema.eu/publications/

#SYNTHEMA #CancerResearch
Through collaborations with @radeep.bsky.social and ENROL, SYNTHEMA aligns rare disease datasets with European standards. This ensures interoperability across registries and hospitals, strengthening the foundation for synthetic data and AI solutions in real-world healthcare.
In #SYNTHEMA, data collection is central to building GDPR-compliant, AI-ready datasets for Sickle Cell Disease and Acute Myeloid Leukaemia. Harmonised across countries, the data supports synthetic generation, federated learning, and future rare disease research.

👉 synthema.eu/2025/09/23/d...
Data scarcity and fragmentation limit synthetic data in healthcare. This study introduces Synthetic Data Sharing, a federated learning method that improves representativeness and reduces disparities between data-rich and data-poor institutions.

👉 synthema.eu/publications/

#SYNTHEMA
Good data is not just collected, it is built with care. In #SYNTHEMA, clinical teams across Europe are creating high-quality, privacy-compliant datasets to power synthetic data and AI research in rare blood disorders.

👉Read more: synthema.eu/2025/09/23/d...
Cyber-physical systems need smarter tools for risk assessment. This study introduces an automated, simulation-based method aligned with ISO 27005. Validated through a real attack case and implemented in Spyderisk.

Read more 👉 synthema.eu/publications/
📰 The #BDVA Healthcare Task Force has published its white paper on Synthetic Data in Healthcare.

Proud to contribute alongside AISym4Med & SECURED, our sister projects in the #HEALTHDATA4EU cluster.

Read more 👉 bdva.eu/news/synthet...

#SyntheticData #SYNTHEMA
#SYNTHEMA is featured in The Innovation Platform (Issue 23), with an article on how synthetic data and federated AI are transforming research in rare blood disorders while keeping patient privacy at the core: www.innovationnewsnetwork.com/publication/...

#SyntheticData #RareDiseases
The #SYNTHEMA platform enables synthetic health data without moving sensitive patient info.
✔️ Data stays local
✔️ Federated learning across centres
✔️ FAIR-based quality & compliance

Tested in #SCD & #AML use cases. More info: synthema.eu
#SYNTHEMA is building the foundations for a future where synthetic, privacy-preserving data supports progress in rare diseases.

Beyond its two use cases, its flexible design can benefit other rare and underrepresented conditions.

More 👉 synthema.eu